Organization profile

Organization profile

Imagine living with strength and vitality throughout your life span, growing older with vigor and without disability. The Sam and Ann Barshop Institute for Longevity and Aging Studies brings together the world’s leading scientists in aging and longevity research, and providing them with the latest technologies in the application of cutting-edge research methods, supports their drive for excellence in scientific inquiry, an essential element to bringing good health and enhanced quality of life to our aging population.

Aging affects everyone. Never before in the history of humankind has understanding how and why we age been so important. As human life expectancy continues to increase, so must our scientific knowledge of aging processes to ensure healthy longevity, free of the disabilities brought about by age-related diseases and conditions.

The Barshop Institute supports research on age-related diseases and longevity. The Institute is designated as a Nathan Shock Center and the Claude D. Pepper Center and supports translational research with the goal of improving health throughout life. The Institute is also actively involved in community outreach programs to educate health care professionals on health issues facing the aging population.

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Fingerprint Dive into the research topics where Sam and Ann Barshop Institute for Longevity and Aging Studies is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.

pioglitazone Medicine & Life Sciences
Insulin Resistance Medicine & Life Sciences
Insulin Medicine & Life Sciences
Glucose Medicine & Life Sciences
Type 2 Diabetes Mellitus Medicine & Life Sciences
AMP-Activated Protein Kinases Medicine & Life Sciences
Glucose Intolerance Medicine & Life Sciences
Muscles Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 1979 2020

Callithrix
Research
Research Personnel
Pharmacology
Health

NATHAN SHOCK AGING CENTER

Musi, N., Javors, M. A., Walter, C. A., Nelson, J. F., Ikeno, Y., Vanremmen, H., Richardson, A. G., Austad, S. N., Strong, J. R., Hornsby, P. J., Walter, C. A., Sharp, D., Vijg, J. N. M. N., Firulli, A. B., Herman, B. A., Reddick, R., Bowman, B., Yu, B., Masoro, E. & Hornsby, P. J.

National Institutes of Health

7/10/956/30/20

Project: Research project

Shock
Research Personnel
Research
Rodentia
Genetically Modified Animals

Research Output 1997 2019

  • 34 h-Index
  • 83 Article
  • 1 Chapter
  • 1 Review article
13 Citations (Scopus)

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis

Ogrodnik, M., Zhu, Y., Langhi, L. G. P., Tchkonia, T., Krüger, P., Fielder, E., Victorelli, S., Ruswhandi, R. A., Giorgadze, N., Pirtskhalava, T., Podgorni, O., Enikolopov, G., Johnson, K. O., Xu, M., Inman, C., Palmer, A. K., Schafer, M., Weigl, M., Ikeno, Y., Burns, T. C. & 4 others, Passos, J. F., von Zglinicki, T., Kirkland, J. L. & Jurk, D., May 7 2019, In : Cell Metabolism. 29, 5, p. 1061-1077.e8

Research output: Contribution to journalArticle

Open Access
Cell Aging
Neurogenesis
Anxiety
Obesity
Obese Mice
1 Citation (Scopus)

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis

Ogrodnik, M., Zhu, Y., Langhi, L. G. P., Tchkonia, T., Krüger, P., Fielder, E., Victorelli, S., Ruswhandi, R. A., Giorgadze, N., Pirtskhalava, T., Podgorni, O., Enikolopov, G., Johnson, K. O., Xu, M., Inman, C., Palmer, A. K., Schafer, M., Weigl, M., Ikeno, Y., Burns, T. C. & 4 others, Passos, J. F., von Zglinicki, T., Kirkland, J. L. & Jurk, D., Jan 1 2019, (Accepted/In press) In : Cell Metabolism.

Research output: Contribution to journalArticle

Manuscripts
Cell Aging
Neurogenesis
Publications
Anxiety
34 Citations (Scopus)

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study

Justice, J. N., Nambiar, A. M., Tchkonia, T., LeBrasseur, N. K., Pascual, R., Hashmi, S. K., Prata, L., Masternak, M. M., Kritchevsky, S. B., Musi, N. & Kirkland, J. L., Jan 1 2019, (Accepted/In press) In : EBioMedicine.

Research output: Contribution to journalArticle

Idiopathic Pulmonary Fibrosis
Quercetin
Labels
Cell Aging
Phenotype

Press/Media

GSE62365 RIP-CHIP data from CNOT6L WT and KO hepatocytes

Masahiro Morita

3/29/19

1 item of Media coverage

Press/Media: Press / Media

Cover Story ; Staying active, more and more Americans are reaching 100

Nicolas Musi

2/20/19

1 item of Media coverage

Press/Media: Press / Media

Scientists find way to delay aging with new anti-aging therapy

Nicolas Musi

2/19/19

1 item of Media coverage

Press/Media: Press / Media