James D Stockand

  • 3945 Citations
  • 41 h-Index
1993 …2020

Research output per year

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Research Output

2020

Comparative study of the in vivo toxicity and pathophysiology of envenomation by three medically important Egyptian snake venoms

Abd El-Aziz, T. M., Shoulkamy, M. I., Hegazy, A. M., Stockand, J. D., Mahmoud, A. & Mashaly, A. M. A., Jan 1 2020, In : Archives of Toxicology. 94, 1, p. 335-344 10 p.

Research output: Contribution to journalArticle

2019

Liddle’s syndrome mechanisms, diagnosis and management

Enslow, B. T., Stockand, J. D. & Berman, J. M., Jan 1 2019, In : Integrated Blood Pressure Control. 12, p. 13-22 10 p.

Research output: Contribution to journalReview article

Open Access
2 Scopus citations

Snake Venoms in Drug Discovery: Valuable Therapeutic Tools for Life Saving

Mohamed Abd El-Aziz, T., Garcia Soares, A. & Stockand, J. D., Sep 25 2019, In : Toxins. 11, 10

Research output: Contribution to journalReview article

Open Access
2 Scopus citations
2018

Collecting duct principal, but not intercalated, cell prorenin receptor regulates renal sodium and water excretion

Ramkumar, N., Stuart, D., Mironova, E., Abraham, N., Gao, Y., Wang, S., Lakshmipathi, J., Stockand, J. D. & Kohan, D. E., Sep 1 2018, In : American Journal of Physiology - Renal Physiology. 315, 3, p. F607-F617

Research output: Contribution to journalArticle

7 Scopus citations

Physiological regulation of the epithelial Na + channel by casein kinase II

Berman, J. M., Mironova, E. & Stockand, J. D., Mar 2018, In : American Journal of Physiology - Renal Physiology. 314, 3, p. F367-F372

Research output: Contribution to journalArticle

2 Scopus citations
2017

Collecting duct nitric oxide synthase 1ß activation maintains sodium homeostasis during high sodium intake through suppression of aldosterone and renal angiotensin II pathways

Hyndman, K. A., Mironova, E. V., Giani, J. F., Dugas, C., Collins, J., McDonough, A. A., Stockand, J. D. & Pollock, J. S., Oct 1 2017, In : Journal of the American Heart Association. 6, 10, e006896.

Research output: Contribution to journalArticle

4 Scopus citations

ENaC activity in the cortical collecting duct of HKα1 H+, K+-ATPase knockout mice is uncoupled from Na+ intake

Mironova, E., Jeanette Lynch, I., Berman, J. M., Gumz, M. L., Stockand, J. D. & Wingo, C. S., Jan 1 2017, In : American Journal of Physiology - Renal Physiology. 312, 6, p. F1073-F1080

Research output: Contribution to journalArticle

2 Scopus citations

Loop diuretics are K+-sparing in the presence of a low-Na+, high-K+ diet

Boiko, N., Berman, J., Mironova, E. & Stockand, J. D., Oct 1 2017, In : Kidney International. 92, 4, p. 786-787 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

TrpA1 activation in peripheral sensory neurons underlies the ionic basis of pain hypersensitivity in response to vinca alkaloids

Boiko, N., Medrano, G., Montano, E., Jiang, N., Williams, C. R., Madungwe, N. B., Bopassa, J. C., Kim, C. C., Parrish, J. Z., Hargreaves, K. M., Stockand, J. D. & Eaton, B. A., Oct 2017, In : PloS one. 12, 10, e0186888.

Research output: Contribution to journalArticle

9 Scopus citations
2016

Alkaline activation of ClC-K2 chloride channels switches renal cells from reabsorbing to secreting

Wingo, C. S. & Stockand, J. D., 2016, In : Journal of General Physiology. 148, 3, p. 195-199 5 p.

