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  • 2020

    Acanthosis nigricans as a composite marker of cardiometabolic risk and its complex association with obesity and insulin resistance in Mexican American children

    Lopez-Alvarenga, J. C., Chittoor, G., Paul, S. F. D., Puppala, S., Farook, V. S., Fowler, S. P., Resendez, R. G., Hernandez-Ruiz, J., Diaz-Badillo, A., Salazar, D., Garza, D. D., Lehman, D. M., Mummidi, S., Arya, R., Jenkinson, C. P., Lynch, J. L., DeFronzo, R. A., Blangero, J., Hale, D. E. & Duggirala, R., Oct 2020, In: PloS one. 15, 10 October, e0240467.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • A structural variation reference for medical and population genetics

    Genome Aggregation Database Consortium & Genome Aggregation Database Production Team, May 28 2020, In: Nature. 581, 7809, p. 444-451 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    29 Scopus citations
  • Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

    Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, Dec 1 2020, In: Nature communications. 11, 1, 2523.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Evaluating drug targets through human loss-of-function genetic variation

    Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, May 28 2020, In: Nature. 581, 7809, p. 459-464 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

    Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, Dec 1 2020, In: Nature communications. 11, 1, 2539.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • Neurocognitive impairment in type 2 diabetes: evidence for shared genetic aetiology

    Mollon, J., Curran, J. E., Mathias, S. R., Knowles, E. E. M., Carlisle, P., Fox, P. T., Olvera, R. L., Göring, H. H. H., Rodrigue, A., Almasy, L., Duggirala, R., Blangero, J. & Glahn, D. C., May 1 2020, In: Diabetologia. 63, 5, p. 977-986 10 p.

    Research output: Contribution to journalArticlepeer-review

  • Rapid, Phase-free Detection of Long Identity-by-Descent Segments Enables Effective Relationship Classification

    Seidman, D. N., Shenoy, S. A., Kim, M., Babu, R., Woods, I. G., Dyer, T. D., Lehman, D. M., Curran, J. E., Duggirala, R., Blangero, J. & Williams, A. L., Apr 2 2020, In: American Journal of Human Genetics. 106, 4, p. 453-466 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • The effect of LRRK2 loss-of-function variants in humans

    Genome Aggregation Database Production Team, Genome Aggregation Database Consortium & 23andMe Research Team, Jun 1 2020, In: Nature Medicine. 26, 6, p. 869-877 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • The mutational constraint spectrum quantified from variation in 141,456 humans

    Genome Aggregation Database Consortium, May 28 2020, In: Nature. 581, 7809, p. 434-443 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    301 Scopus citations
  • Transcript expression-aware annotation improves rare variant interpretation

    Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, May 28 2020, In: Nature. 581, 7809, p. 452-458 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • Using the Schmahmann Syndrome Scale to Assess Cognitive Impairment in Young Adults with Metabolic Syndrome: a Hypothesis-Generating Report

    Kotkowski, E., Price, L. R., Blevins, C. J., Franklin, C. G., Woolsey, M. D., DeFronzo, R. A., Blangero, J., Duggirala, R., Glahn, D. C., Schmahmann, J. D. & Fox, P. T., 2020, (Accepted/In press) In: Cerebellum.

    Research output: Contribution to journalArticlepeer-review

  • 2019

    A QTL on chromosome 3q23 influences processing speed in humans

    Knowles, E. E. M., Mathias, S. R., Mollon, J., Rodrigue, A., Koenis, M. M. G., Dyer, T. D., Goring, H. H. H., Curran, J. E., Olvera, R. L., Duggirala, R., Almasy, L., Blangero, J. & Glahn, D. C., Apr 2019, In: Genes, Brain and Behavior. 18, 4, e12530.

    Research output: Contribution to journalArticlepeer-review

  • Crossover interference and sex-specific genetic maps shape identical by descent sharing in close relatives

    Caballero, M., Seidman, D. N., Qiao, Y., Sannerud, J., Dyer, T. D., Lehman, D. M., Curran, J. E., Duggirala, R., Blangero, J., Carmi, S. & Williams, A. L., 2019, In: PLoS Genetics. 15, 12, e1007979.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

    Broad Genomics Platform, DiscovEHR Collaboration, CHARGE, LuCamp, ProDiGY, GoT2D, ESP, SIGMA-T2D, T2D-GENES & AMP-T2D-GENES, Jun 6 2019, In: Nature. 570, 7759, p. 71-76 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    49 Scopus citations
  • Family-based analyses reveal novel genetic overlap between cytokine interleukin-8 and risk for suicide attempt

    Knowles, E. E. M., Curran, J. E., Göring, H. H. H., Mathias, S. R., Mollon, J., Rodrigue, A., Olvera, R. L., Leandro, A., Duggirala, R., Almasy, L., Blangero, J. & Glahn, D. C., Aug 2019, In: Brain, Behavior, and Immunity. 80, p. 292-299 8 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • Human Cortical Thickness Organized into Genetically-determined Communities across Spatial Resolutions

    Alexander-Bloch, A. F., Mathias, S. R., Fox, P. T., Olvera, R. L., Göring, H. H. H., Duggirala, R., Curran, J. E., Blangero, J. & Glahn, D. C., 2019, In: Cerebral Cortex. 29, 1, p. 106-118 13 p.

