• 4997 Citations
  • 31 h-Index
1989 …2017

Research output per year

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Research Output

  • 4997 Citations
  • 31 h-Index
  • 40 Article
  • 1 Review article
2017

Autologous stem cell transplantation: The predictive value of the morse fall scale in hospitalized patients

Dee, V., Toro, J., Lee, S., Sherwood, P. & Haile, D., Oct 2017, In : Clinical Journal of Oncology Nursing. 21, 5, p. 599-604 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2016

Edentulism and transplant-associated complications in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplantation

Toro, J. J., Gushiken, F. C., Schneider, D., Lee, S., Haile, D. J. & Freytes, C. O., Aug 1 2016, In : Supportive Care in Cancer. 24, 8, p. 3411-3415 5 p.

Research output: Contribution to journalArticle

2012

Hematopoietic progenitor cell transplantation toxicities in multiple myeloma patients with bisphosphonate-induced osteonecrosis of the jaw: A longitudinal cohort study

Varadarajan, P., Toro, J. J., Lee, S., Schneider, D., Neumon, B., Frye, B., Craig, R. M., Haile, D. J. & Freytes, C. O., Nov 1 2012, In : Supportive Care in Cancer. 20, 11, p. 2969-2975 7 p.

Research output: Contribution to journalArticle

3 Scopus citations
2011

Heterogenous distribution of ferroportin-containing neurons in mouse brain

Boserup, M. W., Lichota, J., Haile, D. & Moos, T., Apr 1 2011, In : BioMetals. 24, 2, p. 357-375 19 p.

Research output: Contribution to journalArticle

31 Scopus citations
2010

Deficiency in the divalent metal transporter 1 increases bleomycin-induced lung injury

Yang, F., Stonehuerner, J. G., Richards, J. H., Nguyen, N. B., Callaghan, K. D., Haile, D. J. & Ghio, A. J., Aug 1 2010, In : BioMetals. 23, 4, p. 657-667 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
2009
2007

Lack of Haptoglobin Affects Iron Transport Across Duodenum by Modulating Ferroportin Expression

Marro, S., Barisani, D., Chiabrando, D., Fagoonee, S., Muckenthaler, M. U., Stolte, J., Meneveri, R., Haile, D., Silengo, L., Altruda, F. & Tolosano, E., Oct 2007, In : Gastroenterology. 133, 4, p. 1261-1271.e3

Research output: Contribution to journalArticle

23 Scopus citations

The dentate nucleus in Friedreich's ataxia: The role of iron-responsive proteins

Koeppen, A. H., Michael, S. C., Knutson, M. D., Haile, D. J., Qian, J., Levi, S., Santambrogio, P., Garrick, M. D. & Lamarche, J. B., Aug 1 2007, In : Acta Neuropathologica. 114, 2, p. 163-173 11 p.

Research output: Contribution to journalArticle

Open Access
90 Scopus citations
2006

Hepcidin expression and iron transport in alveolar macrophages

Nguyen, N. B., Callaghan, K. D., Ghio, A. J., Haile, D. J. & Yang, F., Sep 13 2006, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 291, 3, p. L417-L425

Research output: Contribution to journalArticle

94 Scopus citations
2005

Apical location of ferroportin 1 in airway epithelia and its role in iron detoxification in the lung

Yang, F., Haile, D. J., Wang, X., Dailey, L. A., Stonehuerner, J. G. & Ghio, A. J., Jul 1 2005, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 289, 1 33-1, p. L14-L23

Research output: Contribution to journalArticle

33 Scopus citations

Functional consequences of ferroportin 1 mutations

Liu, X. B., Yang, F. & Haile, D. J., Jul 1 2005, In : Blood Cells, Molecules, and Diseases. 35, 1, p. 33-46 14 p.

Research output: Contribution to journalArticle

103 Scopus citations

Regulation of hepcidin and ferroportin expression by lipopolysaccharide in splenic macrophages

Liu, X. B., Nguyen, N. B. H., Marquess, K. D., Yang, F. & Haile, D. J., Jul 1 2005, In : Blood Cells, Molecules, and Diseases. 35, 1, p. 47-56 10 p.

Research output: Contribution to journalArticle

102 Scopus citations
2004

Age Associated Alterations in Costimulatory and Adhesion Molecule Expression in Lupus-Prone Mice Are Attenuated by Food Restriction with n-6 and n-3 Fatty Acids

Muthukumar, A., Sun, D., Zaman, K., Barnes, J. L., Haile, D. & Fernandes, G., Sep 1 2004, In : Journal of Clinical Immunology. 24, 5, p. 471-480 10 p.

Research output: Contribution to journalArticle

14 Scopus citations

Copper-induced ferroportin-1 expression in J774 macrophages is associated with iron efflux

Chung, J., Haile, D. J. & Wessling-Resnick, M., Mar 2 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 9, p. 2700-2705 6 p.

