Claudia L Satizabal Barrera

2020

Circulating ceramide ratios and risk of vascular brain aging and dementia

McGrath, E. R., Himali, J. J., Xanthakis, V., Duncan, M. S., Schaffer, J. E., Ory, D. S., Peterson, L. R., DeCarli, C., Pase, M. P., Satizabal, C. L., Vasan, R. S., Beiser, A. S. & Seshadri, S., Feb 1 2020, In: Annals of Clinical and Translational Neurology. 7, 2, p. 160-168 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

28 Scopus citations

Common genetic variation indicates separate causes for periventricular and deep white matter hyperintensities

Armstrong, N. J., Mather, K. A., Sargurupremraj, M., Knol, M. J., Malik, R., Satizabal, C. L., Yanek, L. R., Wen, W., Gudnason, V. G., Dueker, N. D., Elliott, L. T., Hofer, E., Bis, J., Jahanshad, N., Li, S., Logue, M. A., Luciano, M., Scholz, M., Smith, A. V. & Trompet, S. & 66 others, Vojinovic, D., Xia, R., Alfaro-Almagro, F., Ames, D., Amin, N., Amouyel, P., Beiser, A. S., Brodaty, H., Deary, I. J., Fennema-Notestine, C., Gampawar, P. G., Gottesman, R., Griffanti, L., Jack, C. R., Jenkinson, M., Jiang, J., Kral, B. G., Kwok, J. B., Lampe, L., Liewald, D. C. M., Maillard, P., Marchini, J., Bastin, M. E., Mazoyer, B., Pirpamer, L., Romero, J. R., Roshchupkin, G. V., Schofield, P. R., Schroeter, M. L., Stott, D. J., Thalamuthu, A., Trollor, J., Tzourio, C., van der Grond, J., Vernooij, M. W., Witte, V. A., Wright, M. J., Yang, Q., Morris, Z., Siggurdsson, S., Psaty, B., Villringer, A., Schmidt, H., Haberg, A. K., van Duijn, C. M., Wouter Jukema, J., Dichgans, M., Sacco, R. L., Wright, C. B., Kremen, W. S., Becker, L. C., Thompson, P. M., Mosley, T. H., Wardlaw, J. M., Ikram, M. A., Adams, H. H. H., Seshadri, S., Sachdev, P. S., Smith, S. M., Launer, L., Longstreth, W., DeCarli, C., Schmidt, R., Fornage, M., Debette, S. & Nyquist, P. A., Jul 2020, In: Stroke. 51, 7, p. 2112-2121 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

73 Scopus citations

Corticosteroids and Regional Variations in Thickness of the Human Cerebral Cortex across the Lifespan

Parker, N., Vidal-Pineiro, D., French, L., Shin, J., Adams, H. H. H., Brodaty, H., Cox, S. R., Deary, I. J., Fjell, A. M., Frenzel, S., Grabe, H., Hosten, N., Ikram, M. A., Jiang, J., Knol, M. J., Mazoyer, B., Mishra, A., Sachdev, P. S., Salum, G. & Satizabal, C. L. & 12 others, Schmidt, H., Schmidt, R., Seshadri, S., Schumann, G., Völzke, H., Walhovd, K. B., Wen, W., Wittfeld, K., Yang, Q., Debette, S., Pausova, Z. & Paus, T., Mar 21 2020, In: Cerebral Cortex. 30, 2, p. 575-586 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