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations
  • JC viruria is associated with reduced risk of diabetic kidney disease

    Family Investigation of Nephropathy and Diabetes (FIND Consortium), Jun 1 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 6, p. 2286-2294 9 p.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma

    National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium, Dec 2019, In: Chest. 156, 6, p. 1068-1079 12 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • 2018

    Deep-coverage whole genome sequences and blood lipids among 16,324 individuals

    NHLBI TOPMed Lipids Working Group, Dec 1 2018, In: Nature communications. 9, 1, 3391.

    Research output: Contribution to journalArticlepeer-review

    51 Scopus citations
  • Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

    Zekavat, S. M., Ruotsalainen, S., Handsaker, R. E., Alver, M., Bloom, J., Poterba, T., Seed, C., Ernst, J., Chaffin, M., Engreitz, J., Peloso, G. M., Manichaikul, A., Yang, C., Ryan, K. A., Fu, M., Johnson, W. C., Tsai, M., Budoff, M., Ramachandran, V. S., Cupples, L. A. & 323 others, Rotter, J. I., Rich, S. S., Post, W., Mitchell, B. D., Correa, A., Metspalu, A., Wilson, J. G., Salomaa, V., Kellis, M., Daly, M. J., Neale, B. M., McCarroll, S., Surakka, I., Esko, T., Ganna, A., Ripatti, S., Kathiresan, S., Natarajan, P., Abe, N., Abecasis, G., Albert, C., Allred, N. P., Almasy, L., Alonso, A., Ament, S., Anderson, P., Anugu, P., Applebaum-Bowden, D., Arking, D., Arnett, D. K., Ashley-Koch, A., Aslibekyan, S., Assimes, T., Auer, P., Avramopoulos, D., Barnard, J., Barnes, K., Barr, R. G., Barron-Casella, E., Beaty, T., Becker, D., Becker, L., Beer, R., Begum, F., Beitelshees, A., Benjamin, E., Bezerra, M., Bielak, L., Bis, J., Blackwell, T., Blangero, J., Boerwinkle, E., Borecki, I., Bowler, R., Brody, J., Broeckel, U., Broome, J., Bunting, K., Burchard, E., Cardwell, J., Carty, C., Casaburi, R., Casella, J., Chang, C., Chasman, D., Chavan, S., Chen, B. J., Chen, W. M., Chen, Y. D. I., Cho, M., Choi, S. H., Chuang, L. M., Chung, M., Cornell, E., Crandall, C., Crapo, J., Curran, J., Curtis, J., Custer, B., Damcott, C., Darbar, D., Das, S., David, S., Davis, C., Daya, M., Andrade, M. D., Debaun, M., Deka, R., Demeo, D., Devine, S., Do, R., Duan, Q., Duggirala, R., Durda, P., Dutcher, S., Eaton, C., Ekunwe, L., Ellinor, P., Emery, L., Farber, C., Farnam, L., Fingerlin, T., Flickinger, M., Fornage, M., Franceschini, N., Fullerton, S. M., Fulton, L., Gabriel, S., Gan, W., Gao, Y., Gass, M., Gelb, B., Geng, X., Germer, S., Gignoux, C., Gladwin, M., Glahn, D., Gogarten, S., Gong, D. W., Goring, H., Gu, C. C., Guan, Y., Guo, X., Haessler, J., Hall, M., Harris, D., Hawley, N., He, J., Heavner, B., Heckbert, S., Hernandez, R., Herrington, D., Hersh, C., Hidalgo, B., Hixson, J., Hokanson, J., Hong, E., Hoth, K., Hsiung, C., Huston, H., Hwu, C. M., Irvin, M. R., Jackson, R., Jain, D., Jaquish, C., Jhun, M. A., Johnsen, J., Johnson, A., Johnston, R., Jones, K., Kang, H. M., Kaplan, R., Kardia, S., Kaufman, L., Kelly, S., Kenny, E., Kessler, M., Khan, A., Kinney, G., Konkle, B., Kooperberg, C., Kramer, H., Krauter, S., Lange, C., Lange, E., Lange, L., Laurie, C., Laurie, C., Leboff, M., Lee, S. S., Lee, W. J., Lefaive, J., Levine, D., Levy, D., Lewis, J., Li, Y., Lin, H., Lin, K. H., Liu, S., Liu, Y., Loos, R., Lubitz, S., Lunetta, K., Luo, J., Mahaney, M., Make, B., Manson, J. A., Margolin, L., Martin, L., Mathai, S., Mathias, R., McArdle, P., McDonald, M. L., McFarland, S., McGarvey, S., Mei, H., Meyers, D. A., Mikulla, J., Min, N., Minear, M., Minster, R. L., Montasser, M. E., Musani, S., Mwasongwe, S., Mychaleckyj, J. C., Nadkarni, G., Naik, R., Nekhai, S., Nickerson, D., North, K., O'connell, J., O'connor, T., Ochs-Balcom, H., Pankow, J., Papanicolaou, G., Parker, M., Parsa, A., Penchev, S., Peralta, J. M., Perez, M., Perry, J., Peters, U., Peyser, P., Phillips, L., Phillips, S., Pollin, T., Becker, J. P., Boorgula, M. P., Preuss, M., Prokopenko, D., Psaty, B., Qasba, P., Qiao, D., Qin, Z., Rafaels, N., Raffield, L., Rao, D. C., Rasmussen-Torvik, L., Ratan, A., Redline, S., Reed, R., Regan, E., Reiner, A., Rice, K., Roden, D., Roselli, C., Ruczinski, I., Russell, P., Ruuska, S., Sakornsakolpat, P., Salimi, S., Salzberg, S., Sandow, K., Sankaran, V., Scheller, C., Schmidt, E., Schwander, K., Schwartz, D., Sciurba, F., Seidman, C., Sheehan, V., Shetty, A., Shetty, A., Sheu, W. H. H., Shoemaker, M. B., Silver, B., Silverman, E., Smith, J., Smith, J., Smith, N., Smith, T., Smoller, S., Snively, B., Sofer, T., Sotoodehnia, N., Stilp, A., Streeten, E., Sung, Y. J., Sylvia, J., Szpiro, A., Sztalryd, C., Taliun, D., Tang, H., Taub, M., Taylor, K., Taylor, S., Telen, M., Thornton, T. A., Tinker, L., Tirschwell, D., Tiwari, H., Tracy, R., Vaidya, D., Vandehaar, P., Vrieze, S., Walker, T., Wallace, R., Walts, A., Wan, E., Wang, F. F., Watson, K., Weeks, D. E., Weir, B., Weiss, S., Weng, L. C., Willer, C., Williams, K., Williams, L. K., Wilson, C., Wong, Q., Xu, H., Yanek, L., Yang, I., Yang, R., Zaghloul, N., Zhang, Y., Zhao, S. X., Zhao, W., Zheng, X., Zhi, D., Zhou, X., Zody, M. & Zoellner, S., Dec 1 2018, In: Nature communications. 9, 1, 2606.

