Regional Academic Health Center, Harlingen

Search results

  • 2021
    Open Access
  • Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program

    TOPMed Sleep Working Group & NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Dec 2021, In: Genome Medicine. 13, 1, 136.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • 2020

    A structural variation reference for medical and population genetics

    Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, May 28 2020, In: Nature. 581, 7809, p. 444-451 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    83 Scopus citations
  • Characterising the loss-of-function impact of 5’ untranslated region variants in 15,708 individuals

    Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, Dec 1 2020, In: Nature communications. 11, 1, 2523.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • Evaluating drug targets through human loss-of-function genetic variation

    Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, May 28 2020, In: Nature. 581, 7809, p. 459-464 6 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    25 Scopus citations
  • Landscape of multi-nucleotide variants in 125,748 human exomes and 15,708 genomes

    Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, Dec 1 2020, In: Nature communications. 11, 1, 2539.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    19 Scopus citations
  • Neurocognitive impairment in type 2 diabetes: evidence for shared genetic aetiology

    Mollon, J., Curran, J. E., Mathias, S. R., Knowles, E. E. M., Carlisle, P., Fox, P. T., Olvera, R. L., Göring, H. H. H., Rodrigue, A., Almasy, L., Duggirala, R., Blangero, J. & Glahn, D. C., May 1 2020, In: Diabetologia. 63, 5, p. 977-986 10 p.

    Research output: Contribution to journalArticlepeer-review

  • The effect of LRRK2 loss-of-function variants in humans

    Genome Aggregation Database Production Team, Genome Aggregation Database Consortium & 23andMe Research Team, Jun 1 2020, In: Nature Medicine. 26, 6, p. 869-877 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    21 Scopus citations
  • The mutational constraint spectrum quantified from variation in 141,456 humans

    Genome Aggregation Database Consortium, May 28 2020, In: Nature. 581, 7809, p. 434-443 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    875 Scopus citations
  • Transcript expression-aware annotation improves rare variant interpretation

    Genome Aggregation Database Production Team & Genome Aggregation Database Consortium, May 28 2020, In: Nature. 581, 7809, p. 452-458 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    16 Scopus citations
  • 2019

    Evidence for genetic correlation between human cerebral white matter microstructure and inflammation

    Rodrigue, A. L., Knowles, E. E. M., Mollon, J., Mathias, S. R., Koenis, M. M. G., Peralta, J. M., Leandro, A. C., Fox, P. T., Sprooten, E., Kochunov, P., Olvera, R. L., Duggirala, R., Almasy, L., Curran, J. E., Blangero, J. & Glahn, D. C., Oct 2019, In: Human Brain Mapping. 40, 14, p. 4180-4191 12 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • Human Cortical Thickness Organized into Genetically-determined Communities across Spatial Resolutions

    Alexander-Bloch, A. F., Mathias, S. R., Fox, P. T., Olvera, R. L., Göring, H. H. H., Duggirala, R., Curran, J. E., Blangero, J. C. & Glahn, D. C., Jan 1 2019, In: Cerebral Cortex. 29, 1, p. 106-118 13 p.

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations
  • JC viruria is associated with reduced risk of diabetic kidney disease

    Family Investigation of Nephropathy and Diabetes (FIND Consortium), Jun 1 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 6, p. 2286-2294 9 p.

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations
  • Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma

    National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium, Dec 2019, In: Chest. 156, 6, p. 1068-1079 12 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • 2018

    Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population

    International IBD Genetics Consortium, NIDDK IBD Genetics Consortium & T2D-GENES Consortium, May 2018, In: PLoS Genetics. 14, 5, e1007329.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    28 Scopus citations
  • 2017

    A loss-of-function splice acceptor variant in igf2 is protective for type 2 diabetes