11 Scopus citations

Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults

Hofer, E., Roshchupkin, G. V., Adams, H. H. H., Knol, M. J., Lin, H., Li, S., Zare, H., Ahmad, S., Armstrong, N. J., Satizabal, C. L., Bernard, M., Bis, J. C., Gillespie, N. A., Luciano, M., Mishra, A., Scholz, M., Teumer, A., Xia, R., Jian, X. & Mosley, T. H. & 363 others, Saba, Y., Pirpamer, L., Seiler, S., Becker, J. T., Carmichael, O., Rotter, J. I., Psaty, B. M., Lopez, O. L., Amin, N., van der Lee, S. J., Yang, Q., Himali, J. J., Maillard, P., Beiser, A. S., Decarli, C., Karama, S., Lewis, L., Harris, M., Bastin, M. E., Deary, I. J., Witte, A. V., Beyer, F., Loeffler, M., Mather, K. A., Schofield, P. R., Thalamuthu, A., Kwok, J. B., Wright, M. J., Ames, D., Trollor, J., Jiang, J., Brodaty, H., Wen, W., Vernooij, M. W., Hofman, A., Uitterlinden, A. G., Niessen, W. J., Wittfeld, K., Bülow, R., Völker, U., Pausova, Z., Pike, G. B., Maingault, S., Crivello, F., Tzourio, C., Amouyel, P., Mazoyer, B., Neale, M. C., Franz, C. E., Lyons, M. J., Panizzon, M. S., Andreassen, O. A., Dale, A. M., Logue, M., Grasby, K. L., Jahanshad, N., Painter, J. N., Colodro-Conde, L., Bralten, J., Hibar, D. P., Lind, P. A., Pizzagalli, F., Stein, J. L., Thompson, P. M., Medland, S. E., Sachdev, P. S., Kremen, W. S., Wardlaw, J. M., Villringer, A., van Duijn, C. M., Grabe, H. J., Longstreth, W. T., Fornage, M., Paus, T., Debette, S., Ikram, M. A., Schmidt, H., Schmidt, R., Seshadri, S., Ching, C. R. K., McMahon, M. A. B., Shatokhina, N., Zsembik, L. C. P., Agartz, I., Alhusaini, S., Almeida, M. A. A., Alnæs, D., Amlien, I. K., Andersson, M., Ard, T., Ashley-Koch, A., Brouwer, R. M., Buimer, E. E. L., Bürger, C., Cannon, D. M., Chakravarty, M., Chen, Q., Cheung, J. W., Couvy-Duchesne, B., Dalvie, S., de Araujo, T. K., de Zubicaray, G. I., de Zwarte, S. M. C., Braber, A. D., Doan, N. T., Dohm, K., Ehrlich, S., Engelbrecht, H. R., Erk, S., Fan, C. C., Fedko, I. O., Foley, S. F., Ford, J. M., Fukunaga, M., Garrett, M. E., Ge, T., Giddaluru, S., Goldman, A. L., Groenewold, N. A., Grotegerd, D., Gurholt, T. P., Gutman, B. A., Hansell, N. K., Harris, M. A., Harrison, M. B., Haswell, C. C., Hauser, M., Herms, S., Heslenfeld, D. J., Ho, N. F., Hoehn, D., Hoffmann, P., Holleran, L., Hoogman, M., Hottenga, J. J., Ikeda, M., Janowitz, D., Jansen, I. E., Jia, T., Jockwitz, C., Kanai, R., Kasperaviciute, D., Kaufmann, T., Kelly, S., Kikuchi, M., Klein, M., Knapp, M., Knodt, A. R., Krämer, B., Lam, M., Lancaster, T. M., Lee, P. H., Lett, T. A., Lopes-Cendes, I., Macciardi, F., Marquand, A. F., Mathias, S. R., Melzer, T. R., Milaneschi, Y., Mirza-Schreiber, N., Moreira, J. C. V., Mühleisen, T. W., Müller-Myhsok, B., Najt, P., Nakahara, S., Nho, K., Olde Loohuis, L. M., Orfanos, D. P., Pearson, J. F., Pitcher, T. L., Pütz, B., Ragothaman, A., Rashid, F. M., Redlich, R., Reinbold, C. S., Repple, J., Richard, G., Riedel, B. C., Risacher, S. L., Rocha, C. S., Mota, N. R., Salminen, L., Saremi, A., Saykin, A. J., Schlag, F., Schmaal, L., Secolin, R., Shapland, C. Y., Shen, L., Shin, J., Shumskaya, E., Sønderby, I. E., Sprooten, E., Strike, L. T., Tansey, K. E., Thomopoulos, S. I., Tordesillas-Gutiérrez, D., Turner, J. A., Uhlmann, A., Vallerga, C. L., Meer, D. V. D., van Donkelaar, M. M. J., Eijk, L. V., van Erp, T. G. M., van Haren, N. E. M., Rooij, D. V., Tol, M. J. V., Veldink, J. H., Verhoef, E., Walton, E., Wang, M., Wang, Y., Westlye, L. T., Whelan, C. D., Witt, S. H., Wolf, C., Wolfers, T., Yasuda, C. L., Zaremba, D., Zhang, Z., Zhu, A. H., Zwiers, M. P., Artiges, E., Assareh, A. A., Ayesa-Arriola, R., Belger, A., Brandt, C. L., Brown, G. G., Cichon, S., Curran, J. E., Davies, G. E., Degenhardt, F., Dietsche, B., Djurovic, S., Doherty, C. P., Espiritu, R., Garijo, D., Gil, Y., Gowland, P. A., Green, R. C., Häusler, A. N., Heindel, W., Ho, B. C., Hoffmann, W. U., Holsboer, F., Homuth, G., Hosten, N., Jack, C. R., Jang, M., Jansen, A., Kolskår, K., Koops, S., Krug, A., Lim, K. O., Luykx, J. J., Mathalon, D. H., Mattay, V. S., Matthews, S., Van Son, J. M., McEwen, S. C., Melle, I., Morris, D. W., Mueller, B. A., Nauck, M., Nordvik, J. E., Nöthen, M. M., O’leary, D. S., Opel, N., Martinot, M. L. P., Preda, A., Quinlan, E. B., Ratnakar, V., Reppermund, S., Steen, V. M., Torres, F. R., Veltman, D. J., Voyvodic, J. T., Whelan, R., White, T., Yamamori, H., Alvim, M. K. M., Anderson, T. J., Arias-Vasquez, A., Baune, B. T., Blangero, J. C., Boomsma, D. I., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bustillo, J. R., Cahn, W., Calhoun, V., Caseras, X., Caspers, S., Cavalleri, G. L., Cendes, F., Corvin, A., Crespo-Facorro, B., Dalrymple-Alford, J. C., Dannlowski, U., de Geus, E. J. C., Delanty, N., Depondt, C., Desrivières, S., Donohoe, G., Espeseth, T., Fernández, G., Fisher, S. E., Flor, H., Forstner, A. J., Francks, C., Franke, B., Glahn, D. C., Gollub, R. L., Gruber, O., Håberg, A. K., Hariri, A. R., Hartman, C. A., Hashimoto, R., Heinz, A., Hillegers, M. H. J., Hoekstra, P. J., Holmes, A. J., Hong, L. E., Hopkins, W. D., Hulshoff Pol, H. E., Jernigan, T. L., Jönsson, E. G., Kahn, R. S., Kennedy, M. A., Kircher, T. T. J., Kochunov, P., Le Hellard, S., Martin, N. G., Martinot, J. L., McDonald, C., McMahon, K. L., Meyer-Lindenberg, A., Morey, R. A., Nyberg, L., Oosterlaan, J., Ophoff, R. A., Penninx, B. W. J. H., Polderman, T. J. C., Posthuma, D., Rietschel, M., Roffman, J. L., Rowland, L. M., Sämann, P. G., Schumann, G., Sim, K., Sisodiya, S. M., Smoller, J. W., Sommer, I. E., Pourcain, B. S., Toga, A. W., Van der Wee, N. J. A., Van’T Ent, D., Völzke, H., Walter, H., Weber, B., Weinberger, D. R. & Zhou, J., Dec 1 2020, In: Nature communications. 11, 1, 4796.

Research output: Contribution to journal › Article › peer-review

Open Access

68 Scopus citations

Growth differentiation factor 15 and nt-probnp as blood-based markers of vascular brain injury and dementia

McGrath, E. R., Himali, J. J., Levy, D., Conner, S. C., Decarli, C., Pase, M. P., Ninomiya, T., Ohara, T., Courchesne, P., Satizabal, C. L., Vasan, R. S., Beiser, A. S. & Seshadri, S., Oct 6 2020, In: Journal of the American Heart Association. 9, 19, e014659.

Research output: Contribution to journal › Article › peer-review

Open Access

35 Scopus citations

Incident prolonged QT interval in midlife and late-life cognitive performance

Suemoto, C. K., Gibbons, L. E., Thacker, E. L., Jackson, J. D., Satizabal, C. L., Bettcher, B. M., Launer, L., Phillips, C., White, L. R. & Power, M. C., 2020, In: PloS one. 15, 2, e0229519.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

The genetic architecture of the human cerebral cortex

Enhancing NeuroImaging Genetics through Meta-Analysis Consortium (ENIGMA)-Genetics working group, Mar 20 2020, In: Science. 367, 6484, aay6690.

