Linda M Mcmanus

  • 5376 Citations
  • 41 h-Index
1973 …2020
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1973 2016

  • 5376 Citations
  • 41 h-Index
  • 102 Article
  • 1 Book
  • 1 Conference contribution
  • 1 Foreword/postscript
Filter
Article
2016
5 Citations (Scopus)

Absence of CCR2 results in an inflammaging environment in young mice with age-independent impairments in muscle regeneration

Melton, D. W., Roberts, A. C., Wang, H., Sarwar, Z., Wetzel, M. D., Wells, J. T., Porter, L., Berton, M. T., Mcmanus, L. M. & Shireman, P. K., Nov 1 2016, In : Journal of Leukocyte Biology. 100, 5, p. 1011-1025 15 p.

Research output: Contribution to journalArticle

Regeneration
Macrophages
Muscles
Sarcopenia
Monocytes
3 Citations (Scopus)

Increased Adipocyte Area in Injured Muscle With Aging and Impaired Remodeling in Female Mice

Fearing, C. M., Melton, D. W., Lei, X., Hancock, H., Wang, H., Sarwar, Z. U., Porter, L., McHale, M., Mcmanus, L. M. & Shireman, P. K., Aug 1 2016, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 71, 8, p. 992-1004 13 p.

Research output: Contribution to journalArticle

Adipocytes
Muscles
Regeneration
Skeletal Muscle
Cardiotoxins
2015
29 Citations (Scopus)

Temporal phenotypic features distinguish polarized macrophages in vitro

Melton, D. W., Mcmanus, L. M., Gelfond, J. A. & Shireman, P. K., May 1 2015, In : Autoimmunity. 48, 3, p. 161-176 16 p.

Research output: Contribution to journalArticle

Macrophages
Cytokines
Culture Media
Vascular Endothelial Growth Factor A
Blood Vessels
2014
75 Citations (Scopus)

Altered macrophage phenotype transition impairs skeletal muscle regeneration

Wang, H., Melton, D. W., Porter, L., Sarwar, Z. U., Mcmanus, L. M. & Shireman, P. K., 2014, In : American Journal of Pathology. 184, 4, p. 1167-1184 18 p.

Research output: Contribution to journalArticle

Regeneration
Monocytes
Skeletal Muscle
Macrophages
Phenotype
2012
6 Citations (Scopus)

3T magnetic resonance imaging accurately depicts radiofrequency ablation zones in a blood-perfused bovine liver model

Burns, S. K., Dodd, G. D., Mcmanus, L. M., Cardan, R. A., Peng, Q., Orsi, M. D., Head, H. W., Blakemore, D. L., Blume, J. D., Fullerton, G. D. & Green, T. J., Jun 2012, In : Journal of Vascular and Interventional Radiology. 23, 6, p. 801-808 8 p.

Research output: Contribution to journalArticle

Magnetic Resonance Imaging
Liver
NADP
Confidence Intervals
27 Citations (Scopus)

Clinical and Translational Scientist Career Success: Metrics for Evaluation

Lee, L. S., Pusek, S. N., Mccormack, W. T., Helitzer, D. L., Martina, C. A., Dozier, A. M., Ahluwalia, J. S., Schwartz, L. S., Mcmanus, L. M., Reynolds, B. D., Haynes, E. N. & Rubio, D. M., Oct 2012, In : Clinical and Translational Science. 5, 5, p. 400-407 8 p.

Research output: Contribution to journalArticle

Education
Translational Medical Research
Program Evaluation
Research
Growth
10 Citations (Scopus)

Increased fat deposition in injured skeletal muscle is regulated by sex-specific hormones

McHale, M. J., Sarwar, Z. U., Cardenas, D. P., Porter, L., Salinas, A. S., Michalek, J. E., Mcmanus, L. M. & Shireman, P. K., Feb 2012, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 302, 3

Research output: Contribution to journalArticle

Gonadal Steroid Hormones
Skeletal Muscle
Fats
Regeneration
Adipocytes
32 Citations (Scopus)
MicroRNAs
Regeneration
Cell Survival
Stem Cells
Cell Proliferation
2011
11 Citations (Scopus)

Chemoradionuclide therapy with 186Re-labeled liposomal doxorubicin: Toxicity, dosimetry, and therapeutic response

Soundararajan, A., Bao, A., Phillips, W. T., Mcmanus, L. M. & Goins, B. A., Oct 1 2011, In : Cancer Biotherapy and Radiopharmaceuticals. 26, 5, p. 603-614 12 p.