    Research output: Contribution to journalArticlepeer-review

    23 Scopus citations
  • Disentangling the genetic overlap between cholesterol and suicide risk

    Knowles, E. E. M., Curran, J. E., Meikle, P. J., Huynh, K., Mathias, S. R., Göring, H. H. H., VandeBerg, J. L., Mahaney, M. C., Jalbrzikowski, M., Mosior, M. K., Michael, L. F., Olvera, R. L., Duggirala, R., Almasy, L., Glahn, D. C. & Blangero, J., Dec 1 2018, In: Neuropsychopharmacology. 43, 13, p. 2556-2563 8 p.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • 2017

    A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes

    Broad Genomics Platform, T2D-GENES Consortium, SIGMA T2D Genetics Consortium & Diabetes Prevention Program Research Group, Nov 1 2017, In: Diabetes. 66, 11, p. 2903-2914 12 p.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • A low-frequency inactivating AKT2 variant enriched in the finnish population is associated with fasting insulin levels and type 2 diabetes risk

    Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B. R., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., Depristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., de Angelis, M. H., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Hale, D. E., Fowler, S. P., Arya, R., Defronzo, R. A., Abboud, H. E., Syvänen, A. C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S. T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J. Y., Han, B. G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., E Mel Ander, O. L., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., U, J. L., Khor, C. C., Chia, K. S., Lim, W. Y., Cheng, C. Y., Chan, E., Shyong Tai, E., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Na Kravi C, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Kat, K. H., Farmer, A. J., Frayling, T. M., O’rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stan?cáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Antero Kesaniemi, Y., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., Jul 1 2017, In: Diabetes. 66, 7, p. 2019-2032 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    23 Scopus citations
  • Benchmarking relatedness inference methods with genome-wide data from thousands of relatives

    Ramstetter, M. D., Dyer, T. D., Lehman, D. M., Curran, J. E., Duggirala, R., Blangero, J., Mezey, J. G. & Williams, A. L., 2017, In: Genetics. 207, 1, p. 75-82 8 p.

    Research output: Contribution to journalArticlepeer-review

    21 Scopus citations
  • Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

    Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., Van De Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., De Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P. M., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., Dec 19 2017, In: Scientific Data. 4, 170179.

    Research output: Contribution to journalArticlepeer-review

    10 Scopus citations
  • Effects of conjugated linoleic acid and metformin on insulin sensitivity in obese children: Randomized clinical trial

    Garibay-Nieto, N., Queipo-García, G., Alvarez, F., Bustos, M., Villanueva, E., Ramírez, F., León, M., Laresgoiti-Servitje, E., Duggirala, R., Macías, T., Cuevas, S., Jalife, A., Fonseca-Sánchez, M., Serratos, F. & López-Alvarenga, J. C., Jan 1 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 1, p. 132-140 9 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees

    Jun, G., Manning, A., Almeida, M., Zawistowski, M., Wood, A. R., Teslovich, T. M., Fuchsberger, C., Feng, S., Cingolani, P., Gaulton, K. J., Dyer, T., Blackwell, T. W., Chen, H., Chines, P. S., Choi, S., Churchhouse, C., Fontanillas, P., King, R., Lee, S. Y., Lincoln, S. E. & 54 others, Trubetskoy, V., DePristo, M., Fingerlin, T., Grossman, R., Grundstad, J., Heath, A., Kim, J., Kim, Y. J., Laramie, J., Lee, J., Li, H., Liu, X., Livne, O., Locke, A. E., Maller, J., Mazur, A., Morris, A. P., Pollin, T. I., Ragona, D., Reich, D., Rivas, M. A., Scott, L. J., Sim, X., Tearle, R. G., Teo, Y. Y., Williams, A. L., Zöllner, S., Curran, J. E., Peralta, J., Akolkar, B., Bell, G. I., Burtt, N. P., Cox, N. J., Florez, J. C., Hanis, C. L., McKeon, C., Mohlke, K. L., Seielstad, M., Wilson, J. G., Atzmon, G., Below, J. E., Dupuis, J., Nicolae, D. L., Lehman, D., Park, T., Won, S., Sladek, R., Altshuler, D., McCarthy, M. I., Duggirala, R., Boehnke, M., Frayling, T. M., Abecasis, G. R. & Blangero, J., Jan 9 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 2, p. 379-384 6 p.