Research output: Contribution to journal › Article › peer-review

Open Access

512 Scopus citations

The genetics of circulating BDNF: Towards understanding the role of BDNF in brain structure and function in middle and old ages

Li, S., Weinstein, G., Zare, H., Teumer, A., Völker, U., Friedrich, N., Knol, M. J., Satizabal, C. L., Petyuk, V. A., Adams, H. H. H., Launer, L. J., Bennett, D. A., De Jager, P. L., Grabe, H. J., Ikram, M. A., Gudnason, V., Yang, Q. & Seshadri, S., 2020, In: Brain Communications. 2, 2, fcaa176.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Twenty-seven-year time trends in dementia incidence in Europe and the United States: The Alzheimer Cohorts Consortium

Wolters, F. J., Chibnik, L. B., Waziry, R., Anderson, R., Berr, C., Beiser, A., Bis, J. C., Blacker, D., Bos, D., Brayne, C., Dartigues, J. F., Darweesh, S. K. L., Davis-Plourde, K. L., De Wolf, F., Debette, S., Dufouil, C., Fornage, M., Goudsmit, J., Grasset, L. & Gudnason, V. & 23 others, Hadjichrysanthou, C., Helmer, C., Ikram, M. A., Ikram, M. K., Joas, E., Kern, S., Kuller, L. H., Launer, L., Lopez, O. L., Matthews, F. E., McRae-Mckee, K., Meirelles, O., Mosley, T. H., Pase, M. P., Psaty, B. M., Satizabal, C. L., Seshadri, S., Skoog, I., Stephan, B. C. M., Wetterberg, H., Wong, M. M., Zettergren, A. & Hofman, A., Aug 4 2020, In: Neurology. 95, 5, p. E519-E531

Research output: Contribution to journal › Article › peer-review

Open Access

285 Scopus citations

2019

A genome-wide association study identifies genetic loci associated with specific lobar brain volumes

van der Lee, S. J., Knol, M. J., Chauhan, G., Satizabal, C. L., Smith, A. V., Hofer, E., Bis, J. C., Hibar, D. P., Hilal, S., van den Akker, E. B., Arfanakis, K., Bernard, M., Yanek, L. R., Amin, N., Crivello, F., Cheung, J. W., Harris, T. B., Saba, Y., Lopez, O. L. & Li, S. & 42 others, van der Grond, J., Yu, L., Paus, T., Roshchupkin, G. V., Amouyel, P., Jahanshad, N., Taylor, K. D., Yang, Q., Mathias, R. A., Boehringer, S., Mazoyer, B., Rice, K., Cheng, C. Y., Maillard, P., van Heemst, D., Wong, T. Y., Niessen, W. J., Beiser, A. S., Beekman, M., Zhao, W., Nyquist, P. A., Chen, C., Launer, L. J., Psaty, B. M., Ikram, M. K., Vernooij, M. W., Schmidt, H., Pausova, Z., Becker, D. M., De Jager, P. L., Thompson, P. M., van Duijn, C. M., Bennett, D. A., Slagboom, P. E., Schmidt, R., Longstreth, W. T., Ikram, M. A., Seshadri, S., Debette, S., Gudnason, V., Adams, H. H. H. & DeCarli, C., Dec 1 2019, In: Communications Biology. 2, 1, 285.

Research output: Contribution to journal › Article › peer-review

Open Access

21 Scopus citations

A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease

Alzheimer’s Disease Sequencing Project, Mar 2019, In: Alzheimer's and Dementia. 15, 3, p. 441-452 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Assessment of Plasma Total Tau Level as a Predictive Biomarker for Dementia and Related Endophenotypes

Pase, M. P., Beiser, A. S., Himali, J. J., Satizabal, C. L., Aparicio, H. J., Decarli, C., Chêne, G., Dufouil, C. & Seshadri, S., May 2019, In: JAMA Neurology. 76, 5, p. 598-606 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

149 Scopus citations

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function (Nature Communications, (2018), 9, 1, (2098), 10.1038/s41467-018-04362-x)

Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., DeRosse, P. & Djurovic, S. & 202 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., van der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S. C., Lill, C. M., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L. P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Dan Rujescu, R., Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., Dec 1 2019, In: Nature communications. 10, 1, 2068.

Research output: Contribution to journal › Comment/debate › peer-review

Open Access

8 Scopus citations

Circulating fibroblast growth factor 23 levels and incident dementia: The Framingham heart study

McGrath, E. R., Himali, J. J., Levy, D., Conner, S. C., Pase, M. P., Abraham, C. R., Courchesne, P., Satizabal, C. L., Vasan, R. S., Beiser, A. S. & Seshadri, S., Mar 2019, In: PloS one. 14, 3, e0213321.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Circulating IGFBP-2: a novel biomarker for incident dementia

McGrath, E. R., Himali, J. J., Levy, D., Conner, S. C., DeCarli, C. S., Pase, M. P., Courchesne, P., Satizabal, C. L., Vasan, R. S., Beiser, A. S. & Seshadri, S., Sep 1 2019, In: Annals of Clinical and Translational Neurology. 6, 9, p. 1659-1670 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

38 Scopus citations

Full exploitation of high dimensionality in brain imaging: The JPND working group statement and findings

Adams, H. H. H., Roshchupkin, G. V., DeCarli, C., Franke, B., Grabe, H. J., Habes, M., Jahanshad, N., Medland, S. E., Niessen, W., Satizabal, C. L., Schmidt, R., Seshadri, S., Teumer, A., Thompson, P. M., Vernooij, M. W., Wittfeld, K. & Ikram, M. A., Dec 2019, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 11, p. 286-290 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting

Stroke Genetics Network (SiGN), International Stroke Genetics Consortium (ISGC), METASTROKE, Alzheimer’s Disease Genetics Consortium (ADGC) & Neurology Working Group of the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, Jan 29 2019, In: Neurology. 92, 5, p. E486-E503

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Genetic architecture of subcortical brain structures in 38,851 individuals

