Alaa S Awad

  • 1423 Citations
  • 19 h-Index
20032020

Research output per year

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Research Output

  • 1423 Citations
  • 19 h-Index
  • 27 Article
  • 2 Review article
  • 1 Editorial
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Article
2020

Enhancing kidney DDAH-1 expression by adenovirus delivery reduces ADMA and ameliorates diabetic nephropathy

Wetzel, M. D., Gao, T., Stanley, K., Cooper, T. K., Morris, S. M. & Awad, A. S., Feb 2020, In : American Journal of Physiology - Renal Physiology. 312, 2, p. F509-F517

Research output: Contribution to journalArticle

1 Scopus citations
2019

l-Homoarginine supplementation prevents diabetic kidney damage

Wetzel, M. D., Gao, T., Venkatachalam, M., Morris, S. M. & Awad, A. S., Sep 1 2019, In : Physiological Reports. 7, 18, e14235.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations
2017

Arginase-2 mediates renal ischemia-reperfusion injury

Raup-Konsavage, W. M., Gao, T., Cooper, T. K., Morris, S. M., Reeves, W. B. & Awad, A. S., Aug 10 2017, In : American Journal of Physiology - Renal Physiology. 313, 2, p. F522-F534

Research output: Contribution to journalArticle

7 Scopus citations

Distinct roles of arginases 1 and 2 in diabetic nephropathy

Morris, S. M., You, H., Gao, T., Vacher, J., Cooper, T. K. & Awad, A. S., Oct 1 2017, In : American Journal of Physiology - Renal Physiology. 313, 4, p. F899-F905

Research output: Contribution to journalArticle

2 Scopus citations

Podocyte-specific chemokine (C-C motif) receptor 2 overexpression mediates diabetic renal injury in mice

You, H., Gao, T., Raup-Konsavage, W. M., Cooper, T. K., Bronson, S. K., Reeves, W. B. & Awad, A. S., Mar 1 2017, In : Kidney International. 91, 3, p. 671-682 12 p.

Research output: Contribution to journalArticle

13 Scopus citations
2015

Arginase inhibition: A new treatment for preventing progression of established diabetic nephropathy

You, H., Gao, T., Cooper, T. K., Morris, S. M. & Awad, A. S., Sep 4 2015, In : American Journal of Physiology - Renal Physiology. 309, 5, p. F447-F455

Research output: Contribution to journalArticle

15 Scopus citations

Delayed treatment with a small pigment epithelium derived factor (PEDF) peptide prevents the progression of diabetic renal injury

Awad, A. S., You, H., Gao, T., Gvritishvili, A., Cooper, T. K. & Tombran-Tink, J., Jul 24 2015, In : PloS one. 10, 7, e0133777.

Research output: Contribution to journalArticle

7 Scopus citations

Macrophage-derived tumor necrosis factor-α mediates diabetic renal injury

Awad, A. S., You, H., Gao, T., Cooper, T. K., Nedospasov, S. A., Vacher, J., Wilkinson, P. F., Farrell, F. X. & Brian Reeves, W., Oct 3 2015, In : Kidney international. 88, 4, p. 722-733 12 p.

Research output: Contribution to journalArticle

70 Scopus citations

Tissue Distribution, Excretion and Pharmacokinetics of the Environmental Pollutant Dibenzo[def,p]chrysene in Mice

Sun, Y. W., El-Bayoumy, K., Aliaga, C., Awad, A. S., Gowda, K., Amin, S. & Chen, K. M., Jul 20 2015, In : Chemical research in toxicology. 28, 7, p. 1427-1433 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
2014

Diabetic nephropathy is resistant to oral L-arginine or L-citrulline supplementation

You, H., Gao, T., Cooper, T. K., Morris, S. M. & Awad, A. S., Dec 1 2014, In : American Journal of Physiology - Renal Physiology. 307, 11, p. F1292-F1301

Research output: Contribution to journalArticle

19 Scopus citations
2013

Arginase inhibition mediates renal tissue protection in diabetic nephropathy by a nitric oxide synthase 3-dependent mechanism

You, H., Gao, T., Cooper, T. K., Morris, S. M. & Awad, A. S., Dec 2013, In : Kidney International. 84, 6, p. 1189-1197 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

Macrophages directly mediate diabetic renal injury

You, H., Gao, T., Cooper, T. K., Reeves, W. B. & Awad, A. S., Dec 15 2013, In : American Journal of Physiology - Renal Physiology. 305, 12, p. F1719-F1727

Research output: Contribution to journalArticle

65 Scopus citations

Protective role of small pigment epithelium-derived factor (PEDF) peptide in diabetic renal injury

Awad, A. S., Gao, T., Gvritishvili, A., You, H., Liu, Y., Cooper, T. K., Brian Reeves, W. & Tombran-Tink, J., Sep 15 2013, In : American Journal of Physiology - Renal Physiology. 305, 6, p. F891-F900

Research output: Contribution to journalArticle

16 Scopus citations
2011

Arginase-2 mediates diabetic renal injury

Morris, S. M., Gao, T., Cooper, T. K., Kepka-Lenhart, D. & Awad, A. S., Nov 2011, In : Diabetes. 60, 11, p. 3015-3022 8 p.

