• 1453 Citations
  • 21 h-Index
19972020

Research output per year

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Research Output

  • 1453 Citations
  • 21 h-Index
  • 43 Article
  • 4 Chapter
  • 3 Review article
  • 1 Comment/debate
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Article
2020

The splicing component ISY1 regulates APE1 in base excision repair

Jaiswal, A. S., Williamson, E. A., Srinivasan, G., Kong, K., Lomelino, C. L., McKenna, R., Walter, C., Sung, P., Narayan, S. & Hromas, R., Feb 2020, In : DNA Repair. 86, 102769.

Research output: Contribution to journalArticle

Open Access
2019

ASR352, A potent anticancer agent: Synthesis, preliminary SAR, and biological activities against colorectal cancer bulk, 5-fluorouracil/oxaliplatin resistant and stem cells

Narayan, S., Ramisetti, S., Jaiswal, A. S., Law, B. K., Singh-Pillay, A., Singh, P., Amin, S. & Sharma, A. K., Jan 1 2019, In : European Journal of Medicinal Chemistry. 161, p. 456-467 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers

Srinivasan, G., Williamson, E. A., Kong, K., Jaiswal, A. S., Huang, G., Kim, H. S., Schärer, O., Zhao, W., Burma, S., Sung, P. & Hromas, R., Aug 27 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17438-17443 6 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2017

Endonuclease EEPD1 Is a gatekeeper for repair of stressed replication forks

Kim, H. S., Nickoloff, J. A., Wu, Y., Williamson, E. A., Sidhu, G. S., Reinert, B. L., Jaiswal, A. S., Srinivasan, G., Patel, B., Kong, K., Burma, S., Lee, S. H. & Hromas, R. A., Feb 17 2017, In : Journal of Biological Chemistry. 292, 7, p. 2795-2804 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

NSC30049 inhibits Chk1 pathway in 5-FU-resistant CRC bulk and stem cell populations

Narayan, S., Jaiswal, A. S., Sharma, R., Nawab, A., Duckworth, L. V., Law, B. K., Zajac-Kaye, M., George, T. J., Sharma, J., Sharma, A. K. & Hromas, R. A., Jan 1 2017, In : Oncotarget. 8, 34, p. 57246-57264 19 p.

Research output: Contribution to journalArticle

5 Scopus citations

Synthetic lethality in malignant pleural mesothelioma with PARP1 inhibition

Srinivasan, G., Sidhu, G. S., Williamson, E. A., Jaiswal, A. S., Najmunnisa, N., Wilcoxen, K., Jones, D., George, T. J. & Hromas, R., Oct 1 2017, In : Cancer chemotherapy and pharmacology. 80, 4, p. 861-867 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

The endonuclease EEPD1 mediates synthetic lethality in RAD52-depleted BRCA1 mutant breast cancer cells

Hromas, R., Kim, H. S., Sidhu, G., Williamson, E., Jaiswal, A., Totterdale, T. A., Nole, J., Lee, S. H., Nickoloff, J. A. & Kong, K. Y., Nov 16 2017, In : Breast Cancer Research. 19, 1, 122.

Research output: Contribution to journalArticle

9 Scopus citations
2016

The homologous recombination component EEPD1 is required for genome stability in response to developmental stress of vertebrate embryogenesis

Chun, C., Wu, Y., Lee, S. H., Williamson, E. A., Reinert, B. L., Jaiswal, A. S., Nickoloff, J. A. & Hromas, R. A., Apr 2 2016, In : Cell Cycle. 15, 7, p. 957-962 6 p.

Research output: Contribution to journalArticle

5 Scopus citations
2015

EEPD1 Rescues Stressed Replication Forks and Maintains Genome Stability by Promoting End Resection and Homologous Recombination Repair

Wu, Y., Lee, S. H., Williamson, E. A., Reinert, B. L., Cho, J. H., Xia, F., Jaiswal, A. S., Srinivasan, G., Patel, B., Brantley, A., Zhou, D., Shao, L., Pathak, R., Hauer-Jensen, M., Singh, S., Kong, K., Wu, X., Kim, H. S., Beissbarth, T., Gaedcke, J. & 3 others, Burma, S., Nickoloff, J. A. & Hromas, R. A., Jan 1 2015, In : PLoS Genetics. 11, 12, e1005675.