Research output: Contribution to journalArticle

Liposomes
Body Weight
Radioactivity
Therapeutics
Maximum Tolerated Dose
27 Citations (Scopus)

Chemoradionuclide therapy with186re-labeled liposomal doxorubicin in combination with radiofrequency ablation for effective treatment of head and neck cancer in a nude rat tumor xenograft model

Soundararajan, A., Dodd, G. D., Bao, A., Phillips, W. T., Mcmanus, L. M., Prihoda, T. J. & Goins, B. A., Dec 2011, In : Radiology. 261, 3, p. 813-823 11 p.

Research output: Contribution to journalArticle

Nude Rats
Head and Neck Neoplasms
Heterografts
Neoplasms
Tumor Burden
38 Citations (Scopus)
MicroRNAs
Cell Differentiation
Stem Cells
Cell Proliferation
Regeneration
2010
30 Citations (Scopus)

Combination radiofrequency ablation and intravenous radiolabeled liposomal doxorubicin: Imaging and quantification of increased drug delivery to tumors

Head, H. W., Dodd, G. D., Bao, A., Soundararajan, A., Garcia-Rojas, X., Prihoda, T. J., Mcmanus, L. M., Goins, B. A., Santoyo, C. A. & Phillips, W. T., May 2010, In : Radiology. 255, 2, p. 405-414 10 p.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
Neoplasms
Doxorubicin
Radionuclide Imaging
Intravenous Administration

Crimson carrier, a long-acting contrast agent for in vivo near-infrared imaging of injured and diseased muscle

Prajapati, S. I., Martinez, C. O., Abraham, J., Mccleish, A. T., Michalek, J. E., Mcmanus, L. M., Rubin, B. P., Shireman, P. K. & Keller, C., Aug 2010, In : Muscle and Nerve. 42, 2, p. 245-251 7 p.

Research output: Contribution to journalArticle

Contrast Media
Muscles
Pharmacokinetics
Neoplasms
Fluorescent Dyes
70 Citations (Scopus)
CCR2 Receptors
Chemokines
Chemokine CCL2
Regeneration
Skeletal Muscle
2009
68 Citations (Scopus)

Bone marrow-derived cell regulation of skeletal muscle regeneration

Sun, D., Martinez, C. O., Ochoa, O., Ruiz-Willhite, L., Bonilla, J. R., Centonze, V. E., Waite, L. L., Michalek, J. E., Mcmanus, L. M. & Shireman, P. K., Feb 2009, In : FASEB Journal. 23, 2, p. 382-395 14 p.

Research output: Contribution to journalArticle

CCR2 Receptors
Bone Marrow Cells
Muscle
Regeneration
Bone
51 Citations (Scopus)

Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity

Lustgarten, M. S., Jang, Y. C., Liu, Y., Muller, F. L., Qi, W., Steinhelper, M., Brooks, S. V., Larkin, L., Shimizu, T., Shirasawa, T., Mcmanus, L. M., Bhattacharya, A., Richardson, A. & Van Remmen, H., 2009, In : American Journal of Physiology - Cell Physiology. 297, 6

Research output: Contribution to journalArticle

Skeletal Muscle Fibers
Superoxide Dismutase
Oxidative Stress
Exercise
Muscles
23 Citations (Scopus)

Near-infrared imaging of injured tissue in living subjects using IR-820

Keller, C., Prajapati, S. I., Martinez, C. O., Bahadur, A. N., Wu, I. Q., Zheng, W., Lechleiter, J. D., Mcmanus, L. M., Chisholm, G. B., Michalek, J. E. & Shireman, P. K., Jan 2009, In : Molecular Imaging. 8, 1, p. 45-54 10 p.

Research output: Contribution to journalArticle

Infrared imaging
Tissue
Contrast Media
lymphatic system
muscles
209 Citations (Scopus)
Microarray Analysis
MicroRNAs
Polymerase Chain Reaction
Reverse Transcription
Complementary DNA
2008
22 Citations (Scopus)

Imaging of 186Re-liposome therapy in ovarian cancer xenograft model of peritoneal carcinomatosis

Zavaleta, C., Goins, B., Bao, A., Mcmanus, L. M., Mcmahan, C. A. & Phillips, W. T., 2008, In : Journal of Drug Targeting. 16, 7-8, p. 626-637 12 p.

