Research output per year
Research output per year
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Dive into the research topics where Kristin E Cano is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain
Clark, N. E., Katolik, A., Gallant, P., Welch, A., Murphy, E., Buerer, L., Schorl, C., Naik, N., Naik, M. T., Holloway, S. P., Cano, K., Weintraub, S. T., Howard, K. M., Hart, P. J., Jogl, G., Damha, M. J. & Fairbrother, W. G., Sep 2023, In: Journal of Biological Chemistry. 299, 9, 105100.Research output: Contribution to journal › Article › peer-review
Open Access -
Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer
Afsar, M., Liu, G. Q., Jia, L., Ruben, E. A., Nayak, D., Sayyad, Z., Bury, P. D. S., Cano, K. E., Nayak, A., Zhao, X. R., Shukla, A., Sung, P., Wasmuth, E. V., Gack, M. U. & Olsen, S. K., Dec 2023, In: Nature communications. 14, 1, 4786.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6
Yuan, L., Gao, F., Lv, Z., Nayak, D., Nayak, A., Santos Bury, P. D., Cano, K. E., Jia, L., Oleinik, N., Atilgan, F. C., Ogretmen, B., Williams, K. M., Davies, C., El Oualid, F., Wasmuth, E. V. & Olsen, S. K., Dec 2022, In: Nature communications. 13, 1, 4880.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Targeting SARS-CoV-2 Proteases for COVID-19 Antiviral Development
Lv, Z., Cano, K. E., Jia, L., Drag, M., Huang, T. T. & Olsen, S. K., Feb 3 2022, In: Frontiers in Chemistry. 9, 819165.Research output: Contribution to journal › Review article › peer-review
Open Access54 Scopus citations -
Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification
Yu, C. H., Bhattacharya, A., Persaud, M., Taylor, A. B., Wang, Z., Bulnes-Ramos, A., Xu, J., Selyutina, A., Martinez-Lopez, A., Cano, K., Demeler, B., Kim, B., Hardies, S. C., Diaz-Griffero, F. & Ivanov, D. N., Dec 1 2021, In: Nature communications. 12, 1, 731.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations
Datasets
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Crystal structure of mithramycin analogue MTM SA-Phe in complex with a 10-mer DNA AGGGTACCCT
Hou, C. (Contributor), Weidenbach, S. (Contributor), Cano, K. E. (Contributor), Wang, Z. (Contributor), Mitra, P. (Contributor), Ivanov, D. N. (Contributor), Rohr, J. (Contributor) & Tsodikov, O. V. (Contributor), Protein Data Bank (PDB), Sep 14 2016
DOI: 10.2210/pdb5JW0/pdb, https://www.wwpdb.org/pdb?id=pdb_00005jw0
Dataset
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Crystal structure of mithramycin analogue MTM SA-Phe in complex with a 10-mer DNA AGGGATCCCT
Hou, C. (Contributor), Weidenbach, S. (Contributor), Cano, K. E. (Contributor), Wang, Z. (Contributor), Mitra, P. (Contributor), Ivanov, D. N. (Contributor), Rohr, J. (Contributor) & Tsodikov, O. V. (Contributor), Protein Data Bank (PDB), Sep 14 2016
DOI: 10.2210/pdb5JW2/pdb, https://www.wwpdb.org/pdb?id=pdb_00005jw2
Dataset
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Derivative of mouse TGF-beta2, with a deletion of residues 52-71 and K25R, R26K, L51R, A74K, C77S, L89V, I92V, K94R T95K, I98V single amino acid substitutions, bound to human TGF-beta type II receptor ectodomain residues 15-130
Kim, S. K. (Contributor), Barron, L. (Contributor), Hinck, C. S. (Contributor), Petrunak, E. M. (Contributor), Cano, K. E. (Contributor), Thangirala, A. (Contributor), Iskra, B. (Contributor), Brothers, M. (Contributor), Vonberg, M. (Contributor), Leal, B. (Contributor), Richter, B. (Contributor), Kodali, R. (Contributor), Taylor, A. B. (Contributor), Du, S. (Contributor), Barnes, C. O. (Contributor), Sulea, T. (Contributor), Calero, G. (Contributor), Hart, P. J. (Contributor), Hart, M. J. (Contributor), Demeler, B. (Contributor) & Hinck, A. P. (Contributor), Protein Data Bank (PDB), Mar 1 2017
DOI: 10.2210/pdb5TX4/pdb, https://www.wwpdb.org/pdb?id=pdb_00005tx4
Dataset
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Human SAMHD1 bound to deoxyribo(C*G*C*C*T)-oligonucleotide
Yu, C. H. (Contributor), Bhattacharya, A. (Contributor), Persaud, M. (Contributor), Taylor, A. B. (Contributor), Wang, Z. (Contributor), Bulnes-Ramos, A. (Contributor), Xu, J. (Contributor), Selyutina, A. (Contributor), Martinez-Lopez, A. (Contributor), Cano, K. (Contributor), Demeler, B. (Contributor), Kim, B. (Contributor), Hardies, S. C. (Contributor), Diaz-Griffero, F. (Contributor) & Ivanov, D. N. (Contributor), Protein Data Bank (PDB), Sep 2 2020
DOI: 10.2210/pdb6U6X/pdb, https://www.wwpdb.org/pdb?id=pdb_00006u6x
Dataset
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Crystal Structures of the bispecific ubiquitin/FAT10 activating enzyme, Uba6
Yuan, L. (Contributor), Gao, F. (Contributor), Lv, Z. (Contributor), Nayak, D. (Contributor), Nayak, A. (Contributor), Santos Bury, P. D. (Contributor), Cano, K. E. (Contributor), Jia, L. (Contributor), Oleinik, N. (Contributor), Atilgan, F. C. (Contributor), Ogretmen, B. (Contributor), Williams, K. M. (Contributor), Davies, C. (Contributor), El Oualid, F. (Contributor), Wasmuth, E. V. (Contributor) & Olsen, S. K. (Contributor), Protein Data Bank (PDB), Nov 2 2022
DOI: 10.2210/pdb7SOL/pdb, https://www.wwpdb.org/pdb?id=pdb_00007sol
Dataset