Andrew P Hinck

Hinck, A. P., Sarantopoulos, J., Curiel, T. J., Lafer, E. M., Weintraub, S. E., Karnad, A. B., Lechleiter, J. D., Thompson, I. M., Leach, R. J., Christy, B. A., Allred, C., Johnson, K., Padmanabhan, S., I-Tien, Y., Naylor, S., Gazitt, Y., Pollock, B. H., Mundy, G., Bonewald, L., Davis, S., Lee, E., Oishi, N., Hasty, E., Vijg, J. N. M. N., Herman, B. A., Johnson, K., Moyer, M., Windle, J., McGill, J., O'Connell, P., Clark, G., Kuhn, J., Wolf, R., Allred, D. C., Weiss, G., Boldt, D., Coltman, C. & Huang, H.

National Institutes of Health

9/1/91 → 7/31/19

Project: Research project

Research Output

2928 Citations
31 h-Index
72 Article
4 Letter
4 Review article
3 Comment/debate
5 More

Structural Adaptation in Its Orphan Domain Engenders Betaglycan with an Alternate Mode of Growth Factor Binding Relative to Endoglin

Kim, S. K., Whitley, M. J., Krzysiak, T. C., Hinck, C. S., Taylor, A. B., Zwieb, C., Byeon, C. H., Zhou, X., Mendoza, V., López-Casillas, F., Furey, W. & Hinck, A. P., Sep 3 2019, In : Structure. 27, 9, p. 1427-1442.e4

Research output: Contribution to journal › Article

Open Access

2 Scopus citations

Structural biology of betaglycan and endoglin, membrane-bound co-receptors of the TGF-beta family

Kim, S. K., Henen, M. A. & Hinck, A. P., Dec 1 2019, In : Experimental Biology and Medicine. 244, 17, p. 1547-1558 12 p.

Research output: Contribution to journal › Review article

4 Scopus citations

Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity

Goebel, E. J., Corpina, R. A., Hinck, C. S., Czepnik, M., Castonguay, R., Grenha, R., Boisvert, A., Miklossy, G., Fullerton, P. T., Matzuk, M. M., Idone, V. J., Economides, A. N., Kumar, R., Hinck, A. P. & Thompson, T. B., Jul 30 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 31, p. 15505-15513 9 p.

Research output: Contribution to journal › Article

Open Access

10 Scopus citations

TGF-2 uses the concave surface of its extended finger region to bind betaglycan’s ZP domain via three residues specific to TGF- and inhibin-

Henen, M. A., Mahlawat, P., Zwieb, C., Kodali, R. B., Hinck, C. S., Hanna, R. D., Krzysiak, T. C., Ilangovan, U., Cano, K. E., Hinck, G., Vonberg, M., McCabe, M. & Hinck, A. P., Mar 1 2019, In : Journal of Biological Chemistry. 294, 9, p. 3065-3080 16 p.

Research output: Contribution to journal › Article

4 Scopus citations

A novel TGFβ trap blocks chemotherapeutics-induced TGFβ1 signaling and enhances their anticancer activity in gynecologic cancers

Zhu, H., Gu, X., Xia, L., Zhou, Y., Bouamar, H., Yang, J., Ding, X., Zwieb, C., Zhang, J., Hinck, A. P., Sun, L. Z. & Zhu, X., Jun 15 2018, In : Clinical Cancer Research. 24, 12, p. 2780-2793 14 p.

Research output: Contribution to journal › Article