    Research output: Contribution to journalArticlepeer-review

    13 Scopus citations
  • Novel genetic loci associated with hippocampal volume

    Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J., Athanasiu, L. & 312 others, Axelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-Partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., MacAre, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., McKay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van Der Grond, J., Van Der Lee, S. J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., Decarli, C., Delanty, N., Depondt, C., Destefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, F. J., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Haren, N. E. M., Van 'T Ent, D., Van Tol, M. J., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., Jan 18 2017, In: Nature communications. 8, 13624.

    Research output: Contribution to journalArticlepeer-review

    109 Scopus citations
  • Shared Genetic Factors Influence Head Motion During MRI and Body Mass Index

    Hodgson, K., Poldrack, R. A., Curran, J. E., Knowles, E. E., Mathias, S., Göring, H. H. H., Yao, N., Olvera, R. L., Fox, P. T., Almasy, L., Duggirala, R., Barch, D. M., Blangero, J. & Glahn, D. C., Dec 1 2017, In: Cerebral cortex (New York, N.Y. : 1991). 27, 12, p. 5539-5546 8 p.

    Research output: Contribution to journalArticlepeer-review

    23 Scopus citations
  • The genetic basis of the comorbidity between cannabis use and major depression

    Hodgson, K., Almasy, L., Knowles, E. E. M., Kent, J. W., Curran, J. E., Dyer, T. D., Göring, H. H. H., Olvera, R. L., Woolsey, M. D., Duggirala, R., Fox, P. T., Blangero, J. & Glahn, D. C., Jan 1 2017, In: Addiction. 112, 1, p. 113-123 11 p.

    Research output: Contribution to journalArticlepeer-review

    9 Scopus citations
  • 2016

    Analysis of protein-coding genetic variation in 60,706 humans

    Lek, M., Karczewski, K. J., Minikel, E. V., Samocha, K. E., Banks, E., Fennell, T., O'Donnell-Luria, A. H., Ware, J. S., Hill, A. J., Cummings, B. B., Tukiainen, T., Birnbaum, D. P., Kosmicki, J. A., Duncan, L. E., Estrada, K., Zhao, F., Zou, J., Pierce-Hoffman, E., Berghout, J., Cooper, D. N. & 153 others, Deflaux, N., DePristo, M., Do, R., Flannick, J., Fromer, M., Gauthier, L., Goldstein, J., Gupta, N., Howrigan, D., Kiezun, A., Kurki, M. I., Moonshine, A. L., Natarajan, P., Orozco, L., Peloso, G. M., Poplin, R., Rivas, M. A., Ruano-Rubio, V., Rose, S. A., Ruderfer, D. M., Shakir, K., Stenson, P. D., Stevens, C., Thomas, B. P., Tiao, G., Tusie-Luna, M. T., Weisburd, B., Won, H. H., Yu, D., Altshuler, D. M., Ardissino, D., Boehnke, M., Danesh, J., Donnelly, S., Elosua, R., Florez, J. C., Gabriel, S. B., Getz, G., Glatt, S. J., Hultman, C. M., Kathiresan, S., Laakso, M., McCarroll, S., McCarthy, M. I., McGovern, D., McPherson, R., Neale, B. M., Palotie, A., Purcell, S. M., Saleheen, D., Scharf, J. M., Sklar, P., Sullivan, P. F., Tuomilehto, J., Tsuang, M. T., Watkins, H. C., Wilson, J. G., Daly, M. J., MacArthur, D. G., Abboud, H. E., Abecasis, G., Aguilar-Salinas, C. A., Arellano-Campos, O., Atzmon, G., Aukrust, I., Barr, C. L., Bell, G. I., Bergen, S., Bjørkhaug, L., Blangero, J., Bowden, D. W., Budman, C. L., Burtt, N. P., Centeno-Cruz, F., Chambers, J. C., Chambert, K., Clarke, R., Collins, R., Coppola, G., Córdova, E. J., Cortes, M. L., Cox, N. J., Duggirala, R., Farrall, M., Fernandez-Lopez, J. C., Fontanillas, P., Frayling, T. M., Freimer, N. B., Fuchsberger, C., García-Ortiz, H., Goel, A., Gómez-Vázquez, M. J., González-Villalpando, M. E., González-Villalpando, C., Grados, M. A., Groop, L., Haiman, C. A., Hanis, C. L., Hattersley, A. T., Henderson, B. E., Hopewell, J. C., Huerta-Chagoya, A., Islas-Andrade, S., Jacobs, S. B., Jalilzadeh, S., Jenkinson, C. P., Moran, J., Jiménez-Morale, S., Kähler, A., King, R. A., Kirov, G., Kooner, J. S., Kyriakou, T., Lee, J. Y., Lehman, D. M., Lyon, G., MacMahon, W., Magnusson, P. K., Mahajan, A., Marrugat, J., Martínez-Hernández, A., Mathews, C. A., McVean, G., Meigs, J. B., Meitinger, T., Mendoza-Caamal, E., Mercader, J. M., Mohlke, K. L., Moreno-Macías, H., Morris, A. P., Najmi, L. A., Njølstad, P. R., O'Donovan, M. C., Ordóñez-Sánchez, M. L., Owen, M. J., Park, T., Pauls, D. L., Posthuma, D., Revilla-Monsalve, C., Riba, L., Ripke, S., Rodríguez-Guillén, R., Rodríguez-Torres, M., Sandor, P., Seielstad, M., Sladek, R., Soberón, X., Spector, T. D., Tai, S. E., Teslovich, T. M., Walford, G., Wilkens, L. R. & Williams, A. L., Aug 17 2016, In: Nature. 536, 7616, p. 285-291 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5007 Scopus citations
  • Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept

    Psychosis Endophenotypes International Consortium, Feb 23 2016, In: Nature Neuroscience. 19, 3, p. 420-431 12 p.

    Research output: Contribution to journalArticlepeer-review

    122 Scopus citations
  • Genome- and epigenome-wide association study of hypertriglyceridemic waist in Mexican American families

    Mamtani, M., Kulkarni, H., Dyer, T. D., Göring, H. H. H., Neary, J. L., Cole, S. A., Kent, J. W., Kumar, S., Glahn, D. C., Mahaney, M. C., Comuzzie, A. G., Almasy, L., Curran, J. E., Duggirala, R., Blangero, J. & Carless, M. A., Jan 20 2016, In: Clinical Epigenetics. 8, 1, p. 1-14 14 p., 6.

    Research output: Contribution to journalArticlepeer-review

    28 Scopus citations
  • Genome-wide significant loci for addiction and anxiety

    Hodgson, K., Almasy, L., Knowles, E. E. M., Kent, J. W., Curran, J. E., Dyer, T. D., Göring, H. H. H., Olvera, R. L., Fox, P. T., Pearlson, G. D., Krystal, J. H., Duggirala, R., Blangero, J. & Glahn, D. C., Aug 1 2016, In: European Psychiatry. 36, p. 47-54 8 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • GWAS and transcriptional analysis prioritize ITPR1 and CNTN4 for a serum uric acid 3p26 QTL in Mexican Americans

    Chittoor, G., Kent, J. W., Almeida, M., Puppala, S., Farook, V. S., Cole, S. A., Haack, K., Göring, H. H. H., MacCluer, J. W., Curran, J. E., Carless, M. A., Johnson, M. P., Moses, E. K., Almasy, L., Mahaney, M. C., Lehman, D. M., Duggirala, R., Comuzzie, A. G., Blangero, J. & Voruganti, V. S., Apr 2 2016, In: BMC genomics. 17, 1, 276.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • Lack of Association between SLC30A8 Variants and Type 2 Diabetes in Mexican American Families

    Kulkarni, H., Mamtani, M., Peralta, J. M., Diego, V., Dyer, T. D., Goring, H., Almasy, L., Mahaney, M. C., Williams-Blangero, S., Duggirala, R., Curran, J. E. & Blangero, J., 2016, In: Journal of diabetes research. 2016, 6463214.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Novel genetic loci underlying human intracranial volume identified through genome-wide association

    Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Rentería, M. E., Trompet, S., Arias-Vasquez, A., Seshadri, S., Desrivières, S., Beecham, A. H., Jahanshad, N., Wittfeld, K., Van Der Lee, S. J., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S. & 322 others, Armstrong, N. J., Athanasiu, L., Axelsson, T., Beiser, A., Bernard, M., Bis, J. C., Blanken, L. M. E., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chauhan, G., Chen, Q., Ching, C. R. K., Cuellar-Partida, G., Braber, A. D., Doan, N. T., Ehrlich, S., Filippi, I., Ge, T., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Greven, C. U., Grimm, O., Griswold, M. E., Guadalupe, T., Hass, J., Haukvik, U. K., Hilal, S., Hofer, E., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liao, J., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A., Matarin, M., Mather, K. A., Mattheisen, M., Mazoyer, B., McKay, D. R., McWhirter, R., Milaneschi, Y., Mirza-Schreiber, N., Muetzel, R. L., Maniega, S. M., Nho, K., Nugent, A. C., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pappa, I., Pirpamer, L., Pudas, S., Pütz, B., Rajan, K. B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Thomson, R., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Vaidya, D., Van Der Grond, J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Woldehawariat, G., Wolf, C., Wolfers, T., Xu, B., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Aggarwal, N. T., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Chen, C., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Delanty, N., Depondt, C., Destefano, A. L., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Erk, S., Espeseth, T., Evans, D. A., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Grabe, H. J., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Pol, H. E. H., Ikeda, M., Ikram, M. K., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Longstreth, W. T., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, K. L., McMahon, F. J., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schofield, P. R., Sigurdsson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Srikanth, V., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Tiemeier, H., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Duijn, C. M., Van Haren, N. E. M., Van't Ent, D., Van Tol, M. J., Vardarajan, B. N., Veltman, D. J., Vernooij, M. W., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, H. R., Zonderman, A. B., Deary, I. J., Decarli, C., Schmidt, H., Martin, N. G., De Craen, A. J. M., Wright, M. J., Launer, L. J., Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S. E., Ikram, M. A. & Thompson, P. M., Dec 1 2016, In: Nature Neuroscience. 19, 12, p. 1569-1582 14 p.