Research output: Contribution to journalArticle

Avidin
Biotin
Heterografts
Liposomes
Ovarian Neoplasms

Mission, leadership, and scientific discovery: Looking to the future

Mcmanus, L. M., Sep 2008, In : American Journal of Pathology. 173, 3, p. 599 1 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

The Journal of Molecular Diagnostics: From conception to contract

Kant, J. A. & Mcmanus, L. M., Nov 2008, In : Journal of Molecular Diagnostics. 10, 6, p. 478-479 2 p.

Research output: Contribution to journalArticle

Molecular Pathology
2007
6 Citations (Scopus)

Characterization of an intraperitoneal ovarian cancer xenograft model in nude rats using noninvasive microPET imaging

Zavaleta, C. L., Phillips, W. T., Bradley, Y. C., Mcmanus, L. M., Jerabek, P. A. & Goins, B. A., Mar 2007, In : International Journal of Gynecological Cancer. 17, 2, p. 407-417 11 p.

Research output: Contribution to journalArticle

Nude Rats
Heterografts
Ovarian Neoplasms
Fluorodeoxyglucose F18
Neoplasms
100 Citations (Scopus)
CCR2 Receptors
Vascular Endothelial Growth Factor A
Regeneration
Skeletal Muscle
Muscles
100 Citations (Scopus)

Fat accumulation with altered inflammation and regeneration in skeletal muscle of CCR2-/- mice following ischemic injury

Contreras-Shannon, V., Ochoa, O., Reyes-Reyna, S. M., Sun, D., Michalek, J. E., Kuziel, W. A., Mcmanus, L. M. & Shireman, P. K., Feb 2007, In : American Journal of Physiology - Cell Physiology. 292, 2

Research output: Contribution to journalArticle

CCR2 Receptors
Muscle
Regeneration
Skeletal Muscle
Fats
135 Citations (Scopus)

MCP-1 deficiency causes altered inflammation with impaired skeletal muscle regeneration

Shireman, P. K., Contreras-Shannon, V., Ochoa, O., Karia, B. P., Michalek, J. E. & Mcmanus, L. M., Mar 1 2007, In : Journal of Leukocyte Biology. 81, 3, p. 775-785 11 p.

Research output: Contribution to journalArticle

Regeneration
Skeletal Muscle
Inflammation
Femoral Artery
Macrophages
23 Citations (Scopus)

Oxidation and structural perturbation of redox-sensitive enzymes in injured skeletal muscle

Pierce, A. P., de Waal, E., Mcmanus, L. M., Shireman, P. K. & Chaudhuri, A. R., Dec 15 2007, In : Free Radical Biology and Medicine. 43, 12, p. 1584-1593 10 p.

Research output: Contribution to journalArticle

Cardiotoxins
Oxidation-Reduction
Muscle
Skeletal Muscle
Oxidation
2006
43 Citations (Scopus)

MCP-1 Parallels Inflammatory and Regenerative Responses in Ischemic Muscle

Shireman, P. K., Contreras-Shannon, V., Reyes-Reyna, S. M., Robinson, S. C. & Mcmanus, L. M., Jul 2006, In : Journal of Surgical Research. 134, 1, p. 145-157 13 p.

Research output: Contribution to journalArticle

Chemokine CCL2
Muscles
Regeneration
Femoral Artery
Wounds and Injuries
300 Citations (Scopus)

Peri-implant inflammation defined by the implant-abutment interface

Broggini, N., Mcmanus, L. M., Hermann, J. S., Medina, R., Schenk, R. K., Buser, D. & Cochran, D. L., May 2006, In : Journal of Dental Research. 85, 5, p. 473-478 6 p.

Research output: Contribution to journalArticle

Neutrophils
Inflammation
Bone and Bones
Alveolar Bone Loss
Cell Count
2003
15 Citations (Scopus)

[99mTc] Liposomes for localizing experimental colitis in a rabbit model

Awasthi, V., Goins, B., Mcmanus, L. M., Klipper, R. & Phillips, W. T., Feb 2003, In : Nuclear Medicine and Biology. 30, 2, p. 159-168 10 p.

Research output: Contribution to journalArticle

Colitis
Liposomes
Rabbits
Colon
Inflammatory Bowel Diseases
267 Citations (Scopus)

Persistent acute inflammation at the implant-abutment interface

Broggini, N., Mcmanus, L. M., Hermann, J. S., Medina, R. U., Oates, T. W., Schenk, R. K., Buser, D., Mellonig, J. T. & Cochran, D. L., Mar 2003, In : Journal of Dental Research. 82, 3, p. 232-237 6 p.