    Mercader, J. M., Liao, R. G., Bell, A. D., Dymek, Z., Estrada, K., Tukiainen, T., Huerta-Chagoya, A., Moreno-Macías, H., Jablonski, K. A., Hanson, R. L., Walford, G. A., Moran, I., Chen, L., Agarwala, V., Ordoñez-Sánchez, M. L., Rodríguez-Guillen, R., Rodríguez-Torres, M., Segura-Kato, Y., García-Ortiz, H., Centeno-Cruz, F. & 58 others, Barajas-Olmos, F., Caulkins, L., Puppala, S., Fontanillas, P., Williams, A. L., Bonàs-Guarch, S., Hartl, C., Ripke, S., Tooley, K., Lane, J., Zerrweck, C., Martínez-Hernández, A., Córdova, E. J., Mendoza-Caamal, E., Contreras-Cubas, C., González-Villalpando, M. E., Cruz-Bautista, I., Muñoz-Hernández, L., Gómez-Velasco, D., Alvirde, U., Henderson, B. E., Wilkens, L. R., Marchand, L. L., Arellano-Campos, O., Riba, L., Harden, M., Gabriel, S., Abboud, H. E., Cortes, M. L., Revilla-Monsalve, C., Islas-Andrade, S., Soberon, X., Curran, J. E., Jenkinson, C. P., Defronzo, R. A., Lehman, D. M., Hanis, C. L., Bell, G. I., Boehnke, M., Blangero, J., Duggirala, R., Saxena, R., Macarthur, D., Ferrer, J., McCarroll, S. A., Torrents, D., Knowler, W. C., Baier, L. J., Burtt, N., González-Villalpando, C., Haiman, C. A., Aguilar-Salinas, C. A., Tusié-Luna, T., Flannick, J., Jacobs, S. B. R., Orozco, L., Altshuler, D. & Florez, J. C., Nov 2017, In: Diabetes. 66, 11, p. 2903-2914 12 p.

    Research output: Contribution to journalArticlepeer-review

    22 Scopus citations
  • A low-frequency inactivating AKT2 variant enriched in the finnish population is associated with fasting insulin levels and type 2 diabetes risk

    Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B. R., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., Depristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., de Angelis, M. H., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Hale, D. E., Fowler, S. P., Arya, R., Defronzo, R. A., Abboud, H. E., Syvänen, A. C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S. T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J. Y., Han, B. G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., E Mel Ander, O. L., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., U, J. L., Khor, C. C., Chia, K. S., Lim, W. Y., Cheng, C. Y., Chan, E., Shyong Tai, E., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Na Kravi C, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Kat, K. H., Farmer, A. J., Frayling, T. M., O’rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stan?cáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Antero Kesaniemi, Y., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., Jul 1 2017, In: Diabetes. 66, 7, p. 2019-2032 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls

    Flannick, J., Fuchsberger, C., Mahajan, A., Teslovich, T. M., Agarwala, V., Gaulton, K. J., Caulkins, L., Koesterer, R., Ma, C., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F. & 281 others, Highland, H. M., Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., Van De Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njølstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jørgensen, M. E., Jørgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., De Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P. M., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Scott, L. J., Morris, A. P., Kang, H. M., Altshuler, D., Burtt, N. P., Florez, J. C., Boehnke, M. & McCarthy, M. I., Dec 19 2017, In: Scientific Data. 4, 170179.