Satizabal, C. L., Adams, H. H. H., Hibar, D. P., White, C. C., Knol, M. J., Stein, J. L., Scholz, M., Sargurupremraj, M., Jahanshad, N., Roshchupkin, G. V., Smith, A. V., Bis, J. C., Jian, X., Luciano, M., Hofer, E., Teumer, A., van der Lee, S. J., Yang, J., Yanek, L. R. & Lee, T. V. & 269 others, Li, S., Hu, Y., Koh, J. Y., Eicher, J. D., Desrivières, S., Arias-Vasquez, A., Chauhan, G., Athanasiu, L., Rentería, M. E., Kim, S., Hoehn, D., Armstrong, N. J., Chen, Q., Holmes, A. J., den Braber, A., Kloszewska, I., Andersson, M., Espeseth, T., Grimm, O., Abramovic, L., Alhusaini, S., Milaneschi, Y., Papmeyer, M., Axelsson, T., Ehrlich, S., Roiz-Santiañez, R., Kraemer, B., Håberg, A. K., Jones, H. J., Pike, G. B., Stein, D. J., Stevens, A., Bralten, J., Vernooij, M. W., Harris, T. B., Filippi, I., Witte, A. V., Guadalupe, T., Wittfeld, K., Mosley, T. H., Becker, J. T., Doan, N. T., Hagenaars, S. P., Saba, Y., Cuellar-Partida, G., Amin, N., Hilal, S., Nho, K., Mirza-Schreiber, N., Arfanakis, K., Becker, D. M., Ames, D., Goldman, A. L., Lee, P. H., Boomsma, D. I., Lovestone, S., Giddaluru, S., Le Hellard, S., Mattheisen, M., Bohlken, M. M., Kasperaviciute, D., Schmaal, L., Lawrie, S. M., Agartz, I., Walton, E., Tordesillas-Gutierrez, D., Davies, G. E., Shin, J., Ipser, J. C., Vinke, L. N., Hoogman, M., Jia, T., Burkhardt, R., Klein, M., Crivello, F., Janowitz, D., Carmichael, O., Haukvik, U. K., Aribisala, B. S., Schmidt, H., Strike, L. T., Cheng, C. Y., Risacher, S. L., Pütz, B., Fleischman, D. A., Assareh, A. A., Mattay, V. S., Buckner, R. L., Mecocci, P., Dale, A. M., Cichon, S., Boks, M. P., Matarin, M., Penninx, B. W. J. H., Calhoun, V. D., Chakravarty, M. M., Marquand, A. F., Macare, C., Kharabian Masouleh, S., Oosterlaan, J., Amouyel, P., Hegenscheid, K., Rotter, J. I., Schork, A. J., Liewald, D. C. M., de Zubicaray, G. I., Wong, T. Y., Shen, L., Sämann, P. G., Brodaty, H., Roffman, J. L., de Geus, E. J. C., Tsolaki, M., Erk, S., van Eijk, K. R., Cavalleri, G. L., van der Wee, N. J. A., McIntosh, A. M., Gollub, R. L., Bulayeva, K. B., Bernard, M., Richards, J. S., Himali, J. J., Loeffler, M., Rommelse, N., Hoffmann, W., Westlye, L. T., Valdés Hernández, M. C., Hansell, N. K., van Erp, T. G. M., Wolf, C., Kwok, J. B. J., Vellas, B., Heinz, A., Olde Loohuis, L. M., Delanty, N., Ho, B. C., Ching, C. R. K., Shumskaya, E., Singh, B., Hofman, A., van der Meer, D., Homuth, G., Psaty, B. M., Bastin, M. E., Montgomery, G. W., Foroud, T. M., Reppermund, S., Hottenga, J. J., Simmons, A., Meyer-Lindenberg, A., Cahn, W., Whelan, C. D., van Donkelaar, M. M. J., Yang, Q., Hosten, N., Green, R. C., Thalamuthu, A., Mohnke, S., Hulshoff Pol, H. E., Lin, H., Jack, C. R., Schofield, P. R., Mühleisen, T. W., Maillard, P., Potkin, S. G., Wen, W., Fletcher, E., Toga, A. W., Gruber, O., Huentelman, M., Davey Smith, G., Launer, L. J., Nyberg, L., Jönsson, E. G., Crespo-Facorro, B., Koen, N., Greve, D. N., Uitterlinden, A. G., Weinberger, D. R., Steen, V. M., Fedko, I. O., Groenewold, N. A., Niessen, W. J., Toro, R., Tzourio, C., Longstreth, W. T., Ikram, M. K., Smoller, J. W., van Tol, M. J., Sussmann, J. E., Paus, T., Lemaître, H., Schroeter, M. L., Mazoyer, B., Andreassen, O. A., Holsboer, F., Depondt, C., Veltman, D. J., Turner, J. A., Pausova, Z., Schumann, G., van Rooij, D., Djurovic, S., Deary, I. J., McMahon, K. L., Müller-Myhsok, B., Brouwer, R. M., Soininen, H., Pandolfo, M., Wassink, T. H., Cheung, J. W., Wolfers, T., Martinot, J. L., Zwiers, M. P., Nauck, M., Melle, I., Martin, N. G., Kanai, R., Westman, E., Kahn, R. S., Sisodiya, S. M., White, T., Saremi, A., van Bokhoven, H., Brunner, H. G., Völzke, H., Wright, M. J., van ‘t Ent, D., Nöthen, M. M., Ophoff, R. A., Buitelaar, J. K., Fernández, G., Sachdev, P. S., Rietschel, M., van Haren, N. E. M., Fisher, S. E., Beiser, A. S., Francks, C., Saykin, A. J., Mather, K. A., Romanczuk-Seiferth, N., Hartman, C. A., DeStefano, A. L., Heslenfeld, D. J., Weiner, M. W., Walter, H., Hoekstra, P. J., Nyquist, P. A., Franke, B., Bennett, D. A., Grabe, H. J., Johnson, A. D., Chen, C., van Duijn, C. M., Lopez, O. L., Fornage, M., Wardlaw, J. M., Schmidt, R., DeCarli, C., De Jager, P. L., Villringer, A., Debette, S., Gudnason, V., Medland, S. E., Shulman, J. M., Thompson, P. M., Seshadri, S. & Ikram, M. A., Nov 1 2019, In: Nature Genetics. 51, 11, p. 1624-1636 13 p.