Research output: Contribution to journalArticle

Inflammation
Bone and Bones
Mandible
Neutrophils
Dogs
2001
84 Citations (Scopus)

Agonist-dependent failure of neutrophil function in diabetes correlates with extent of hyperglycemia

Mcmanus, L. M., Bloodworth, R. C., Prihoda, T. J., Blodgett, J. L. & Pinckard, R. N., 2001, In : Journal of Leukocyte Biology. 70, 3, p. 395-404 10 p.

Research output: Contribution to journalArticle

methionyl-leucyl-phenylalanine
Leukotriene B4
Platelet Activating Factor
Hyperglycemia
Neutrophils
2000
50 Citations (Scopus)

PAF, a putative mediator of oral inflammation

Mcmanus, L. M. & Pinckard, R. N., 2000, In : Critical Reviews in Oral Biology and Medicine. 11, 2, p. 240-258 19 p.

Research output: Contribution to journalArticle

Inflammation Mediators
Phospholipids
Saliva
Mouth Diseases
1-Alkyl-2-acetylglycerophosphocholine Esterase
1998
2 Citations (Scopus)

Pagetic osteoclasts formed in vitro: Absence of paracrystalline inclusions

Roodman, G. D., Ohsaki, Y., Miller, M. M., Demulder, A., Hosking, D., Singer, F. R. & Mcmanus, L. M., Apr 1998, In : Journal of Submicroscopic Cytology and Pathology. 30, 2, p. 315-327 13 p.

Research output: Contribution to journalArticle

Osteoclasts
Nucleocapsid
Distemper
Bone and Bones
Intranuclear Inclusion Bodies
1996

Differential cardiovascular alterations induced by individual molecular species of PAF

Bloodworth, R., Deavers, S. I. & Mcmanus, L. M., 1996, In : FASEB Journal. 10, 6

Research output: Contribution to journalArticle

indomethacin
Indomethacin
Carbon Monoxide
Phosphorylcholine
hypotension

PAF-induced pulmonary eosinophil recruitment in the rabbit

Meadows, R. L., Bloodworth, R. & Mcmanus, L. M., 1996, In : FASEB Journal. 10, 6

Research output: Contribution to journalArticle

platelet-activating factor
Platelet Activating Factor
eosinophils
Eosinophils
rabbits
1995
6 Citations (Scopus)

Lipid inhibitors of platelet-activating factor (PAF) in normal human plasma

Woodard, D. S., Ostrom, K. K. & Mcmanus, L. M., 1995, In : Journal of Lipid Mediators and Cell Signalling. 12, 1, p. 11-28 18 p.

Research output: Contribution to journalArticle

Plasma (human)
Platelet Activating Factor
Lipids
Platelets
Phospholipids
5 Citations (Scopus)
Platelet Activating Factor
Saliva
Spectrum analysis
pentafluorobenzoic anhydride
Phospholipids
23 Citations (Scopus)

Salivary PAF levels correlate with the severity of periodontal inflammation.

Garito, M. L., Prihoda, T. J. & Mcmanus, L. M., Apr 1995, In : Journal of Dental Research. 74, 4, p. 1048-1056 9 p.

Research output: Contribution to journalArticle

Platelet Activating Factor
Inflammation
Saliva
Phospholipids
Autacoids
27 Citations (Scopus)

Structural and (Patho)physiological diversity of PAF

Pinckard, R. N., Woodard, D. S., Showell, H. J., Conklyn, M. J., Novak, M. J. & Mcmanus, L. M., Dec 1995, In : Clinical Reviews in Allergy. 12, 4, p. 329-359 31 p.

Research output: Contribution to journalArticle

Platelet Activating Factor
Structure-Activity Relationship
18 Citations (Scopus)

The effect of initial periodontal therapy on salivary platelet-activating factor levels in chronic adult periodontitis.

Rasch, M. S., Mealey, B. L., Prihoda, T. J., Woodard, D. S. & Mcmanus, L. M., Jul 1995, In : Journal of Periodontology. 66, 7, p. 613-623 11 p.

Research output: Contribution to journalArticle

Chronic Periodontitis
Platelet Activating Factor
Root Planing
Saliva
Therapeutics
1993
76 Citations (Scopus)

PAF molecular heterogeneity: Pathobiological implications

Mcmanus, L. M., Woodard, D. S., Deavers, S. I. & Pinckard, R. N., 1993, In : Laboratory Investigation. 69, 6, p. 639-650 12 p.

