• 6089 Citations
  • 44 h-Index
1966 …2019

Research output per year

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Research Output

2019

Disulfide bond of Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin is essential to maintain the ADP-ribosylating and vacuolating activities

Balasubramanian, S., Pandranki, L., Maupin, S., Ramasamy, K., Taylor, A. B., Hart, P. J., Baseman, J. B. & Kannan, T. R., Aug 2019, In : Cellular Microbiology. 21, 8, e13032.

Research output: Contribution to journalEditorial

2 Scopus citations
2018

Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin uses a novel KELED sequence for retrograde transport and subsequent cytotoxicity

Ramasamy, K., Balasubramanian, S., Manickam, K., Pandranki, L., Taylor, A. B., Hart, P. J., Baseman, J. B. & Kannan, T. R., Jan 1 2018, In : mBio. 9, 1, e01663-17.

Research output: Contribution to journalArticle

2 Scopus citations

NLRP3 is a critical regulator of inflammation and innate immune cell response during Mycoplasma pneumoniae infection

Segovia, J. A., Chang, T. H., Winter, V. T., Coalson, J. J., Cagle, M. P., Pandranki, L., Bose, S., Baseman, J. B. & Kannan, T. R., Jan 1 2018, In : Infection and Immunity. 86, 1, e00548-17.

Research output: Contribution to journalArticle

22 Scopus citations

The immunopathologic effects of mycoplasma pneumoniae and community-acquired respiratory distress syndrome toxin a primate model

Maselli, D. J., Medina, J. L., Brooks, E. G., Coalson, J. J., Kannan, T. R., Winter, V. T., Principe, M., Cagle, M. P., Baseman, J. B., Dube, P. H. & Peters, J. I., Feb 2018, In : American journal of respiratory cell and molecular biology. 58, 2, p. 253-260 8 p.

Research output: Contribution to journalEditorial

12 Scopus citations
2017

Mycoplasma pneumoniae and health outcomes in children with asthma

Wood, P. R., Kampschmidt, J. C., Dube, P. H., Cagle, M. P., Chaparro, P., Ketchum, N. S., Kannan, T. R., Singh, H., Peters, J. I., Baseman, J. B. & Brooks, E. G., Aug 2017, In : Annals of Allergy, Asthma and Immunology. 119, 2, p. 146-152.e2

Research output: Contribution to journalArticle

6 Scopus citations

The cryptic plasmid is more important for Chlamydia muridarum to colonize the mouse gastrointestinal tract than to infect the genital tract

Shao, L., Melero, J., Zhang, N., Arulanandam, B., Baseman, J., Liu, Q. & Zhong, G., May 2017, In : PloS one. 12, 5, e0177691.

Research output: Contribution to journalArticle

15 Scopus citations
2016

Intravenous inoculation with chlamydia muridarum leads to a long-lasting infection restricted to the gastrointestinal tract

Dai, J., Zhang, T., Wang, L., Shao, L., Zhu, C., Zhang, Y., Failor, C., Schenken, R., Baseman, J., He, C. & Zhong, G., 2016, In : Infection and immunity. 84, 8, p. 2382-2388 7 p.

Research output: Contribution to journalArticle

19 Scopus citations
2015

Intrauterine infection with plasmid-free Chlamydia muridarum reveals a critical role of the plasmid in chlamydial ascension and establishes a model for evaluating plasmid-independent pathogenicity

Chen, J., Yang, Z., Sun, X., Tang, L., Ding, Y., Xue, M., Zhou, Z., Baseman, J. & Zhong, G., Jan 1 2015, In : Infection and immunity. 83, 6, p. 2583-2592 10 p.

Research output: Contribution to journalArticle

15 Scopus citations

Regulation of TLR3 activation by S100A9

Tsai, S. Y., Segovia, J. A., Chang, T. H., Shil, N. K., Pokharel, S. M., Kannan, T. R., Baseman, J. B., Defrêne, J., Pagé, N., Cesaro, A., Tessier, P. A. & Bose, S., Nov 2015, In : Journal of Immunology. 195, 9, p. 4426-4437 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae

Becker, A., Kannan, T. R., Taylor, A. B., Pakhomova, O. N., Zhang, Y., Somarajan, S. R., Galaleldeen, A., Holloway, S. P., Baseman, J. B. & Hart, P. J., Apr 21 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 16, p. 5165-5170 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
2014

ADP-Ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS toxin regulates inflammasome activity

Bose, S., Segovia, J. A., Somarajan, S. R., Chang, T. H., Kannan, T. R. & Baseman, J. B., Dec 23 2014, In : mBio. 5, 6, e02186-14.

