James D Lechleiter

  • 5268 Citations
  • 34 h-Index
1984 …2020
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Projects 1985 2020

health science


Hinck, A. P., Sarantopoulos, J., Curiel, T. J., Lafer, E. M., Weintraub, S. E., Karnad, A. B., Lechleiter, J. D., Thompson, I. M., Leach, R. J., Christy, B. A., Allred, C., Johnson, K., Padmanabhan, S., I-Tien, Y., Naylor, S., Gazitt, Y., Pollock, B. H., Mundy, G., Bonewald, L., Davis, S., Lee, E., Oishi, N., Hasty, E., Vijg, J. N. M. N., Herman, B. A., Johnson, K., Moyer, M., Windle, J., McGill, J., O'Connell, P., Clark, G., Kuhn, J., Wolf, R., Allred, D. C., Weiss, G., Boldt, D., Coltman, C. & Huang, H.

National Institutes of Health


Project: Research project

Hispanic Americans
Financial Management

Research Output 1984 2018

  • 5268 Citations
  • 34 h-Index
  • 69 Article
  • 1 Chapter
  • 1 Conference contribution
6 Citations (Scopus)

Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer’s disease and vascular cognitive impairment

Van Skike, C. E., Jahrling, J. B., Olson, A. B., Sayre, N. L., Hussong, S. A., Ungvari, Z., Lechleiter, J. D. & Galvan Hart, V., Apr 1 2018, In : American Journal of Physiology - Heart and Circulatory Physiology. 314, 4, p. H693-H703

Research output: Contribution to journalArticle

Blood-Brain Barrier
Blood Vessels
Alzheimer Disease
LDL Receptors

The long-term effect of maternal dietary protein restriction on 5-HT1A receptor function and behavioral responses to stress in adulthood

Ye, W., Pitlock, M. D., Javors, M. A., Thompson, B. J., Lechleiter, J. D. & Hensler, J. G., Jan 1 2018, (Accepted/In press) In : Behavioural Brain Research.

Research output: Contribution to journalArticle

Protein-Restricted Diet
Receptor, Serotonin, 5-HT1A
Dietary Proteins
4 Citations (Scopus)

Cyclophilin D over-expression increases mitochondrial complex III activity and accelerates supercomplex formation

Etzler, J. C., Bollo, M., Holstein, D., Deng, J. J., Perez, V., Lin, D. T., Richardson, A., Bai, Y. & Lechleiter, J. D., Jan 1 2017, In : Archives of Biochemistry and Biophysics. 613, p. 61-68 8 p.

Research output: Contribution to journalArticle

Electron Transport Complex III
HEK293 Cells
Mitochondrial Proteins

Thyroid Hormone Stimulation of Adult Brain Fatty Acid Oxidation

Sifuentes, M. M. & Lechleiter, J. D., 2017, (Accepted/In press) In : Vitamins and Hormones.

Research output: Contribution to journalArticle

Thyroid Hormones
Fatty Acids
Brain Injuries
6 Citations (Scopus)

Calcineurin β protects brain after injury by activating the unfolded protein response

Chen, Y., Holstein, D. M., Aime, S., Bollo, M. & Lechleiter, J. D., Oct 1 2016, In : Neurobiology of Disease. 94, p. 139-156 18 p.

Research output: Contribution to journalArticle

Unfolded Protein Response
Brain Injuries
Sarcoplasmic Reticulum Calcium-Transporting ATPases


Drug for concussion, stroke found by UT scientist moves closer...

James D Lechleiter


2 items of media coverage

Press/Media: Press / Media

To Curb Brain Damage, Astrocyte Pharmaceuticals Energizes Cells

James D Lechleiter


1 item of media coverage

Press/Media: Press / Media

From the lab to the university classroom

Linda M Mcmanus & James D Lechleiter


1 item of media coverage

Press/Media: Press / Media