Research output: Contribution to journalArticle

Autacoids
Platelet Activating Factor
Phospholipids
Research Personnel
In Vitro Techniques
18 Citations (Scopus)

Radiation-induced increased platelet-activating factor activity in mixed saliva

Mcmanus, L. M., Ostrom, K. K., Lear, C., Luce, E. B., Gander, D. L., Pinckard, R. N. & Redding, S. W., 1993, In : Laboratory Investigation. 68, 1, p. 118-124 7 p.

Research output: Contribution to journalArticle

Platelet Activating Factor
Saliva
Radiation
Mucositis
Phospholipids
1992
23 Citations (Scopus)

Differential responsiveness of human neutrophils to the autocrine actions of 1-O-alkyl-homologs and 1-acyl analogs of platelet-activating factor

Pinckard, R. N., Showell, H. J., Castillo, R., Lear, C., Breslow, R., Mcmanus, L. M., Woodard, D. S. & Ludwig, J. C., Jun 1 1992, In : Journal of Immunology. 148, 11, p. 3528-3535 8 p.

Research output: Contribution to journalArticle

Platelet Activating Factor
Phosphorylcholine
Neutrophils
Enzymes
Chemotaxis
1991
5 Citations (Scopus)

Cardiopulmonary and intravascular alterations during the sustained infusion of PAF

Deavers, S. I., Arroyave, J. M., Prihoda, T. J. & Mcmanus, L. M., 1991, In : Journal of Lipid Mediators. 4, 2, p. 145-163 19 p.

Research output: Contribution to journalArticle

Platelet Activating Factor
Lung
Arterial Pressure
Hypertension
Lung Compliance
1990
11 Citations (Scopus)

Anatomic basis for species differences in peripheral lung strip contraction to PAF

Halonen, M., Dunn, A. M., Palmer, J. D. & Mcmanus, L. M., 1990, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 259, 2 3-1

Research output: Contribution to journalArticle

Platelet Activating Factor
Lung
Guinea Pigs
Leukotriene D4
Histamine
67 Citations (Scopus)

Atypical multinucleated cells form in long-term marrow cultures from patients with Paget's disease

Kukita, A., Chenu, C., Mcmanus, L. M., Mundy, G. R. & Roodman, G. D., Apr 1990, In : Journal of Clinical Investigation. 85, 4, p. 1280-1286 7 p.

Research output: Contribution to journalArticle

Osteoclasts
Bone Marrow
Ergocalciferols
Bone and Bones
Cell Nucleus
14 Citations (Scopus)

Deficiency of salivary PAF in edentulous individuals.

Mcmanus, L. M., Marze, B. T. & Schiess, A. V., Nov 1990, In : Journal of Periodontal Research. 25, 6, p. 347-351 5 p.

Research output: Contribution to journalArticle

Saliva
Phosphorylcholine
Inflammation Mediators
Biological Assay
Phospholipids
1989
41 Citations (Scopus)

Osteoclast-like cells formed in long-term human bone marrow cultures express a similar surface phenotype as authentic osteoclasts

Kukita, T., Mcmanus, L. M., Miller, M., Civin, C. & Roodman, G. D., 1989, In : Laboratory Investigation. 60, 4, p. 532-538 7 p.

Research output: Contribution to journalArticle

Osteoclasts
Bone Marrow
Phenotype
Antigens
Bone and Bones
61 Citations (Scopus)

Osteoclast-like cells form in long-term human bone marrow but not in peripheral blood cultures

Takahashi, N., Kukita, T., MacDonald, B. R., Bird, A., Mundy, G. R., Mcmanus, L. M., Miller, M., Boyde, A., Jones, S. J. & Roodman, G. D., 1989, In : Journal of Clinical Investigation. 83, 2, p. 543-550 8 p.

Research output: Contribution to journalArticle

Osteoclasts
Bone Marrow
Monocytes
Sperm Whale
Blood Culture
13 Citations (Scopus)

Platelet activating factor in pulmonary pathobiology

Mcmanus, L. M. & Deavers, S. I., 1989, In : Clinics in Chest Medicine. 10, 1, p. 107-118+ix

Research output: Contribution to journalArticle

Platelet Activating Factor
Lung
Phospholipids
Inflammation Mediators
Bronchoconstriction