Research output: Contribution to journalArticle

36 Scopus citations

Annexin A2 mediates mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin binding to eukaryotic cells

Somarajan, S. R., Al-Asadi, F., Ramasamy, K., Pandranki, L., Baseman, J. B. & Kannan, T. R., Aug 19 2014, In : mBio. 5, 4, e01497-14.

Research output: Contribution to journalArticle

18 Scopus citations

Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology

Chen, J., Zhang, H., Zhou, Z., Yang, Z., Ding, Y., Zhou, Z., Zhong, E., Arulanandam, B., Baseman, J. & Zhong, G., Apr 1 2014, In : PLoS One. 9, 4, e0095076.

Research output: Contribution to journalArticle

Chlamydial induction of hydrosalpinx in 11 strains of mice reveals multiple host mechanisms for preventing upper genital tract pathology

Chen, J., Zhang, H., Zhou, Z., Yang, Z., Ding, Y., Zhou, Z., Zhong, E., Arulanandam, B., Baseman, J. & Zhong, G., Apr 15 2014, In : PloS one. 9, 4, e95076.

Research output: Contribution to journalArticle

41 Scopus citations

Functional characterization of osmotically inducible protein C (MG_427) from Mycoplasma genitalium

Zhang, W. & Baseman, J. B., Mar 1 2014, In : Journal of Bacteriology. 196, 5, p. 1012-1019 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Functional mapping of community-acquired respiratory distress syndrome (CARDS) toxin of Mycoplasma pneumoniae defines regions with ADP-ribosyltransferase, vacuolating and receptor-binding activities

Kannan, T. R., Krishnan, M., Ramasamy, K., Becker, A., Pakhomova, O. N., Hart, P. J. & Baseman, J. B., Aug 2014, In : Molecular Microbiology. 93, 3, p. 568-581 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

Induction of protective immunity against Chlamydia muridarum intracervical infection in DBA/1j mice

Tang, L., Yang, Z., Zhang, H., Zhou, Z., Arulanandam, B., Baseman, J. & Zhong, G., Mar 10 2014, In : Vaccine. 32, 12, p. 1407-1413 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Lack of long-lasting hydrosalpinx in A/J mice correlates with rapid but transient chlamydial ascension and neutrophil recruitment in the oviduct following intravaginal inoculation with Chlamydia muridarum

Zhang, H., Zhou, Z., Chen, J., Wu, G., Yang, Z., Zhou, Z., Baseman, J., Zhang, J., Reddick, R. L. & Zhong, G., Jul 2014, In : Infection and immunity. 82, 7, p. 2688-2696 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Mycoplasma pneumoniae CARDS toxin exacerbates ovalbumin-induced asthma-like inflammation in BALB/c mice

Medina, J. L., Coalson, J. J., Brooks, E. G., Le Saux, C. J., Winter, V. T., Chaparro, A., Principe, M. F. R., Solis, L., Kannan, T. R., Baseman, J. B. & Dube, P. H., Jul 24 2014, In : PloS one. 9, 7, e102613.

Research output: Contribution to journalArticle

17 Scopus citations

Plasmid-encoded Pgp3 is a major virulence factor for Chlamydia muridarum to induce hydrosalpinx in mice

Liu, Y., Huang, Y., Yang, Z., Sun, Y., Gong, S., Hou, S., Chen, C., Li, Z., Liu, Q., Wu, Y., Baseman, J. & Zhong, G., Jan 1 2014, In : Infection and Immunity. 82, 12, p. 5327-5335 9 p.

Research output: Contribution to journalArticle

59 Scopus citations

Reduced live organism recovery and lack of hydrosalpinx in mice infected with plasmid-free Chlamydia muridarum

Lei, L., Chen, J., Hou, S., Ding, Y., Yang, Z., Zeng, H., Baseman, J. & Zhong, G., Mar 1 2014, In : Infection and Immunity. 82, 3, p. 983-992 10 p.

Research output: Contribution to journalArticle

50 Scopus citations

Transformation of Chlamydia muridarum reveals a role for Pgp5 in suppression of plasmid-dependent gene expression

Liu, Y., Chen, C., Gong, S., Hou, S., Qi, M., Liu, Q., Baseman, J. & Zhong, G., Mar 1 2014, In : Journal of bacteriology. 196, 5, p. 989-998 10 p.

Research output: Contribution to journalArticle

47 Scopus citations
2013

Mycoplasma: Curiosity and pathogen

Baseman, J. B. & Waites, K. B., Jul 8 2013, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 308-313 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Mycoplasma pneumoniae CARDS Toxin Is Internalized via Clathrin-Mediated Endocytosis

Krishnan, M., Kannan, T. R. & Baseman, J. B., May 7 2013, In : PloS one. 8, 5, e62706.

