James D Lechleiter

  • 5361 Citations
  • 34 h-Index
1984 …2020
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Fingerprint Dive into the research topics where James D Lechleiter is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 1 Similar Profiles
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Calcium Medicine & Life Sciences

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Projects 1985 2020

education
health science
pedagogics
science
trainee
Astrocytes
Emergency Responders
Pharmaceutical Preparations
Therapeutic Human Experimentation
Therapeutics

Research Output 1984 2019

  • 5361 Citations
  • 34 h-Index
  • 70 Article
  • 1 Chapter
  • 1 Conference contribution
  • 1 Review article

Prevention of brain damage after traumatic brain injury by pharmacological enhancement of KCNQ (Kv7, “M-type”) K+ currents in neurons

Vigil, F. A., Bozdemir, E., Bugay, V., Chun, S. H., Hobbs, M. A., Sanchez, I., Hastings, S. D., Veraza, R. J., Holstein, D. M., Sprague, S. M., M Carver, C., Cavazos, J. E., Brenner, R., Lechleiter, J. D. & Shapiro, M. S., Jan 1 2019, In : Journal of Cerebral Blood Flow and Metabolism.

Research output: Contribution to journalArticle

Pharmacology
Neurons
Brain
Physiological Stress
Seizures

Time to Target Stroke: Examining the Circadian System in Stroke

Stubblefield, J. J. & Lechleiter, J. D., Jun 1 2019, In : The Yale journal of biology and medicine. 92, 2, p. 349-357 9 p.

Research output: Contribution to journalReview article

Stroke
Blood
Astrocytes
Neurons
Clocks
10 Citations (Scopus)

Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer’s disease and vascular cognitive impairment

Van Skike, C. E., Jahrling, J. B., Olson, A. B., Sayre, N. L., Hussong, S. A., Ungvari, Z., Lechleiter, J. D. & Galvan Hart, V., Apr 1 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 314, 4, p. H693-H703

Research output: Contribution to journalArticle

Sirolimus
Blood-Brain Barrier
Blood Vessels
Alzheimer Disease
LDL Receptors

The long-term effect of maternal dietary protein restriction on 5-HT1A receptor function and behavioral responses to stress in adulthood

Ye, W., Pitlock, M. D., Javors, M. A., Thompson, B. J., Lechleiter, J. D. & Hensler, J. G., Jan 1 2018, (Accepted/In press) In : Behavioural Brain Research.

Research output: Contribution to journalArticle

Protein-Restricted Diet
Receptor, Serotonin, 5-HT1A
Dietary Proteins
Mothers
Psychiatry
4 Citations (Scopus)

Cyclophilin D over-expression increases mitochondrial complex III activity and accelerates supercomplex formation

Etzler, J. C., Bollo, M., Holstein, D., Deng, J. J., Perez, V., Lin, D. T., Richardson, A., Bai, Y. & Lechleiter, J. D., Jan 1 2017, In : Archives of Biochemistry and Biophysics. 613, p. 61-68 8 p.

Research output: Contribution to journalArticle

Electron Transport Complex III
Mitochondria
HEK293 Cells
Mitochondrial Proteins
Cells