Research output: Contribution to journal › Article › peer-review

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176 Scopus citations

Mid-life and late-life vascular risk factor burden and neuropathology in old age

Conner, S. C., Pase, M. P., Carneiro, H., Raman, M. R., McKee, A. C., Alvarez, V. E., Walker, J. M., Satizabal, C. L., Himali, J. J., Stein, T. D., Beiser, A. & Seshadri, S., Dec 1 2019, In: Annals of Clinical and Translational Neurology. 6, 12, p. 2403-2412 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Plasma total-tau as a biomarker of stroke risk in the community

Pase, M. P., Himali, J. J., Aparicio, H. J., Romero, J. R., Satizabal, C. L., Maillard, P., DeCarli, C., Beiser, A. S. & Seshadri, S., Sep 2019, In: Annals of neurology. 86, 3, p. 463-467 5 p.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Serum magnesium and calcium levels in relation to ischemic stroke: Mendelian randomization study

Larsson, S. C., Traylor, M., Burgess, S., Boncoraglio, G. B., Jern, C., Michaëlsson, K., Markus, H. S., Malik, R., Chauhan, G., Sargurupremraj, M., Okada, Y., Mishra, A., Rutten-Jacobs, L., Giese, A. K., Van Der Laan, S. W., Gretarsdottir, S., Anderson, C. D., Chong, M., Adams, H. H. H. & Ago, T. & 237 others, Almgren, P., Amouyel, P., Ay, H., Bartz, R. M., Benavente, O. R., Bevan, S., Brown, R. D., Butterworth, A. S., Carrera, C., Carty, C. L., Chasman, D. I., Chen, W. M., Cole, J. W., Correa, A., Cotlarciuc, I., Cruchaga, C., Danesh, J., De Bakker, P. I. W., Destefano, A. L., Hoed, M. D., Duan, Q., Engelter, S. T., Falcone, G. J., Gottesman, R. F., Grewal, R. P., Gudnason, V., Gustafsson, S., Haessler, J., Harris, T. B., Hassan, A., Havulinna, A. S., Heckbert, S. R., Holliday, E. G., Howard, G., Hsu, F. C., Hyacinth, H. I., Ikram, M. A., Ingelsson, E., Irvin, M. R., Jian, X., Jiménez-Conde, J., Johnson, J. A., Jukema, J. W., Kanai, M., Keene, K. L., Kissela, B. M., Kleindorfer, D. O., Kooperberg, C., Kubo, M., Lange, L. A., Langefeld, C. D., Langenberg, C., Launer, L. J., Lee, J. M., Lemmens, R., Leys, D., Lewis, C. M., Lin, W. Y., Lindgren, A. G., Lorentzen, E., Magnusson, P. K., Maguire, J., Manichaikul, A., McArdle, P. F., Meschia, J. F., Mitchell, B. D., Mosley, T. H., Nalls, M. A., Ninomiya, T., O'Donnell, M. J., Psaty, B. M., Pulit, S. L., Rannikmäe, K., Reiner, A. P., Rexrode, K. M., Rice, K., Rich, S. S., Ridker, P. M., Rost, N. S., Rothwell, P. M., Rotter, J. I., Rundek, T., Sacco, R. L., Sakaue, S., Sale, M. M., Salomaa, V., Sapkota, B. R., Schmidt, R., Schmidt, C. O., Schminke, U., Sharma, P., Slowik, A., Sudlow, C. L. M., Tanislav, C., Tatlisumak, T., Taylor, K. D., Thijs, V. N. S., Thorleifsson, G., Thorsteinsdottir, U., Tiedt, S., Trompet, S., Tzourio, C., Van Duijn, C. M., Walters, M., Wareham, N. J., Wassertheil-Smoller, S., Wilson, J. G., Wiggins, K. L., Yang, Q., Yusuf, S., Amin, N., Aparicio, H. S., Arnett, D. K., Attia, J., Beiser, A. S., Berr, C., Buring, J. E., Bustamante, M., Caso, V., Cheng, Y. C., Choi, S. H., Chowhan, A., Cullell, N., Dartigues, J. F., Delavaran, H., Delgado, P., Dörr, M., Engström, G., Ford, I., Gurpreet, W. S., Hamsten, A., Heitsch, L., Hozawa, A., Ibanez, L., Ilinca, A., Ingelsson, M., Iwasaki, M., Jackson, R. D., Jood, K., Jousilahti, P., Kaffashian, S., Kalra, L., Kamouchi, M., Kitazono, T., Kjartansson, O., Kloss, M., Koudstaal, P. J., Krupinski, J., Labovitz, D. L., Laurie, C. C., Levi, C. R., Li, L., Lind, L., Lindgren, C. M., Lioutas, V., Liu, Y. M., Lopez, O. L., Makoto, H., Martinez-Majander, N., Matsuda, K., Minegishi, N., Montaner, J., Morris, A. P., Muiño, E., Müller-Nurasyid, M., Norrving, B., Ogishima, S., Parati, E. A., Peddareddygari, L. R., Pedersen, N. L., Pera, J., Perola, M., Pezzini, A., Pileggi, S., Rabionet, R., Riba-Llena, I., Ribasés, M., Romero, J. R., Roquer, J., Rudd, A. G., Sarin, A. P., Sarju, R., Sarnowski, C., Sasaki, M., Satizabal, C. L., Satoh, M., Sattar, N., Sawada, N., Sibolt, G., Sigurdsson, Á., Smith, A., Sobue, K., Soriano-Tárraga, C., Stanne, T., Stine, O. C., Stott, D. J., Strauch, K., Takai, T., Tanaka, H., Tanno, K., Teumer, A., Tomppo, L., Torres-Aguila, N. P., Touze, E., Tsugane, S., Uitterlinden, A. G., Valdimarsson, E. M., Van Der Lee, S. J., Völzke, H., Wakai, K., Weir, D., Williams, S. R., Wolfe, C. D. A., Wong, Q., Xu, H., Yamaji, T., Sanghera, D. K., Melander, O., Strbian, D., Fernandez-Cadenas, I., Longstreth, W. T., Rolfs, A., Hata, J., Woo, D., Rosand, J., Pare, G., Hopewell, J. C., Saleheen, D., Stefansson, K., Worrall, B. B., Kittner, S. J., Seshadri, S., Fornage, M., Howson, J. M. M., Kamatani, Y., Debette, S. & Dichgans, M., Feb 26 2019, In: Neurology. 92, 9, p. E944-E950

Research output: Contribution to journal › Article › peer-review

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48 Scopus citations

Temporal Trends in Ischemic Stroke Incidence in Younger Adults in the Framingham Study

Aparicio, H. J., Himali, J. J., Satizabal, C. L., Pase, M. P., Romero, J. R., Kase, C. S., Beiser, A. S. & Seshadri, S., 2019, In: Stroke. 50, 6, p. 1558-1560 3 p.