Research output: Contribution to journalArticle

22 Scopus citations

Mycoplasma pneumoniae in children with acute and refractory asthma

Wood, P. R., Hill, V. L., Burks, M. L., Peters, J. I., Singh, H., Kannan, T. R., Vale, S., Cagle, M. P., Principe, M. F. R., Baseman, J. B. & Brooks, E. G., May 2013, In : Annals of Allergy, Asthma and Immunology. 110, 5, p. 328-334.e1

Research output: Contribution to journalArticle

55 Scopus citations

Oviduct Infection and Hydrosalpinx in DBA1/j Mice Is Induced by Intracervical but Not Intravaginal Inoculation with Chlamydia muridarum

Tang, L., Zhang, H., Lei, L., Gong, S., Zhou, Z., Baseman, J. & Zhong, G., Aug 5 2013, In : PloS one. 8, 8, e71649.

Research output: Contribution to journalArticle

35 Scopus citations
2012

Fatal outcomes in family transmission of mycoplasma pneumoniae

Kannan, T. R., Hardy, R. D., Coalson, J. J., Cavuoti, D. C., Siegel, J. D., Cagle, M., Musatovova, O., Herrera, C. & Baseman, J. B., Jan 15 2012, In : Clinical Infectious Diseases. 54, 2, p. 225-231 7 p.

Research output: Contribution to journalArticle

28 Scopus citations

Mycoplasma: Curiosity and pathogen

Baseman, J. B. & Waites, K. B., May 15 2012, Schaechter's Mechanisms of Microbial Disease: Fifth Edition. Wolters Kluwer Health Adis (ESP), p. 308-313 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Mycoplasma pneumoniae CARDS toxin induces pulmonary eosinophilic and lymphocytic inflammation

Medina, J. L., Coalson, J. J., Brooks, E. G., Winter, V. T., Chaparro, A., Principe, M. F. R., Kannan, T. R., Baseman, J. B. & Dube, P. H., Jun 2012, In : American journal of respiratory cell and molecular biology. 46, 6, p. 815-822 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Mycoplasma pneumoniae Large DNA Repetitive Elements RepMP1 Show Type Specific Organization among Strains

Musatovova, O., Kannan, T. R. & Baseman, J. B., Oct 16 2012, In : PloS one. 7, 10, e47625.

Research output: Contribution to journalArticle

8 Scopus citations
2011

Cellular vacuoles induced by Mycoplasma pneumoniae cards toxin originate from Rab9-Associated compartments

Johnson, C., Kannan, T. R. & Baseman, J. B., 2011, In : PloS one. 6, 7, e22877.

Research output: Contribution to journalArticle

26 Scopus citations

Efficacy of increasing dosages of clarithromycin for treatment of experimental Mycoplasma pneumoniae pneumonia

Tagliabue, C., Techasaensiri, C., Torres, J. P., Katz, K., Meek, C., Kannan, T. R., Coalson, J. J., Esposito, S., Principi, N., Leff, R., Baseman, J. B. & Hardy, R. D., Oct 2011, In : Journal of Antimicrobial Chemotherapy. 66, 10, p. 2323-2329 7 p., dkr306.

Research output: Contribution to journalArticle

10 Scopus citations

Novel toxin assays implicate Mycoplasma pneumoniae in prolonged ventilator course and hypoxemia

Muir, M. T., Cohn, S. M., Louden, C., Kannan, T. R. & Baseman, J. B., Feb 1 2011, In : Chest. 139, 2, p. 305-310 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Persistence of community-acquired respiratory distress syndrome toxin-producing Mycoplasma pneumoniae in refractory asthma

Peters, J., Singh, H., Brooks, E. G., Diaz, J., Kannan, T. R., Coalson, J. J., Baseman, J. G., Cagle, M. & Baseman, J. B., Aug 1 2011, In : Chest. 140, 2, p. 401-407 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

Synthesis and distribution of CARDS toxin during mycoplasma pneumoniae infection in a murine model

Kannan, T. R., Coalson, J. J., Cagle, M., Musatovova, O., Hardy, R. D. & Baseman, J. B., Nov 15 2011, In : Journal of Infectious Diseases. 204, 10, p. 1596-1604 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Transcriptional regulation of MG-149, an osmoinducible lipoprotein gene from Mycoplasma genitalium

Zhang, W. & Baseman, J. B., Jul 2011, In : Molecular Microbiology. 81, 2, p. 327-339 13 p.

