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Collaborations and top research areas from the last five years
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Antibody-Mediated Targeting of Secretory Protein SCUBE3 Suppresses Cancer Progression by Inhibiting Oncogenic Signaling and Inducing Antitumor Immunity
Singh, D., Onyeagucha, B. C., Medina, D., Subbarayalu, P., Mojidra, R., Lyu, D., Bhandari, M., Timilsina, S., Pitta Venkata, P., Huang, J. Y., Nirzhor, S., Abdulsahib, S., Prochnau, J. Y., Do, C. T. P., Rajamanickam, S., Chen, Y., Taylor, A. B., Viswanadhapalli, S., Falzone, M. & Jiang, J. X. & 5 others, , Mar 2 2026, In: Cancer Research. 86, 5, p. 1252-1268 17 p.Research output: Contribution to journal › Article › peer-review
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Correction to: Structural insights into BCDX2 complex function in homologous recombination (Nature, (2023), 619, 7970, (640-649), 10.1038/s41586-023-06219-w)
Rawal, Y., Jia, L., Meir, A., Zhou, S., Kaur, H., Ruben, E. A., Kwon, Y., Bernstein, K. A., Jasin, M., Taylor, A. B., Burma, S., Hromas, R., Mazin, A. V., Zhao, W., Zhou, D., Wasmuth, E. V., Greene, E. C., Sung, P. & Olsen, S. K., Jan 22 2026, In: Nature. 649, 8098, p. E12Research output: Contribution to journal › Comment/debate › peer-review
Open Access -
NF2 loss malignantly transforms human pancreatic acinar cells and enhances cell fitness under environmental stress
Xu, Y., Nipper, M. H., Dominguez, A. A., He, C., Sharkey, F. E., Khan, S., Xu, H., Zhou, D., Zheng, L., Luan, Y., Liu, J. & Wang, P., Jan 2 2026, In: The Journal of clinical investigation. 136, 1Research output: Contribution to journal › Article › peer-review
Open Access -
A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice
Yang, Y., Jn-Simon, N., He, Y., Sun, C., Zhang, P., Hu, W., Tian, T., Zeng, H., Basha, S., Huerta, A. S., Sun, L. Z., Yin, X. M., Hromas, R., Zheng, G., Pi, L. & Zhou, D., Mar 2025, In: Nature Aging. 5, 3, p. 386-400 15 p., 15691.Research output: Contribution to journal › Article › peer-review
Open Access27 Link opens in a new tab Scopus citations -
A novel regimen for pancreatic ductal adenocarcinoma targeting MEK, BCL-xL, and EGFR
Han, S., Tushoski-Alemán, G. W., Zhang, P., Zheng, G., Zhou, D., Huo, Z., Licht, J., George, T. J., Allegra, C., Trevino, J. G. & Hughes, S. J., Jan 2025, In: Neoplasia (United States). 59, 101070.Research output: Contribution to journal › Article › peer-review
Open Access5 Link opens in a new tab Scopus citations
Datasets
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Additional file 2 of Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12726547.v1, https://springernature.figshare.com/articles/dataset/Additional_file_2_of_Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/12726547/1
Dataset
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Additional file 3 of Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.12726550, https://springernature.figshare.com/articles/dataset/Additional_file_3_of_Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/12726550
Dataset
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Cryo-EM structure of a human BCDX2/ssDNA complex
Rawal, Y. (Contributor), Jia, L. (Contributor), Meir, A. (Contributor), Zhou, S. (Contributor), Kaur, H. (Contributor), Ruben, E. A. (Contributor), Kwon, Y. (Contributor), Bernstein, K. A. (Contributor), Jasin, M. (Contributor), Taylor, A. B. (Contributor), Burma, S. (Contributor), Hromas, R. (Contributor), Mazin, A. V. (Contributor), Zhao, W. (Contributor), Zhou, D. (Contributor), Wasmuth, E. V. (Contributor), Greene, E. C. (Contributor), Sung, P. (Contributor) & Olsen, S. K. (Contributor), Protein Data Bank (PDB), Jun 21 2023
DOI: 10.2210/pdb8GBJ/pdb, https://www.wwpdb.org/pdb?id=pdb_00008gbj
Dataset
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Cryo-EM structure of the human BCDX2 complex
Rawal, Y. (Contributor), Jia, L. (Contributor), Meir, A. (Contributor), Zhou, S. (Contributor), Kaur, H. (Contributor), Ruben, E. A. (Contributor), Kwon, Y. (Contributor), Bernstein, K. A. (Contributor), Jasin, M. (Contributor), Taylor, A. B. (Contributor), Burma, S. (Contributor), Hromas, R. (Contributor), Mazin, A. V. (Contributor), Zhao, W. (Contributor), Zhou, D. (Contributor), Wasmuth, E. V. (Contributor), Greene, E. C. (Contributor), Sung, P. (Contributor) & Olsen, S. K. (Contributor), Protein Data Bank (PDB), Jun 21 2023
DOI: 10.2210/pdb8FAZ/pdb, https://www.wwpdb.org/pdb?id=pdb_00008faz
Dataset
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Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies
He, Y. (Creator), Khan, S. (Creator), Huo, Z. (Creator), Lv, D. (Creator), Zhang, X. (Creator), Liu, X. (Creator), Yuan, Y. (Creator), Hromas, R. (Creator), Xu, M. (Creator), Zheng, G. (Creator) & Zhou, D. (Creator), Figshare, 2020
DOI: 10.6084/m9.figshare.c.5075029, https://springernature.figshare.com/collections/Proteolysis_targeting_chimeras_PROTACs_are_emerging_therapeutics_for_hematologic_malignancies/5075029
Dataset