Research output: Contribution to journalComment/debate

2 Scopus citations

Renal tubular epithelial cell prorenin receptor regulates blood pressure and sodium transport

Ramkumar, N., Stuart, D., Mironova, E., Bugay, V., Wang, S., Abraham, N., Ichihara, A., Stockand, J. D. & Kohan, D. E., Jul 1 2016, In : American Journal of Physiology - Renal Physiology. 311, 1, p. F186-F194

Research output: Contribution to journalArticle

21 Scopus citations
2015

Activation of ENaC by AVP contributes to the urinary concentrating mechanism and dilution of plasma

Mironova, E., Chen, Y., Pao, A. C., Roos, K. P., Kohan, D. E., Bugaj, V. & Stockand, J. D., Jan 1 2015, In : American Journal of Physiology - Renal Physiology. 308, 3, p. F237-F243

Research output: Contribution to journalArticle

14 Scopus citations

Coordination and fine motor control depend on Drosophila TRPγ

Akitake, B., Ren, Q., Boiko, N., Ni, J., Sokabe, T., Stockand, J. D., Eaton, B. A. & Montell, C., Jun 1 2015, In : Nature Communications. 6, 7288.

Research output: Contribution to journalArticle

10 Scopus citations

NOS1-dependent negative feedback regulation of the epithelial sodium channel in the collecting duct

Hyndman, K. A., Bugaj, V., Mironova, E., Stockand, J. D. & Pollock, J. S., Jan 1 2015, In : American Journal of Physiology - Renal Physiology. 308, 3, p. F244-F251

Research output: Contribution to journalArticle

21 Scopus citations
4 Scopus citations
16 Scopus citations

Salt and water loss in the distal colon

Berman, J. M. & Stockand, J. D., Dec 15 2015, In : Journal of Physiology. 593, 24, p. 5229 1 p.

Research output: Contribution to journalComment/debate

2014

Lack of an effect of collecting duct-specific deletion of adenylyl cyclase 3 on renal Na+ and water excretion or arterial pressure

Kittikulsuth, W., Stuart, D., Van Hoek, A. N., Stockand, J. D., Bugaj, V., Mironova, E., Blount, M. A. & Kohan, D. E., Mar 15 2014, In : American Journal of Physiology - Renal Physiology. 306, 6, p. F597-F607

Research output: Contribution to journalArticle

16 Scopus citations

Restrictive expression of acid-sensing ion channel 5 (Asic5) in unipolar brush cells of the vestibulocerebellum

Boiko, N., Kucher, V., Wang, B. & Stockand, J. D., Mar 24 2014, In : PloS one. 9, 3, e91326.

Research output: Contribution to journalArticle

17 Scopus citations
2013

Adenylyl cyclase VI mediates vasopressin-stimulated ENaC activity

Roos, K. P., Bugaj, V., Mironova, E., Stockand, J. D., Ramkumar, N., Rees, S. & Kohan, D. E., Jan 31 2013, In : Journal of the American Society of Nephrology. 24, 2, p. 218-227 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Inhibition of neuronal degenerin/epithelial Na+ channels by the multiple sclerosis drug 4-aminopyridine

Boiko, N., Kucher, V., Eaton, B. A. & Stockand, J. D., Mar 29 2013, In : Journal of Biological Chemistry. 288, 13, p. 9418-9427 10 p.

Research output: Contribution to journalArticle

24 Scopus citations

Patch-clamping drosophila sensory neurons

Kucher, V., Eaton, B. A., Stockand, J. D. & Boiko, N., May 8 2013, Ion Channels: Methods and Protocols. Gamper, N. (ed.). p. 385-397 13 p. (Methods in Molecular Biology; vol. 998).

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Recording ion channels in isolated, split-opened tubules

Mironova, E., Bugay, V., Pochynyuk, O., Staruschenko, A. & Stockand, J. D., May 8 2013, Ion Channels: Methods and Protocols. Gamper, N. (ed.). p. 341-353 13 p. (Methods in Molecular Biology; vol. 998).