Research output: Contribution to journalArticle

19 Scopus citations

Transcriptional response of Mycoplasma genitalium to osmotic stress

Zhang, W. & Baseman, J. B., Feb 2011, In : Microbiology. 157, 2, p. 548-556 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
2010

Crystallization of community-acquired respiratory distress syndrome toxin from Mycoplasma pneumoniae

Pakhomova, O. N., Taylor, A. B., Becker, A., Holloway, S. P., Kannan, T. R., Baseman, J. B. & Hart, P. J., 2010, In : Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 66, 3, p. 294-296 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Molecular cloning, expression, and characterization of a Ca 2+-dependent, membrane-associated nuclease of Mycoplasma genitalium

Li, L., Krishnan, M., Baseman, J. B. & Kannan, T. R., Oct 2010, In : Journal of bacteriology. 192, 19, p. 4876-4884 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Mycoplasma genitalium symptoms, concordance and treatment in high-risk sexual dyads

Thurman, A. R., Musatovova, O., Perdue, S., Shain, R. N., Baseman, J. G. & Baseman, J. B., Mar 2010, In : International Journal of STD and AIDS. 21, 3, p. 177-183 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Mycoplasma pneumoniae Community Acquired Respiratory Distress Syndrome toxin expression reveals growth phase and infection-dependent regulation

Kannan, T. R., Musatovova, O., Balasubramanian, S., Cagle, M., Jordan, J. L., Krunkosky, T. M., Davis, A., Hardy, R. D. & Baseman, J. B., Jun 2010, In : Molecular Microbiology. 76, 5, p. 1127-1141 15 p.

Research output: Contribution to journalArticle

37 Scopus citations
26 Scopus citations

Variation in colonization, ADP-ribosylating and vacuolating cytotoxin, and pulmonary disease severity among Mycoplasma pneumoniae strains

Techasaensiri, C., Tagliabue, C., Cagle, M., Iranpour, P., Katz, K., Kannan, T. R., Coalson, J. J., Baseman, J. B. & Hardy, R. D., Sep 15 2010, In : American Journal of Respiratory and Critical Care Medicine. 182, 6, p. 797-804 8 p.

Research output: Contribution to journalArticle

35 Scopus citations
2009

A chlamydial type III-secreted effector protein (Tarp) is predominantly recognized by antibodies from humans infected with Chlamydia trachomatis and induces protective immunity against upper genital tract pathologies in mice

Wang, J., Chen, L., Chen, F., Zhang, X., Zhang, Y., Baseman, J., Perdue, S., Yeh, I. T., Shain, R., Holland, M., Bailey, R., Mabey, D., Yu, P. & Zhong, G., May 14 2009, In : Vaccine. 27, 22, p. 2967-2980 14 p.

Research output: Contribution to journalArticle

46 Scopus citations

Amino acid changes in elongation factor Tu of Mycoplasma pneumoniae and Mycoplasma genitalium influence fibronectin binding

Balasubramanian, S., Kannan, T. R., Hart, P. J. & Baseman, J. B., Sep 2009, In : Infection and immunity. 77, 9, p. 3533-3541 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Analysis identifying common and distinct sequences among Texas clinical strains of Mycoplasma genitalium

Musatovova, O. & Baseman, J. B., May 1 2009, In : Journal of clinical microbiology. 47, 5, p. 1469-1475 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Analysis of pulmonary inflammation and function in the mouse and baboon after exposure to Mycoplasma pneumoniae CARDS toxin

Hardy, R. D., Coalson, J. J., Peters, J., Chaparro, A., Techasaensiri, C., Cantwell, A. M., Kannan, T. R., Baseman, J. B. & Dube, P. H., Oct 27 2009, In : PloS one. 4, 10, e7562.

Research output: Contribution to journalArticle

60 Scopus citations

Characterization of a unique ADP-ribosyltransferase of Mycoplasma penetrans

Johnson, C., Kannan, T. R. & Baseman, J. B., Oct 2009, In : Infection and immunity. 77, 10, p. 4362-4370 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Characterization of a unique ADP-ribosyltransferase of Mycoplasma penetrans (Infection and Immunity (2009) 77, 10 (4362-4370))

Johnson, C., Kannan, T. R. & Baseman, J. B., Dec 1 2009, In : Infection and immunity. 77, 12, 1 p.

Research output: Contribution to journalComment/debate

Mycoplasma antigens as a possible trigger for the induction of antimitochondrial antibodies in primary biliary cirrhosis

Berg, C. P., Kannan, T. R., Klein, R., Gregor, M., Baseman, J. B., Wesselborg, S., Lauber, K. & Stein, G. M., 2009, In : Liver International. 29, 6, p. 797-809 13 p.

Research output: Contribution to journalArticle

34 Scopus citations