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Open Access

33 Scopus citations

2018

APOE and the association of fatty acids with the risk of stroke, coronary heart disease, and mortality

Satizabal, C. L., Samieri, C., Davis-Plourde, K. L., Voetsch, B., Aparicio, H. J., Pase, M. P., Romero, J. R., Helmer, C., Vasan, R. S., Kase, C. S., Debette, S., Beiser, A. S. & Seshadri, S., 2018, In: Stroke. 49, 12, p. 2822-2829 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

34 Scopus citations

Association of nonalcoholic fatty liver disease with lower brain volume in healthy middle-aged adults in the Framingham Study

Weinstein, G., Zelber-Sagi, S., Preis, S. R., Beiser, A. S., DeCarli, C., Speliotes, E. K., Satizabal, C. L., Vasan, R. S. & Seshadri, S., Jan 2018, In: JAMA Neurology. 75, 1, p. 97-104 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

133 Scopus citations

Author response: Sleep architecture and the risk of incident dementia in the community

Pase, M. P., Himali, J. J., Grima, N. A., Beiser, A. S., Satizabal, C. L., Aparicio, H. J., Thomas, R. J., Gottlieb, D. J., Auerbach, S. H. & Seshadri, S., 2018, In: Neurology. 90, 10, p. 487 1 p.

Research output: Contribution to journal › Comment/debate › peer-review

2 Scopus citations

Cerebral tract integrity relates to white matter hyperintensities, cortex volume, and cognition

Seiler, S., Fletcher, E., Hassan-Ali, K., Weinstein, M., Beiser, A., Himali, J. J., Satizabal, C. L., Seshadri, S., DeCarli, C. & Maillard, P., Dec 2018, In: Neurobiology of Aging. 72, p. 14-22 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

Circulating vascular growth factors and magnetic resonance imaging markers of small vessel disease and atrophy in middle-aged adults

Raman, M. R., Himali, J. J., Conner, S. C., DeCarli, C., Vasan, R. S., Beiser, A. S., Seshadri, S., Maillard, P. & Satizabal, C. L., 2018, In: Stroke. 49, 9, p. 2227-2229 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Exome chip analysis identifies low-frequency and rare variants in MRPL38 for white matter hyperintensities on brain magnetic resonance imaging

neuroCHARGE Working Group, 2018, In: Stroke. 49, 8, p. 1812-1819 8 p.

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Open Access

17 Scopus citations

Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

ARUK Consortium, GERAD/PERADES, CHARGE, ADGC, EADI, International Genomics of Alzheimer's Project (IGAP), ARUK Consortium & GERAD/PERADES, CHARGE, ADGC, EADI, Jan 1 2018, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 10, p. 595-598 4 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume

Vojinovic, D., Adams, H. H., Jian, X., Yang, Q., Smith, A. V., Bis, J. C., Teumer, A., Scholz, M., Armstrong, N. J., Hofer, E., Saba, Y., Luciano, M., Bernard, M., Trompet, S., Yang, J., Gillespie, N. A., van der Lee, S. J., Neumann, A., Ahmad, S. & Andreassen, O. A. & 71 others, Ames, D., Amin, N., Arfanakis, K., Bastin, M. E., Becker, D. M., Beiser, A. S., Beyer, F., Brodaty, H., Bryan, R. N., Bülow, R., Dale, A. M., De Jager, P. L., Deary, I. J., DeCarli, C., Fleischman, D. A., Gottesman, R. F., van der Grond, J., Gudnason, V., Harris, T. B., Homuth, G., Knopman, D. S., Kwok, J. B., Lewis, C. E., Li, S., Loeffler, M., Lopez, O. L., Maillard, P., El Marroun, H., Mather, K. A., Mosley, T. H., Muetzel, R. L., Nauck, M., Nyquist, P. A., Panizzon, M. S., Pausova, Z., Psaty, B. M., Rice, K., Rotter, J. I., Royle, N., Satizabal, C. L., Schmidt, R., Schofield, P. R., Schreiner, P. J., Sidney, S., Stott, D. J., Thalamuthu, A., Uitterlinden, A. G., Valdés Hernández, M. C., Vernooij, M. W., Wen, W., White, T., Witte, A. V., Wittfeld, K., Wright, M. J., Yanek, L. R., Tiemeier, H., Kremen, W. S., Bennett, D. A., Jukema, J. W., Paus, T., Wardlaw, J. M., Schmidt, H., Sachdev, P. S., Villringer, A., Grabe, H. J., Longstreth, W. T., van Duijn, C. M., Launer, L. J., Seshadri, S., Ikram, M. A. & Fornage, M., Dec 1 2018, In: Nature communications. 9, 1, 3945.

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Open Access

30 Scopus citations

Meta-analysis of epigenome-wide association studies of cognitive abilities

Marioni, R. E., McRae, A. F., Bressler, J., Colicino, E., Hannon, E., Li, S., Prada, D., Smith, J. A., Trevisi, L., Tsai, P. C., Vojinovic, D., Simino, J., Levy, D., Liu, C., Mendelson, M., Satizabal, C. L., Yang, Q., Jhun, M. A., Kardia, S. L. R. & Zhao, W. & 27 others, Bandinelli, S., Ferrucci, L., Hernandez, D. G., Singleton, A. B., Harris, S. E., Starr, J. M., Kiel, D. P., McLean, R. R., Just, A. C., Schwartz, J., Spiro, A., Vokonas, P., Amin, N., Ikram, M. A., Uitterlinden, A. G., van Meurs, J. B. J., Spector, T. D., Steves, C., Baccarelli, A. A., Bell, J. T., van Duijn, C. M., Fornage, M., Hsu, Y. H., Mill, J., Mosley, T. H., Seshadri, S. & Deary, I. J., Nov 1 2018, In: Molecular psychiatry. 23, 11, p. 2133-2144 12 p.