Research output: Chapter in Book/Report/Conference proceedingChapter

8 Scopus citations

Renal Ion Channels, Electrophysiology of Transport, and Channelopathies

Stockand, J. D., Aug 29 2013, Seldin and Geibisch's The Kidney. Elsevier Inc., Vol. 1. p. 217-262 46 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

The inhibitory effect of Gβγ and Gβ isoform specificity on ENaC activity

Yu, L., Al-Khalili, O., Duke, B. J., Stockand, J. D., Eaton, D. C. & Bao, H. F., Nov 1 2013, In : American Journal of Physiology - Renal Physiology. 305, 9, p. F1365-F1373

Research output: Contribution to journalArticle

2 Scopus citations
2012
39 Scopus citations

Collecting duct-specific endothelin b receptor knockout increases enac activity

Bugaj, V., Mironova, E., Kohan, D. E. & Stockand, J. D., Jan 1 2012, In : American Journal of Physiology - Cell Physiology. 302, 1, p. C188-C194

Research output: Contribution to journalArticle

41 Scopus citations

Flow-sensitive K+-coupled ATP secretion modulates activity of the epithelial Na+ channel in the distal nephron

Bugaj, V., Sansom, S. C., Wen, D., Hatcher, L. I., Stockand, J. D. & Mironova, E., Nov 9 2012, In : Journal of Biological Chemistry. 287, 46, p. 38552-38558 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
25 Scopus citations

In vivo and ex vivo analysis of tubule function

Stockand, J. D., Vallon, V. & Ortiz, P., Dec 1 2012, In : Comprehensive Physiology. 2, 4, p. 2495-2525 31 p.

Research output: Contribution to journalArticle

7 Scopus citations

P2Y receptors and kidney function

Vallon, V., Stockand, J. & Rieg, T., Nov 1 2012, In : Wiley Interdisciplinary Reviews: Membrane Transport and Signaling. 1, 6, p. 731-742 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Pickpocket1 is an ionotropic molecular sensory transducer

Boiko, N., Kucher, V., Stockand, J. D. & Eaton, B. A., Nov 16 2012, In : Journal of Biological Chemistry. 287, 47, p. 39878-39886 9 p.

Research output: Contribution to journalArticle

Open Access
10 Scopus citations

The role of the epithelial Na + channel (enac) in high AVP but low aldosterone states

Stockand, J. D., Sep 25 2012, In : Frontiers in Physiology. 3 JUL, Article 304.

Research output: Contribution to journalShort survey

8 Scopus citations
2011

Acute cholesterol-induced anti-natriuretic effects: Role of epithelial Na+ channel activity, protein levels, and processing

Awayda, M. S., Awayda, K. L., Pochynyuk, O., Bugaj, V., Stockand, J. D. & Ortiz, R. M., Jan 21 2011, In : Journal of Biological Chemistry. 286, 3, p. 1683-1695 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

Diminished paracrine regulation of the epithelial Na+ channel by purinergic signaling in mice lacking connexin 30

Mironova, E., Peti-Peterdi, J., Bugaj, V. & Stockand, J. D., Jan 14 2011, In : Journal of Biological Chemistry. 286, 2, p. 1054-1060 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Role of collecting duct AT1a receptors in concentrating urine

Pochynyuk, O. & Stockand, J. D., Dec 1 2011, In : Journal of the American Society of Nephrology. 22, 12, p. 2144-2145 2 p.

Research output: Contribution to journalEditorial

Voltage-dependent gating underlies loss of ENaC function in pseudohypoaldosteronism type 1

Kucher, V., Boiko, N., Pochynyuk, O. & Stockand, J. D., Apr 20 2011, In : Biophysical Journal. 100, 8, p. 1930-1939 10 p.