Research output: Contribution to journalArticle

Open Access
48 Scopus citations
2003

Haptoglobin reduces lung injury associated with exposure to blood

Yang, F., Haile, D. J., Berger, F. G., Herbert, D. C., Van Beveren, E. & Ghio, A. J., Feb 1 2003, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 284, 2 28-2, p. L402-L409

Research output: Contribution to journalArticle

60 Scopus citations

Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages

Knutson, M. D., Vafa, M. R., Haile, D. J. & Wessling-Resnick, M., Dec 1 2003, In : Blood. 102, 12, p. 4191-4197 7 p.

Research output: Contribution to journalArticle

Open Access
169 Scopus citations

The role of the iron responsive element in the control of ferroportin1/IREG1/MTP1 gene expression

Lymboussaki, A., Pignatti, E., Montosi, G., Garuti, C., Haile, D. J. & Pietrangelo, A., Nov 2003, In : Journal of Hepatology. 39, 5, p. 710-715 6 p.

Research output: Contribution to journalArticle

119 Scopus citations
2002

Iron increases expression of iron-export protein MTP1 in lung cells

Yang, F., Wang, X., Haile, D. J., Piantadosi, C. A. & Ghio, A. J., Nov 1 2002, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 283, 5 27-5, p. L932-L939

Research output: Contribution to journalArticle

72 Scopus citations

Regulation of reticuloendothelial iron transporter MTP1 (Slc11a3) by inflammation

Yang, F., Liu, X. B., Quinones, M., Melby, P. C., Ghio, A. & Haile, D. J., Oct 18 2002, In : Journal of Biological Chemistry. 277, 42, p. 39786-39791 6 p.

Research output: Contribution to journalArticle

175 Scopus citations

Role of the ferroportin iron-responsive element in iron and nitric oxide dependent gene regulation

Liu, X. B., Hill, P. & Haile, D. J., Jan 1 2002, In : Blood cells, molecules & diseases. 29, 3, p. 315-326 12 p.

Research output: Contribution to journalArticle

75 Scopus citations
2001

Distribution of Divalent Metal Transporter 1 and Metal Transport Protein 1 in the normal and Belgrade rat

Burdo, J. R., Menzies, S. L., Simpson, I. A., Garrick, L. M., Garrick, M. D., Dolan, K. G., Haile, D. J., Beard, J. L. & Connor, J. R., Dec 15 2001, In : Journal of Neuroscience Research. 66, 6, p. 1198-1207 10 p.

Research output: Contribution to journalArticle

228 Scopus citations

Expression of the duodenal iron transporters divalent-metal transporter 1 and ferroportin 1 in iron deficiency and iron overload

Zoller, H., Koch, R. O., Theurl, I., Obrist, P., Pietrangelo, A., Montosi, G., Haile, D. J., Vogel, W. & Weiss, G., Jan 1 2001, In : Gastroenterology. 120, 6, p. 1412-1419 8 p.

Research output: Contribution to journalArticle

239 Scopus citations

Haptoglobin in lung defense

Yang, F., Haile, D. J., Coalson, J. J. & Ghio, A. J., Dec 1 2001, In : Redox Report. 6, 6, p. 372-374 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Osteoclast-stimulating Factor Interacts with the Spinal Muscular Atrophy Gene Product to Stimulate Osteoclast Formation

Kurihara, N., Menaa, C., Maeda, H., Haile, D. J. & Reddy, S. V., Nov 2 2001, In : Journal of Biological Chemistry. 276, 44, p. 41035-41039 5 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations
2000

A novel mammalian iron-regulated protein involved in intracellular iron metabolism

Abboud, S. & Haile, D. J., Jun 30 2000, In : Journal of Biological Chemistry. 275, 26, p. 19906-19912 7 p.

Research output: Contribution to journalArticle

947 Scopus citations
7 Scopus citations
1999

Regulation of genes of iron metabolism by the iron-response proteins

Haile, D. J., Oct 1999, In : American Journal of the Medical Sciences. 318, 4, p. 230-240 11 p.

Research output: Contribution to journalArticle

58 Scopus citations
1997

Homeostatic regulation of copper uptake in yeast via direct binding of MAC1 protein to upstream regulatory sequences of FRE1 and CTR1

Yamaguchi-Iwai, Y., Serpe, M., Haile, D., Yang, W., Kosman, D. J., Klausner, R. D. & Dancis, A., Aug 5 1997, In : Journal of Biological Chemistry. 272, 28, p. 17711-17718 8 p.

Research output: Contribution to journalArticle

Open Access
141 Scopus citations
1994

Molecular characterization of a copper transport protein in S. cerevisiae: An unexpected role for copper in iron transport

Dancis, A., Yuan, D. S., Haile, D., Askwith, C., Eide, D., Moehle, C., Kaplan, J. & Klausner, R. D., Jan 28 1994, In : Cell. 76, 2, p. 393-402 10 p.