Research output: Contribution to journalArticle

25 Scopus citations

NSC666715 and Its analogs inhibit strand-displacement activity of DNA polymerase β and potentiate temozolomide-induced DNA damage, senescence and apoptosis in colorectal cancer cells

Jaiswal, A. S., Panda, H., Law, B. K., Sharma, J., Jani, J., Hromas, R. & Narayan, S., May 1 2015, In : PLoS One. 10, 5, e0123808.

Research output: Contribution to journalArticle

10 Scopus citations
2014

Anti-tumor activity of novel biisoquinoline derivatives against breast cancers

Jaiswal, A. S., Hirsch-Weil, D., Proulx, E. R., Hong, S. & Narayan, S., Oct 15 2014, In : Bioorganic and Medicinal Chemistry Letters. 24, 20, p. 4850-4853 4 p.

Research output: Contribution to journalArticle

3 Scopus citations
2013

Adenomatous polyposis coli- mediated accumulation of abasic dna lesions lead to cigarette smoke condensate- induced neoplastic transformation of normal breast epithelial cells

Jaiswal, A. S., Panda, H., Pampo, C. A., Siemann, D. W., Gary Gairola, C., Hromas, R. & Narayan, S., Apr 2013, In : Neoplasia (United States). 15, 4, p. 454-460 7 p.

Research output: Contribution to journalArticle

8 Scopus citations
2012

Adenomatous polyposis coli interacts with flap endonuclease 1 to block its nuclear entry and function

Jaiswal, A. S., Armas, M. L., Izumi, T., Strauss, P. R. & Narayan, S., Jun 2012, In : Neoplasia (United States). 14, 6, p. 495-508 14 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations
2011

Assembly of the base excision repair complex on abasic DNA and role of adenomatous polyposis coli on its functional activity

Jaiswal, A. S. & Narayan, S., Mar 22 2011, In : Biochemistry. 50, 11, p. 1901-1909 9 p.

Research output: Contribution to journalArticle

14 Scopus citations

DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer

Jaiswal, A. S., Banerjee, S., Aneja, R., Sarkar, F. H., Ostrov, D. A. & Narayan, S., 2011, In : PloS one. 6, 2, e16691.

Research output: Contribution to journalArticle

Open Access
33 Scopus citations
2009

9-Bromonoscapine-induced mitotic arrest of cigarette smoke condensate-transformed breast epithelial cells

Jaiswal, A. S., Aneja, R., Connors, S. K., Joshi, H. C., Multani, A. S., Pathak, S. & Narayan, S., Apr 15 2009, In : Journal of Cellular Biochemistry. 106, 6, p. 1146-1156 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Amino acid Asp181 of 5′-flap endonuclease 1 is a useful target for chemotherapeutic development

Panda, H., Jaiswal, A. S., Corsino, P. E., Armas, M. L., Law, B. K. & Narayan, S., Oct 27 2009, In : Biochemistry. 48, 42, p. 9952-9958 7 p.

Research output: Contribution to journalArticle

24 Scopus citations

A Novel inhibitor of DNA polymerase β enhances the ability of temozolomide to impair the growth of colon cancer cells

Jaiswal, A. S., Banerjee, S., Panda, H., Bulkin, C. D., Izumi, T., Sarkar, F. H., Ostrov, D. A. & Narayan, S., Dec 1 2009, In : Molecular Cancer Research. 7, 12, p. 1973-1983 11 p.

Research output: Contribution to journalArticle

Open Access
35 Scopus citations

C/EBPβ-mediated transcriptional regulation of bcl-xl gene expression in human breast epithelial cells in response to cigarette smoke condensate

Connors, S. K., Balusu, R., Kundu, C. N., Jaiswal, A. S., Gairola, C. G. & Narayan, S., Feb 12 2009, In : Oncogene. 28, 6, p. 921-932 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Genome based cell population heterogeneity promotes tumorigenicity: The evolutionary mechanism of cancer

Ye, C. J., Stevens, J. B., Liu, G., Bremer, S. W., Jaiswal, A. S., Ye, K. J., Lin, M. F., Lawrenson, L., Lancaster, W. D., Kurkinen, M., Liao, J. D., Gairola, C. G., Shekhar, M. P. V., Narayan, S., Miller, F. R. & Heng, H. H. Q., May 1 2009, In : Journal of Cellular Physiology. 219, 2, p. 288-300 13 p.

Research output: Contribution to journalArticle

68 Scopus citations
2008

A novel function of adenomatous polyposis coli (APC) in regulating DNA repair

Jaiswal, A. S. & Narayan, S., Nov 28 2008, In : Cancer Letters. 271, 2, p. 272-280 9 p.