Research output: Contribution to journalArticle

12 Scopus citations
2010

Dietary Na+ inhibits the open probability of the epithelial sodium channel in the kidney by enhancing apical P2Y2-receptor tone

Pochynyuk, O., Rieg, T., Bugaj, V., Schroth, J., Fridman, A., Boss, G. R., Insel, P. A., Stockand, J. D. & Vallon, V., Jun 1 2010, In : FASEB Journal. 24, 6, p. 2056-2065 10 p.

Research output: Contribution to journalArticle

73 Scopus citations

Purinergic inhibition of ENaC produces aldosterone escape

Stockand, J. D., Mironova, E., Bugaj, V., Rieg, T., Insel, P. A., Vallon, V., Peti-Peterdi, J. & Pochynyuk, O., Nov 1 2010, In : Journal of the American Society of Nephrology. 21, 11, p. 1903-1911 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

Vasopressin regulation of renal sodium excretion

Stockand, J. D., Nov 2010, In : Kidney international. 78, 9, p. 849-856 8 p.

Research output: Contribution to journalReview article

51 Scopus citations
2009

Activation of the epithelial Na+ channel in the collecting duct by vasopressin contributes to water reabsorption

Bugaj, V., Pochynyuk, O. & Stockand, J. D., Nov 1 2009, In : American Journal of Physiology - Renal Physiology. 297, 5, p. F1411-F1418

Research output: Contribution to journalArticle

60 Scopus citations

Intrinsic voltage dependence of the epithelial Na+ channel is masked by a conserved transmembrane domain tryptophan

Pochynyuk, O., Kucher, V., Boiko, N., Mironova, E., Staruschenko, A., Karpushev, A. V., Tong, Q., Hendron, E. & Stockand, J., Sep 18 2009, In : Journal of Biological Chemistry. 284, 38, p. 25512-25521 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Muscarinic M1 modulation of acid-sensing ion channels

Dorofeeva, N. A., Karpushev, A. V., Nikolaev, M. V., Bolshakov, K. V., Stockand, J. D. & Staruschenko, A., Oct 1 2009, In : NeuroReport. 20, 15, p. 1386-1391 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Thiazolidinedione-induced fluid retention is independent of collecting duct αENaC activity

Vallon, V., Hummler, E., Rieg, T., Pochynyuk, O., Bugaj, V., Schroth, J., Dechenes, G., Rossier, B., Cunard, R. & Stockand, J., Apr 1 2009, In : Journal of the American Society of Nephrology. 20, 4, p. 721-729 9 p.

Research output: Contribution to journalArticle

61 Scopus citations
2008

Insight toward epithelial Na+ channel mechanism revealed by the acid-sensing ion channel 1 structure

Stockand, J. D., Staruschenko, A., Pochynyuk, O., Booth, R. E. & Silverthorn, D. U., Dec 1 2008, In : IUBMB Life. 60, 9, p. 620-628 9 p.

Research output: Contribution to journalReview article

78 Scopus citations

Paracrine regulation of the epithelial Na+ channel in the mammalian collecting duct by purinergic P2Y2 receptor tone

Pochynyuk, O., Bugaj, V., Rieg, T., Insel, P. A., Mironova, E., Vallon, V. & Stockand, J. D., Dec 26 2008, In : Journal of Biological Chemistry. 283, 52, p. 36599-36607 9 p.

Research output: Contribution to journalArticle

101 Scopus citations

Physiologic regulation of the epithelial sodium channel by phosphatidylinositides

Pochynyuk, O., Bugaj, V. & Stockand, J. D., Sep 1 2008, In : Current Opinion in Nephrology and Hypertension. 17, 5, p. 533-540 8 p.

Research output: Contribution to journalReview article

50 Scopus citations

Purinergic control of apical plasma membrane PI(4,5)P2 levels sets ENaC activity in principal cells

Pochynyuk, O., Bugaj, V., Vandewalle, A. & Stockand, J. D., Jan 1 2008, In : American Journal of Physiology - Renal Physiology. 294, 1, p. F38-F46

Research output: Contribution to journalArticle

58 Scopus citations