Research output: Contribution to journalArticle

50 Scopus citations

Chronic sphingosine 1-phosphate 1 receptor activation attenuates early-stage diabetic nephropathy independent of lymphocytes

Awad, A. S., Rouse, M. D., Khutsishvili, K., Huang, L., Bolton, W. K., Lynch, K. R. & Okusa, M. D., May 2011, In : Kidney international. 79, 10, p. 1090-1098 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

Monocyte/macrophage chemokine receptor CCR2 mediates diabetic renal injury

Awad, A. S., Kinsey, G. R., Khutsishvili, K., Gao, T., Bolton, W. K. & Okusa, M. D., Dec 2011, In : American Journal of Physiology - Renal Physiology. 301, 6, p. F1358-F1366

Research output: Contribution to journalArticle

64 Scopus citations
2009

Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury

Awad, A. S., Rouse, M., Huang, L., Vergis, A. L., Reutershan, J., Cathro, H. P., Linden, J. & Okusa, M. D., Apr 1 2009, In : Kidney international. 75, 7, p. 689-698 10 p.

Research output: Contribution to journalArticle

134 Scopus citations

Divergent roles of sphingosine kinases in kidney ischemia-reperfusion injury

Jo, S. K., Bajwa, A., Ye, H., Vergis, A. L., Awad, A. S., Kharel, Y., Lynch, K. R. & Okusa, M. D., Jan 1 2009, In : Kidney International. 75, 2, p. 167-175 9 p.

Research output: Contribution to journalArticle

57 Scopus citations
2008

Activation of adenosine 2A receptors preserves structure and function of podocytes

Awad, A. S., Rouse, M., Liu, L., Vergis, A. L., Rosin, D. L., Linden, J., Sedor, J. R. & Okusa, M. D., Jan 2008, In : Journal of the American Society of Nephrology. 19, 1, p. 59-68 10 p.

Research output: Contribution to journalArticle

33 Scopus citations
2007

Activation of adenosine 2A receptors attenuates allograft rejection and alloantigen recognition

Sevigny, C. P., Li, L., Awad, A. S., Huang, L., McDuffie, M., Linden, J., Lobo, P. I. & Okusa, M. D., Apr 1 2007, In : Journal of Immunology. 178, 7, p. 4240-4249 10 p.

Research output: Contribution to journalArticle

97 Scopus citations
78 Scopus citations
2006

Adenosine A2A receptor activation attenuates inflammation and injury in diabetic nephropathy

Awad, A. S., Huang, L., Ye, H., Duong, E. T. A., Bolton, W. K., Linden, J. & Okusa, M. D., Apr 2006, In : American Journal of Physiology - Renal Physiology. 290, 4, p. F828-F837

Research output: Contribution to journalArticle

106 Scopus citations

Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney

Awad, A. S., Ye, H., Huang, L., Li, L., Foss, F. W., Macdonald, T. L., Lynch, K. R. & Okusa, M. D., Jun 2006, In : American Journal of Physiology - Renal Physiology. 290, 6, p. F1516-F1524

Research output: Contribution to journalArticle

176 Scopus citations
2005

Increased renal production of angiotensin II and thromboxane B2 in conscious diabetic rats

Awad, A. S., Webb, R. L., Carey, R. M. & Siragy, H. M., Apr 2005, In : American Journal of Hypertension. 18, 4, p. 544-548 5 p.

Research output: Contribution to journalArticle

10 Scopus citations
2004

Renal nitric oxide production is decreased in diabetics rats and improved by AT1 receptor blockade

Awad, A. S., Webb, R. L., Carey, R. M. & Siragy, H. M., Aug 2004, In : Journal of Hypertension. 22, 8, p. 1571-1577 7 p.

Research output: Contribution to journalArticle

28 Scopus citations
2003

The angiotensin II type 1 receptor mediates renal interstitial content of tumor necrosis factor-α in diabetic rats

Siragy, H. M., Awad, A., Abadir, P. & Webb, R., Jun 1 2003, In : Endocrinology. 144, 6, p. 2229-2233 5 p.

Research output: Contribution to journalArticle

51 Scopus citations

Urinary and renal interstitial concentrations of TNF-α increase prior to the rise in albuminuria in diabetic rats

Kalantarinia, K., Awad, A. S. & Siragy, H. M., Oct 1 2003, In : Kidney International. 64, 4, p. 1208-1213 6 p.

Research output: Contribution to journalArticle

115 Scopus citations