    Research output: Contribution to journalArticlepeer-review

    101 Scopus citations
  • Selecting SNPs informative for African, American Indian and European Ancestry: Application to the Family Investigation of Nephropathy and Diabetes (FIND)

    Williams, R. C., Elston, R. C., Kumar, P., Knowler, W. C., Abboud, H. E., Adler, S., Bowden, D. W., Divers, J., Freedman, B. I., Igo, R. P., Ipp, E., Iyengar, S. K., Kimmel, P. L., Klag, M. J., Kohn, O., Langefeld, C. D., Leehey, D. J., Nelson, R. G., Nicholas, S. B., Pahl, M. V. & 108 others, Parekh, R. S., Rotter, J. I., Schelling, J. R., Sedor, J. R., Shah, V. O., Smith, M. W., Taylor, K. D., Thameem, F., Thornley-Brown, D., Winkler, C. A., Guo, X., Zager, P., Hanson, R. L., FIND Research Group, R. G., S.K. Iyengar, I., Elston, R. C., Goddard, K. A. B., Olson, J. M., Ialacci, S., Fondran, J., Horvath, A., Igo, R., Jun, G., Kramp, K., Molineros, J., Quade, S. R. E., Schelling, J., Pickens, A., Humbert, L., Getz-Fradley, L., Adler, S., Ipp, E., Pahl, M., Seldin, M. F., Snyder, S., Tayek, J., Hernandez, E., LaPage, J., Garcia, C., Gonzalez, J., Aguilar, M., Parekh, R., Kao, L., Meoni, L., Whitehead, T., Chester, J., Knowler, W. C., Hanson, R. L., Nelson, R. G., Wolford, J., Jones, L., Juan, R., Lovelace, R., Luethe, C., Phillips, L. M., Sewemaenewa, J., Sili, I., Waseta, B., Saad, M. F., Nicholas, S. B., Chen, Y. D. I., Guo, X., Rotter, J., Taylor, K., Budgett, M., Hariri, F., Zager, P., Shah, V., Scavini, M., Bobelu, A., Abboud, H., Arar, N., Duggirala, R., Kasinath, B. S., Thameem, F., Stern, M., Freedman, B. I., Bowden, D. W., Langefeld, C. D., Satko, S. C., Rich, S. S., Warren, S., Viverette, S., Brooks, G., Young, R., Spainhour, M., Winkler, C., Smith, M. W., Thompson, M., Hanson, R., Kessing, B., Leehey, D. J., Barone, G., Thornley-Brown, D., Jefferson, C., Kohn, O. F., Brown, C. S., Briggs, J. P., Kimmel, P. L., Rasooly, R., D. Warnock, W., Cardon, L., Chakraborty, R., Dunston, G. M., Hostetter, T., O'Brien, S. J., Rioux, J. & Spielman, R., May 4 2016, In: BMC genomics. 17, 1, 325.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • The genetic architecture of type 2 diabetes

    Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F., Highland, H. M. & 281 others, Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., Van De Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Van Der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njolstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jorgensen, M. E., Jorgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., De Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I., Jul 11 2016, In: Nature. 536, 7614, p. 41-47 7 p.

    Research output: Contribution to journalArticlepeer-review

    510 Scopus citations
  • Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms

    T2D-GENES Consortium, May 15 2016, In: Human molecular genetics. 25, 10, p. 2070-2081 12 p.

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations
  • 2015

    A new strategy for enhancing imputation quality of rare variants from next-generation sequencing data via combining SNP and exome chip data

    T2D-Genes Consortium and Taesung Park, Dec 29 2015, In: BMC genomics. 16, 1, 1109.

    Research output: Contribution to journalArticlepeer-review

    6 Scopus citations
  • Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND)

    Iyengar, S. K., Sedor, J. R., Freedman, B. I., Kao, W. H. L., Kretzler, M., Keller, B. J., Abboud, H. E., Adler, S. G., Best, L. G., Bowden, D. W., Burlock, A., Chen, Y. D. I., Cole, S. A., Comeau, M. E., Curtis, J. M., Divers, J., Drechsler, C., Duggirala, R., Elston, R. C., Guo, X. & 39 others, Huang, H., Hoffmann, M. M., Howard, B. V., Ipp, E., Kimmel, P. L., Klag, M. J., Knowler, W. C., Kohn, O. F., Leak, T. S., Leehey, D. J., Li, M., Malhotra, A., März, W., Nair, V., Nelson, R. G., Nicholas, S. B., O’Brien, S. J., Pahl, M. V., Parekh, R. S., Pezzolesi, M. G., Rasooly, R. S., Rotimi, C. N., Rotter, J. I., Schelling, J. R., Seldin, M. F., Shah, V. O., Smiles, A. M., Smith, M. W., Taylor, K. D., Thameem, F., Thornley-Brown, D. P., Truitt, B. J., Wanner, C., Weil, E. J., Winkler, C. A., Zager, P. G., Igo, R. P., Hanson, R. L. & Langefeld, C. D., Aug 1 2015, In: PLoS Genetics. 11, 8, e1005352.