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62 Scopus citations

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

Neurology Working Group of the CHARGE Consortium, NINDS Stroke Genetics Network (SiGN), UK Young Lacunar DNA Study, MEGAST ROKE Consortium, AFGen Consortium, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium, International Genomics of Blood Pressure (iGEN-BP) Consortium, INVENT Consortium, STA RNET BioBank Japan Cooperative Hospital Group, COMPASS Consortium, EPIC-CVD Consortium, EPIC-InterAct Consortium, International Stroke Genetics Consortium (ISGC) & METAST ROKE Consortium, Apr 1 2018, In: Nature Genetics. 50, 4, p. 524-537 14 p.

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1121 Scopus citations

Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., Hagenaars, S. P., Ritchie, S. J., Marioni, R. E., Fawns-Ritchie, C., Liewald, D. C. M., Okely, J. A., Ahola-Olli, A. V., Barnes, C. L. K., Bertram, L., Bis, J. C., Burdick, K. E., Christoforou, A., Derosse, P. & Djurovic, S. & 201 others, Espeseth, T., Giakoumaki, S., Giddaluru, S., Gustavson, D. E., Hayward, C., Hofer, E., Ikram, M. A., Karlsson, R., Knowles, E., Lahti, J., Leber, M., Li, S., Mather, K. A., Melle, I., Morris, D., Oldmeadow, C., Palviainen, T., Payton, A., Pazoki, R., Petrovic, K., Reynolds, C. A., Sargurupremraj, M., Scholz, M., Smith, J. A., Smith, A. V., Terzikhan, N., Thalamuthu, A., Trompet, S., Van Der Lee, S. J., Ware, E. B., Windham, B. G., Wright, M. J., Yang, J., Yu, J., Ames, D., Amin, N., Amouyel, P., Andreassen, O. A., Armstrong, N. J., Assareh, A. A., Attia, J. R., Attix, D., Avramopoulos, D., Bennett, D. A., Böhmer, A. C., Boyle, P. A., Brodaty, H., Campbell, H., Cannon, T. D., Cirulli, E. T., Congdon, E., Conley, E. D., Corley, J., Cox, S. R., Dale, A. M., Dehghan, A., Dick, D., Dickinson, D., Eriksson, J. G., Evangelou, E., Faul, J. D., Ford, I., Freimer, N. A., Gao, H., Giegling, I., Gillespie, N. A., Gordon, S. D., Gottesman, R. F., Griswold, M. E., Gudnason, V., Harris, T. B., Hartmann, A. M., Hatzimanolis, A., Heiss, G., Holliday, E. G., Joshi, P. K., Kähönen, M., Kardia, S. L. R., Karlsson, I., Kleineidam, L., Knopman, D. S., Kochan, N. A., Konte, B., Kwok, J. B., Le Hellard, S., Lee, T., Lehtimäki, T., Li, S. C., Liu, T., Koini, M., London, E., Longstreth, W. T., Lopez, O. L., Loukola, A., Luck, T., Lundervold, A. J., Lundquist, A., Lyytikäinen, L. P., Martin, N. G., Montgomery, G. W., Murray, A. D., Need, A. C., Noordam, R., Nyberg, L., Ollier, W., Papenberg, G., Pattie, A., Polasek, O., Poldrack, R. A., Psaty, B. M., Reppermund, S., Riedel-Heller, S. G., Rose, R. J., Rotter, J. I., Roussos, P., Rovio, S. P., Saba, Y., Sabb, F. W., Sachdev, P. S., Satizabal, C. L., Schmid, M., Scott, R. J., Scult, M. A., Simino, J., Slagboom, P. E., Smyrnis, N., Soumaré, A., Stefanis, N. C., Stott, D. J., Straub, R. E., Sundet, K., Taylor, A. M., Taylor, K. D., Tzoulaki, I., Tzourio, C., Uitterlinden, A., Vitart, V., Voineskos, A. N., Kaprio, J., Wagner, M., Wagner, H., Weinhold, L., Wen, K. H., Widen, E., Yang, Q., Zhao, W., Adams, H. H. H., Arking, D. E., Bilder, R. M., Bitsios, P., Boerwinkle, E., Chiba-Falek, O., Corvin, A., De Jager, P. L., Debette, S., Donohoe, G., Elliott, P., Fitzpatrick, A. L., Gill, M., Glahn, D. C., Hägg, S., Hansell, N. K., Hariri, A. R., Ikram, M. K., Jukema, J. W., Vuoksimaa, E., Keller, M. C., Kremen, W. S., Launer, L., Lindenberger, U., Palotie, A., Pedersen, N. L., Pendleton, N., Porteous, D. J., Räikkönen, K., Raitakari, O. T., Ramirez, A., Reinvang, I., Rudan, I., Rujescu, D., Schmidt, R., Schmidt, H., Schofield, P. W., Schofield, P. R., Starr, J. M., Steen, V. M., Trollor, J. N., Turner, S. T., Van Duijn, C. M., Villringer, A., Weinberger, D. R., Weir, D. R., Wilson, J. F., Malhotra, A., McIntosh, A. M., Gale, C. R., Seshadri, S., Mosley, T. H., Bressler, J., Lencz, T. & Deary, I. J., Dec 1 2018, In: Nature communications. 9, 1, 2098.