Research output: Contribution to journalArticle

45 Scopus citations
2007

Adenomatous polyposis coli-mediated hypersensitivity of mouse embryonic fibroblast cell lines to methylmethane sulfonate treatment: Implication of base excision repair pathways

Kundu, C. N., Balusu, R., Jaiswal, A. S. & Narayan, S., Oct 1 2007, In : Carcinogenesis. 28, 10, p. 2089-2095 7 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations

Cigarette smoke condensate-induced level of adenomatous polyposis coli blocks long-patch base excision repair in breast epithelial cells

Kundu, C. N., Balusu, R., Jaiswal, A. S., Gairola, C. G. & Narayan, S., Mar 1 2007, In : Oncogene. 26, 10, p. 1428-1438 11 p.

Research output: Contribution to journalArticle

Open Access
38 Scopus citations

Structure/function analysis of the interaction of adenomatous polyposis coli with DNA polymerase β and its implications for base excision repair

Balusu, R., Jaiswal, A. S., Armas, M. L., Kundu, C. N., Bloom, L. B. & Narayan, S., Dec 11 2007, In : Biochemistry. 46, 49, p. 13961-13974 14 p.

Research output: Contribution to journalArticle

30 Scopus citations
2006
Open Access
23 Scopus citations

Mechanism of adenomatous polyposis coli (APC)-mediated blockage of long-patch base excision repair

Jaiswal, A. S., Balusu, R., Armas, M. L., Kundu, C. N. & Narayan, S., Dec 26 2006, In : Biochemistry. 45, 51, p. 15903-15914 12 p.

Research output: Contribution to journalArticle

36 Scopus citations
2005
Open Access
57 Scopus citations
2004

Cigarette smoke condensate-induced transformation of normal human breast epithelial cells in vitro

Narayan, S., Jaiswal, A. S., Kang, D., Srivastava, P., Das, G. M. & Gairola, C. G., Aug 5 2004, In : Oncogene. 23, 35, p. 5880-5889 10 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations
Open Access
19 Scopus citations
4 Scopus citations

Zinc stabilizes adenomatous polyposis coli (APC) protein levels and induces cell cycle arrest in colon cancer cells

Jaiswal, A. S. & Narayan, S., Dec 1 2004, In : Journal of Cellular Biochemistry. 93, 2, p. 345-357 13 p.

Research output: Contribution to journalArticle

40 Scopus citations
2002
Open Access
46 Scopus citations
21 Scopus citations

Telomere dynamics, aging, and cancer: Study of human syndromes characteristic of premature aging

Multani, A. S., Narayan, S., Jaiswal, A. S., Zhao, Y. J., Barkley, R. A., Furlong, C. L. & Pathak, S., Jan 1 2002, In : Journal of anti-aging medicine. 5, 3, p. 271-281 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

β-catenin-mediated transactivation and cell - cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells

Jaiswal, A. S., Marlow, B. P., Gupta, N. & Narayan, S., Dec 5 2002, In : Oncogene. 21, 55, p. 8414-8427 14 p.

Research output: Contribution to journalArticle

Open Access
313 Scopus citations
2001

DNA alkylation-induced phosphorylation of p53 and activation of kinases in colon cancer cells.

Jaiswal, A. S. & Narayan, S., Sep 2001, In : International journal of oncology. 19, 3, p. 613-616 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

DNA damage-induced cell cycle checkpoints involve both p53-dependent and -independent pathways: Role of telomere repeat binding factor 2

Narayan, S., Jaiswal, A. S., Multani, A. S. & Pathak, S., Sep 14 2001, In : British Journal of Cancer. 85, 6, p. 898-901 4 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

p53-dependent Transcriptional Regulation of the APC Promoter in Colon Cancer Cells Treated with DNA Alkylating Agents

Jaiswal, A. S. & Narayan, S., Jan 25 2001, In : Journal of Biological Chemistry. 276, 21, p. 18193-18199 7 p.

Research output: Contribution to journalArticle

Open Access
45 Scopus citations
49 Scopus citations
1999

A correlation of APC and c-myc mRNA levels in lung cancer cell lines.

Jaiswal, A. S., Kennedy, C. H. & Narayan, S., Jan 1 1999, In : Oncology reports. 6, 6, p. 1253-1256 4 p.

Research output: Contribution to journalArticle

10 Scopus citations
1 Scopus citations
1998
10 Scopus citations
1997
Open Access
62 Scopus citations