    Research output: Contribution to journalArticlepeer-review

    60 Scopus citations
  • Identification and Functional Characterization of G6PC2 Coding Variants Influencing Glycemic Traits Define an Effector Transcript at the G6PC2-ABCB11 Locus

    Mahajan, A., Sim, X., Ng, H. J., Manning, A., Rivas, M. A., Highland, H. M., Locke, A. E., Grarup, N., Im, H. K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K. J., Teslovich, T. M., Rayner, N. W., Robertson, N. R., Beer, N. L., Rundle, J. K., Bork-Jensen, J. & 243 others, Ladenvall, C., Blancher, C., Buck, D., Buck, G., Burtt, N. P., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Syvänen, A. C., Trakalo, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Hanis, C. L., Seielstad, M., Wilson, J. G., Christensen, C., Brandslund, I., Rauramaa, R., Surdulescu, G. L., Doney, A. S. F., Lannfelt, L., Linneberg, A., Isomaa, B., Tuomi, T., Jørgensen, M. E., Jørgensen, T., Kuusisto, J., Uusitupa, M., Salomaa, V., Spector, T. D., Morris, A. D., Palmer, C. N. A., Collins, F. S., Mohlke, K. L., Bergman, R. N., Ingelsson, E., Lind, L., Tuomilehto, J., Hansen, T., Watanabe, R. M., Prokopenko, I., Dupuis, J., Karpe, F., Groop, L., Laakso, M., Pedersen, O., Florez, J. C., Morris, A. P., Altshuler, D., Meigs, J. B., Boehnke, M., McCarthy, M. I., Lindgren, C. M., Gloyn, A. L., Abboud, H. E., Afzal, U., Aguilar, D., Arya, R., Atzmon, G., Aung, T., Banks, E., Barroso, I., Barzilai, N., Below, J. E., Bharadwaj, D., Blackwell, T. W., Bonnycastle, L. L., Bowden, D., Carey, J., Carneiro, M. O., Chambers, J. C., Chan, E., Chan, J., Chandak, G. R., Chen, P., Chen, Y., Chen, H., Cheng, C. Y., Chia, K. S., Cho, Y. S., Correa, A., Curran, J. E., Daly, M. J., Day-Williams, A. G., DeFronzo, R. A., DePristo, M., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Esko, T., Fadista, J., Farjoun, Y., Farmer, A. J., Farook, V. S., Fennell, T., Ferreira, T., Fingerlin, T., Forsén, T., Fowler, S. P., Franks, P. W., Frayling, T. M., Freedman, B. I., Froguel, P., Gamazon, E. R., Gieger, C., Glaser, B., Go, M. J., Goldstein, J. I., Grallert, H., Grant, G., Green, T., Griswold, M., Hale, D. E., Han, B. G., Hartl, C., Hattersley, A. T., Hicks, P. J., Hodgkiss, D., Horikoshi, M., Hrabé de Angelis, M., Hu, C., Hu, F. B., Huh, I., Kamran Ikram, M., Illig, T., Jablonski, K. A., Jenkinson, C. P., Jia, W., Kang, H. M., Khor, C. C., Kim, Y., Kim, Y. J., Kim, B. J., Kinnunen, L., Kooner, J. S., Kravic, J., Kriebel, J., Kumar, A., Kumar, S., Kuulasmaa, T., Kwon, M. S., Langenberg, C., Lauritzen, T., Lee, S., Lee, J., Lee, J., Lee, J. Y., Lehman, D. M., Lehne, B., Levy, J. C., Li, J., Liang, L., Lim, W. Y., Lin, K. H., Liu, J., Loh, M., Ma, R. C. W., Ma, C., Mägi, R., Maguire, J., Maxwell, T. J., McVean, G., Meisinger, C., Meitinger, T., Melander, O., Metspalu, A., Mihailov, E., Milani, L., Moutsianas, L., Müller-Nurasyid, M., K. Musani, S., Nagai, Y., Narisu, N., Neale, B. M., Ng, M. C. Y., Nilsson, P., O'Rahilly, S. P., Orho-Melander, M., Owen, K. R., Palmer, N. D., Park, T., Pasko, D., Pearson, R. D., Perry, J. R. B., Peters, A., Pollin, T. I., Poplin, R., Prabhakaran, D., Puppala, S., Purcell, S., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Rosengren, A. H., Sandhu, M., Schwarzmayr, T., Scott, L. J., Scott, R. A., Scott, J., Scott, W. R., Sehmi, J., Shakir, K., Sladek, R., Smith, J. D., Stancáková, A., Strauch, K., Strom, T. M., Swift, A., Tai, E. S., Tajes, J. F., Tan, S. T., Tandon, N., Taylor, H. A., Teo, Y. Y., Thameem, F., Thorand, B., van de Bunt, M., Varga, T. V., Walker, M., Wareham, N. J., Welch, R. P., Wieland, T., Wilson, G., Wong, T. Y., Wood, A. R., Yoon, J., Zeggini, E. & Zhang, W., Jan 27 2015, In: PLoS Genetics. 11, 1, e1004876.