Research output: Contribution to journal › Article › peer-review

Open Access

437 Scopus citations

Vascular risk at younger ages most strongly associates with current and future brain volume

Pase, M. P., Davis-Plourde, K., Himali, J. J., Satizabal, C. L., Aparicio, H., Seshadri, S., Beiser, A. S. & DeCarli, C., Oct 16 2018, In: Neurology. 91, 16, p. E1479-E1486

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Open Access

42 Scopus citations

Whole genome sequence analyses of brain imaging measures in the Framingham Study

NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, On behalf of the TOPMed Neurocognitive Working Group, Jan 2018, In: Neurology. 90, 3, p. E188-E196

Research output: Contribution to journal › Article › peer-review

Open Access

32 Scopus citations

2017

Aortic Stiffness, Increased White Matter Free Water, and Altered Microstructural Integrity: A Continuum of Injury

Maillard, P., Mitchell, G. F., Himali, J. J., Beiser, A., Fletcher, E., Tsao, C. W., Pase, M. P., Satizabal, C. L., Vasan, R. S., Seshadri, S. & DeCarli, C., Jun 1 2017, In: Stroke. 48, 6, p. 1567-1573 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

100 Scopus citations

Associations between social relationship measures, serum brain-derived neurotrophic factor, and risk of stroke and dementia

Salinas, J., Beiser, A., Himali, J. J., Satizabal, C. L., Aparicio, H. J., Weinstein, G., Mateen, F. J., Berkman, L. F., Rosand, J. & Seshadri, S., Jun 1 2017, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 3, 2, p. 229-237 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

67 Scopus citations

Clinical and environmental correlates of serum BDNF: A descriptive study with plausible implications for AD research

Weinstein, G., Preis, S. R., Beiser, A. S., Kaess, B., Chen, T. C., Satizabal, C., Rahman, F., Benjamin, E. J., Vasan, R. S. & Seshadri, S., 2017, In: Current Alzheimer Research. 14, 7, p. 722-730 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

Novel genetic loci associated with hippocampal volume

Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J. & Athanasiu, L. & 312 others, Axelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-Partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., MacAre, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., McKay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van Der Grond, J., Van Der Lee, S. J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., Decarli, C., Delanty, N., Depondt, C., Destefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, F. J., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Haren, N. E. M., Van 'T Ent, D., Van Tol, M. J., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., Jan 18 2017, In: Nature communications. 8, 13624.

Research output: Contribution to journal › Article › peer-review

Open Access

221 Scopus citations

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R., Van Der Lee, S. J., Naj, A. C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B. W., Boland, A., Raybould, R., Bis, J. C., Martin, E. R., Grenier-Boley, B., Heilmann-Heimbach, S., Chouraki, V., Kuzma, A. B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R. R. & Olaso, R. & 426 others, Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Longstreth, W. T., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J. C., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Decarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L. W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Fernadez, C. M., Benito, Y. A., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C. K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Uitterlinden, A. G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Goate, A. M., Pericak-Vance, M. A., Holmans, P. A., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D., Sep 1 2017, In: Nature Genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

682 Scopus citations

Role of Improved Vascular Health in the Declining Incidence of Dementia

Pase, M. P., Satizabal, C. L. & Seshadri, S., Jul 1 2017, In: Stroke. 48, 7, p. 2013-2020 8 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

36 Scopus citations

Sleep architecture and the risk of incident dementia in the community

Pase, M. P., Himali, J. J., Grima, N. A., Beiser, A. S., Satizabal, C. L., Aparicio, H. J., Thomas, R. J., Gottlieb, D. J., Auerbach, S. H. & Seshadri, S., Sep 19 2017, In: Neurology. 89, 12, p. 1244-1250 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

157 Scopus citations

Sugar- and Artificially Sweetened Beverages and the Risks of Incident Stroke and Dementia: A Prospective Cohort Study

Pase, M. P., Himali, J. J., Beiser, A. S., Aparicio, H. J., Satizabal, C. L., Vasan, R. S., Seshadri, S. & Jacques, P. F., May 1 2017, In: Stroke. 48, 5, p. 1139-1146 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

140 Scopus citations

Sugary beverage intake and preclinical Alzheimer's disease in the community

Pase, M. P., Himali, J. J., Jacques, P. F., DeCarli, C., Satizabal, C. L., Aparicio, H., Vasan, R. S., Beiser, A. S. & Seshadri, S., Sep 2017, In: Alzheimer's and Dementia. 13, 9, p. 955-964 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

37 Scopus citations

Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium

Chibnik, L. B., Wolters, F. J., Bäckman, K., Beiser, A., Berr, C., Bis, J. C., Boerwinkle, E., Bos, D., Brayne, C., Dartigues, J. F., Darweesh, S. K. L., Debette, S., Davis-Plourde, K. L., Dufouil, C., Fornage, M., Grasset, L., Gudnason, V., Hadjichrysanthou, C., Helmer, C. & Ikram, M. A. & 19 others, Ikram, M. K., Kern, S., Kuller, L. H., Launer, L., Lopez, O. L., Matthews, F., Meirelles, O., Mosley, T., Ower, A., Psaty, B. M., Satizabal, C. L., Seshadri, S., Skoog, I., Stephan, B. C. M., Tzourio, C., Waziry, R., Wong, M. M., Zettergren, A. & Hofman, A., Oct 1 2017, In: European Journal of Epidemiology. 32, 10, p. 931-938 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

25 Scopus citations

Whole blood gene expression and white matter Hyperintensities

Lin, H., Satizabal, C., Xie, Z., Yang, Q., Huan, T., Joehanes, R., Wen, C., Munson, P. J., Beiser, A., Levy, D. & Seshadri, S., Sep 18 2017, In: Molecular Neurodegeneration. 12, 1, 67.

Research output: Contribution to journal › Article › peer-review

Open Access

16 Scopus citations

2016

Aortic Stiffness and the Risk of Incident Mild Cognitive Impairment and Dementia

Pase, M. P., Beiser, A., Himali, J. J., Tsao, C., Satizabal, C. L., Vasan, R. S., Seshadri, S. & Mitchell, G. F., Sep 1 2016, In: Stroke. 47, 9, p. 2256-2261 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

117 Scopus citations

Association of Ideal Cardiovascular Health With Vascular Brain Injury and Incident Dementia

Pase, M. P., Beiser, A., Enserro, D., Xanthakis, V., Aparicio, H., Satizabal, C. L., Himali, J. J., Kase, C. S., Vasan, R. S., DeCarli, C. & Seshadri, S., May 1 2016, In: Stroke. 47, 5, p. 1201-1206 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

108 Scopus citations

Effects of arterial stiffness on brain integrity in young adults from the framingham heart study

Maillard, P., Mitchell, G. F., Himali, J. J., Beiser, A., Tsao, C. W., Pase, M. P., Satizabal, C. L., Vasan, R. S., Seshadri, S. & De Carli, C., 2016, In: Stroke. 47, 4, p. 1030-1036 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

89 Scopus citations

Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept

Psychosis Endophenotypes International Consortium, Feb 23 2016, In: Nature Neuroscience. 19, 3, p. 420-431 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

169 Scopus citations

Claudia L Satizabal Barrera

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