Research output: Contribution to journalArticle

522 Scopus citations

The Saccharomyces cerevisiae copper transport protein (Ctr1p). Biochemical characterization, regulation by copper, and physiologic role in copper uptake

Dancis, A., Haile, D., Yuan, D. S. & Klausner, R. D., Jan 1 1994, In : Journal of Biological Chemistry. 269, 41, p. 25660-25667 8 p.

Research output: Contribution to journalArticle

328 Scopus citations
1993

Modification of a free Fe-S cluster cysteine residue in the active iron- responsive element-binding protein prevents RNA binding

Philpott, C. C., Haile, D., Rouault, T. A. & Klausner, R. D., Jan 1 1993, In : Journal of Biological Chemistry. 268, 24, p. 17655-17658 4 p.

Research output: Contribution to journalArticle

81 Scopus citations

The interaction between the iron-responsive element binding protein and its cognate rna is highly dependent upon both RNA sequence and structure

Jaffrey, S. R., Haile, D. J., Klausner, R. D. & Harford, J. B., Sep 25 1993, In : Nucleic acids research. 21, 19, p. 4627-4631 5 p.

Research output: Contribution to journalArticle

88 Scopus citations
1992

An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein

Rouault, T. A., Haile, D. J., Downey, W. E., Philpott, C. C., Tang, C., Samaniego, F., Chin, J., Paul, I., Orloff, D., Harford, J. B. & Klausner, R. D., Sep 1 1992, In : BioMetals. 5, 3, p. 131-140 10 p.

Research output: Contribution to journalReview article

71 Scopus citations

Cellular regulation of the iron-responsive element binding protein: Disassembly of the cubane iron-sulfur cluster results in high-affinity RNA binding

Haile, D. J., Rouault, T. A., Harford, J. B., Kennedy, M. C., Blondin, G. A., Beinert, H. & Klausner, R. D., Dec 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 24, p. 11735-11739 5 p.

Research output: Contribution to journalArticle

Open Access
253 Scopus citations

Reciprocal control of RNA-binding and aconitase activity in the regulation of the iron-responsive element binding protein: Role of the iron-sulfur cluster

Haile, D. J., Rouault, T. A., Tang, C. K., Chin, J., Harford, J. B. & Klausner, R. D., 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 16, p. 7536-7540 5 p.

Research output: Contribution to journalArticle

Open Access
205 Scopus citations
1991

A regulated RNA binding protein also possesses aconitase activity

Kaptain, S., Downey, W. E., Tang, C., Philpott, C., Haile, D., Orloff, D. G., Harford, J. B., Rouault, T. A. & Klausner, R. D., Jan 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 22, p. 10109-10113 5 p.

Research output: Contribution to journalArticle

Open Access
153 Scopus citations
1990

Cloning of the cDNA encoding an RNA regulatory protein-the human iron-responsive element-binding protein

Rouault, T. A., Tang, C. K., Kaptain, S., Burgess, W. H., Haile, D. J., Samaniego, F., McBride, O. W., Harford, J. B. & Klausner, R. D., Jan 1 1990, In : Proceedings of the National Academy of Sciences of the United States of America. 87, 20, p. 7958-7962 5 p.

Research output: Contribution to journalArticle

Open Access
142 Scopus citations

Specific high-affinity binding of host cell proteins to the 3' region of rubella virus RNA

Nakhasi, H. L., Rouault, T. A., Haile, D. J., Liu, T. Y. & Klausner, R. D., Jun 29 1990, In : New Biologist. 2, 3, p. 255-264 10 p.

Research output: Contribution to journalArticle

35 Scopus citations

The inhibition of the iron responsive element RNA-protein interaction by heme does not mimic in vivo iron regulation

Haile, D. J., Rouault, T. A., Harford, J. B. & Klausner, R. D., Aug 20 1990, In : Journal of Biological Chemistry. 265, 22, p. 12786-12789 4 p.

Research output: Contribution to journalArticle

38 Scopus citations
1989

Regulation of interaction of the iron-responsive element binding protein with iron-responsive RNA elements

Haile, D. J., Hentze, M. W., Rouault, T. A., Harford, J. B. & Klausner, R. D., 1989, In : Molecular and cellular biology. 9, 11 (5055-50619

Research output: Contribution to journalArticle

Open Access
118 Scopus citations

The iron-responsive element binding protein: A method for the affinity purification of a regulatory RNA-binding protein

Rouault, T. A., Hentze, M. W., Haile, D. J., Harford, J. B. & Klausner, R. D., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 15, p. 5768-5772 5 p.

Research output: Contribution to journalArticle

Open Access
87 Scopus citations