    Research output: Contribution to journalArticlepeer-review

    59 Scopus citations
  • Shared genetic variance between obesity and white matter integrity in Mexican Americans

    Spieker, E. A., Kochunov, P., Rowland, L. M., Sprooten, E., Winkler, A. M., Olvera, R. L., Almasy, L., Duggirala, R., Fox, P. T., Blangero, J., Glahn, D. C. & Curran, J. E., 2015, In: Frontiers in Genetics. 5, FEB, 00026.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes

    Wood, A. R., Tuke, M. A., Nalls, M., Hernandez, D., Raphael Gibbs, J., Lin, H., Xu, C. S., Li, Q., Shen, J., Jun, G., Almeida, M., Tanaka, T., Perry, J. R. B., Gaulton, K., Rivas, M., Pearson, R., Curran, J. E., Johnson, M. P., Göring, H. H. H., Duggirala, R. & 9 others, Blangero, J., Mccarthy, M. I., Bandinelli, S., Murray, A., Weedon, M. N., Singleton, A., Melzer, D., Ferrucci, L. & Frayling, T. M., Mar 1 2015, In: Human molecular genetics. 24, 5, p. 1504-1512 9 p.

    Research output: Contribution to journalArticlepeer-review

    6 Scopus citations
  • 2014

    Loss-of-function mutations in SLC30A8 protect against type 2 diabetes

    Flannick, J., Thorleifsson, G., Beer, N. L., Jacobs, S. B. R., Grarup, N., Burtt, N. P., Mahajan, A., Fuchsberger, C., Atzmon, G., Benediktsson, R., Blangero, J., Bowden, D. W., Brandslund, I., Brosnan, J., Burslem, F., Chambers, J., Cho, Y. S., Christensen, C., Douglas, D. A., Duggirala, R. & 60 others, Dymek, Z., Farjoun, Y., Fennell, T., Fontanillas, P., Forsén, T., Gabriel, S., Glaser, B., Gudbjartsson, D. F., Hanis, C., Hansen, T., Hreidarsson, A. B., Hveem, K., Ingelsson, E., Isomaa, B., Johansson, S., Jørgensen, T., Jørgensen, M. E., Kathiresan, S., Kong, A., Kooner, J., Kravic, J., Laakso, M., Lee, J. Y., Lind, L., Lindgren, C. M., Linneberg, A., Masson, G., Meitinger, T., Mohlke, K. L., Molven, A., Morris, A. P., Potluri, S., Rauramaa, R., Ribel-Madsen, R., Richard, A. M., Rolph, T., Salomaa, V., Segrè, A. V., Skärstrand, H., Steinthorsdottir, V., Stringham, H. M., Sulem, P., Tai, E. S., Teo, Y. Y., Teslovich, T., Thorsteinsdottir, U., Trimmer, J. K., Tuomi, T., Tuomilehto, J., Vaziri-Sani, F., Voight, B. F., Wilson, J. G., Boehnke, M., McCarthy, M. I., Njølstad, P. R., Pedersen, O., Groop, L., Cox, D. R., Stefansson, K. & Altshuler, D., Apr 2014, In: Nature Genetics. 46, 4, p. 357-363 7 p.

    Research output: Contribution to journalArticlepeer-review

    290 Scopus citations
  • Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

    The MAGIC investigators & The GIANT consortium, Aug 7 2014, In: PLoS Genetics. 10, 8, e1004517.

    Research output: Contribution to journalArticlepeer-review

    115 Scopus citations
  • Multi-site study of additive genetic effects on fractional anisotropy of cerebral white matter: Comparing meta and megaanalytical approaches for data pooling

    Kochunov, P., Jahanshad, N., Sprooten, E., Nichols, T. E., Mandl, R. C., Almasy, L., Booth, T., Brouwer, R. M., Curran, J. E., de Zubicaray, G. I., Dimitrova, R., Duggirala, R., Fox, P. T., Elliot Hong, L., Landman, B. A., Lemaitre, H., Lopez, L. M., Martin, N. G., McMahon, K. L., Mitchell, B. D. & 21 others, Olvera, R. L., Peterson, C. P., Starr, J. M., Sussmann, J. E., Toga, A. W., Wardlaw, J. M., Wright, M. J., Wright, S. N., Bastin, M. E., McIntosh, A. M., Boomsma, D. I., Kahn, R. S., den Braber, A., de Geus, E. J. C., Deary, I. J., Hulshoff Pol, H. E., Williamson, D. E., Blangero, J., van 't Ent, D., Thompson, P. M. & Glahn, D. C., 2014, In: NeuroImage. 95, p. 136-150 15 p.

    Research output: Contribution to journalArticlepeer-review

    73 Scopus citations
  • Pedigree-based random effect tests to screen gene pathways

    Almeida, M., Peralta, J. M., Farook, V., Puppala, S., Kent, J. W., Duggirala, R. & Blangero, J., Jun 17 2014, In: BMC Proceedings. 8, S100.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes

    NHGRI JHS/FHS Allelic Spectrum Project, GoT2D Consortium, SIGMA T2D Consortium & T2D-GENES Consortium, 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 36, p. 13127-13132 6 p.

    Research output: Contribution to journalArticlepeer-review

    92 Scopus citations