John Sarantopoulos

  • 1520 Citations
  • 21 h-Index
1991 …2019
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  • 1 Similar Profiles
Pharmacokinetics Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Safety Medicine & Life Sciences
Tumors Chemical Compounds
Maximum Tolerated Dose Medicine & Life Sciences
Aurora Kinase A Medicine & Life Sciences
Liver Medicine & Life Sciences
docetaxel Medicine & Life Sciences

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Projects 1991 2019

INSTITUTE FOR CANCER RESEARCH AND CARE

Hinck, A. P., Sarantopoulos, J., Curiel, T. J., Lafer, E. M., Weintraub, S. E., Karnad, A. B., Lechleiter, J. D., Thompson, I. M., Leach, R. J., Christy, B. A., Allred, C., Johnson, K., Padmanabhan, S., I-Tien, Y., Naylor, S., Gazitt, Y., Pollock, B. H., Mundy, G., Bonewald, L., Davis, S., Lee, E., Oishi, N., Hasty, E., Vijg, J. N. M. N., Herman, B. A., Johnson, K., Moyer, M., Windle, J., McGill, J., O'Connell, P., Clark, G., Kuhn, J., Wolf, R., Allred, D. C., Weiss, G., Boldt, D., Coltman, C. & Huang, H.

National Institutes of Health

9/1/917/31/19

Project: Research project

Neoplasms
Research
Health
Hispanic Americans
Financial Management

Research Output 1996 2019

  • 1520 Citations
  • 21 h-Index
  • 59 Article
  • 1 Comment/debate
1 Citation (Scopus)

A phase II, multicenter, single-arm study of mipsagargin (G-202) as a second-line therapy following sorafenib for adult patients with progressive advanced hepatocellular carcinoma

Mahalingam, D., Peguero, J., Cen, P., Arora, S. P., Sarantopoulos, J., Rowe, J., Allgood, V., Tubb, B. & Campos, L., Jun 1 2019, In : Cancers. 11, 6, 833.

Research output: Contribution to journalArticle

Open Access
Hepatocellular Carcinoma
Disease-Free Survival
Disease Progression
Neoplasms
Magnetic Resonance Imaging

Pharmacokinetics of the Investigational Aurora A Kinase Inhibitor Alisertib in Adult Patients With Advanced Solid Tumors or Relapsed/Refractory Lymphoma With Varying Degrees of Hepatic Dysfunction

Zhou, X., Lockhart, A. C., Fu, S., Nemunaitis, J., Sarantopoulos, J., Muehler, A., Rangachari, L., Bargfrede, M. & Venkatakrishnan, K., Jan 1 2019, In : Journal of Clinical Pharmacology.

Research output: Contribution to journalArticle

Aurora Kinase A
Lymphoma
Pharmacokinetics
Liver
Neoplasms

Pharmacokinetic study of osimertinib in cancer patients with mild or moderate hepatic impairment

Grande, E., Donald Harvey, R., You, B., Batlle, J. F., Galbraith, H., Sarantopoulos, J., Ramalingam, S. S., Mann, H., So, K., Johnson, M. & Vishwanathan, K., May 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. p. 291-299 9 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Liver
Neoplasms
osimertinib
Safety

Phase 1 open-label, multicenter study of first-in-class RORγ agonist LYC-55716 (Cintirorgon): Safety, tolerability, and preliminary evidence of antitumor activity

Mahalingam, D., Wang, J. S., Hamilton, E. P., Sarantopoulos, J., Nemunaitis, J., Weems, G., Carter, L., Hu, X., Schreeder, M. & Wilkins, H. J., Jun 15 2019, In : Clinical Cancer Research. 25, 12, p. 3508-3516 9 p.

Research output: Contribution to journalArticle

Open Access
Multicenter Studies
Safety
Pharmacokinetics
Anemia
Hypophosphatemia
5 Citations (Scopus)

Evaluation of hepatic impairment on pharmacokinetics and safety of crizotinib in patients with advanced cancer

El-Khoueiry, A. B., Sarantopoulos, J., O’Bryant, C. L., Ciombor, K. K., Xu, H., O’Gorman, M., Chakrabarti, J., Usari, T. & El-Rayes, B. F., Feb 21 2018, (Accepted/In press) In : Cancer Chemotherapy and Pharmacology. p. 1-12 12 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Safety
Liver
Neoplasms
varespladib methyl