    Research output: Contribution to journalArticlepeer-review

    13 Scopus citations
  • Novel genetic loci associated with hippocampal volume

    Hibar, D. P., Adams, H. H. H., Jahanshad, N., Chauhan, G., Stein, J. L., Hofer, E., Renteria, M. E., Bis, J. C., Arias-Vasquez, A., Ikram, M. K., Desrivières, S., Vernooij, M. W., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S., Armstrong, N. J., Athanasiu, L. & 312 others, Axelsson, T., Beecham, A. H., Beiser, A., Bernard, M., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chen, Q., Ching, C. R. K., Chouraki, V., Cuellar-Partida, G., Crivello, F., Den Braber, A., Doan, N. T., Ehrlich, S., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Grimm, O., Griswold, M. E., Guadalupe, T., Gutman, B. A., Hass, J., Haukvik, U. K., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Jørgensen, K. N., Karbalai, N., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liewald, D. C. M., Lopez, L. M., Luciano, M., MacAre, C., Marquand, A. F., Matarin, M., Mather, K. A., Mattheisen, M., McKay, D. R., Milaneschi, Y., Muñoz Maniega, S., Nho, K., Nugent, A. C., Nyquist, P., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pirpamer, L., Pütz, B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Ropele, S., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Saremi, A., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Trompet, S., Vaidya, D., Van Der Grond, J., Van Der Lee, S. J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Wittfeld, K., Woldehawariat, G., Wolf, C., Wolfers, T., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Craen, A. J. M., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Deary, I. J., Debette, S., Decarli, C., Delanty, N., Depondt, C., Destefano, A., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Enzinger, C., Erk, S., Espeseth, T., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Fornage, M., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Håberg, A. K., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Huentelman, M., Pol, H. E. H., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, F. J., McMahon, K. L., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schmidt, H., Schofield, P. R., Sigursson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Tsolaki, M., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Haren, N. E. M., Van 'T Ent, D., Van Tol, M. J., Vardarajan, B. N., Vellas, B., Veltman, D. J., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, R. H., Zonderman, A. B., Martin, N. G., Van Duijn, C. M., Wright, M. J., Longstreth, W. T., Schumann, G., Grabe, H. J., Franke, B., Launer, L. J., Medland, S. E., Seshadri, S., Thompson, P. M. & Ikram, M. A., Jan 18 2017, In: Nature communications. 8, 13624.

    Research output: Contribution to journalArticlepeer-review

    121 Scopus citations
  • The genetic basis of the comorbidity between cannabis use and major depression

    Hodgson, K., Almasy, L. A., Knowles, E. E. M., Kent, J. W., Curran, J. E., Dyer, T. D., Goring, H. HH., Olvera, R. L., Woolsey, M. D., Duggirala, R., Fox, P. T., Blangero, J. C. & Glahn, D. C., Jan 1 2017, In: Addiction. 112, 1, p. 113-123 11 p.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • 2016

    Analysis of protein-coding genetic variation in 60,706 humans

    Lek, M., Karczewski, K. J., Minikel, E. V., Samocha, K. E., Banks, E., Fennell, T., O'Donnell-Luria, A. H., Ware, J. S., Hill, A. J., Cummings, B. B., Tukiainen, T., Birnbaum, D. P., Kosmicki, J. A., Duncan, L. E., Estrada, K., Zhao, F., Zou, J., Pierce-Hoffman, E., Berghout, J., Cooper, D. N. & 153 others, Deflaux, N., DePristo, M., Do, R., Flannick, J., Fromer, M., Gauthier, L., Goldstein, J., Gupta, N., Howrigan, D., Kiezun, A., Kurki, M. I., Moonshine, A. L., Natarajan, P., Orozco, L., Peloso, G. M., Poplin, R., Rivas, M. A., Ruano-Rubio, V., Rose, S. A., Ruderfer, D. M., Shakir, K., Stenson, P. D., Stevens, C., Thomas, B. P., Tiao, G., Tusie-Luna, M. T., Weisburd, B., Won, H. H., Yu, D., Altshuler, D. M., Ardissino, D., Boehnke, M., Danesh, J., Donnelly, S., Elosua, R., Florez, J. C., Gabriel, S. B., Getz, G., Glatt, S. J., Hultman, C. M., Kathiresan, S., Laakso, M., McCarroll, S., McCarthy, M. I., McGovern, D., McPherson, R., Neale, B. M., Palotie, A., Purcell, S. M., Saleheen, D., Scharf, J. M., Sklar, P., Sullivan, P. F., Tuomilehto, J., Tsuang, M. T., Watkins, H. C., Wilson, J. G., Daly, M. J., MacArthur, D. G., Abboud, H. E., Abecasis, G., Aguilar-Salinas, C. A., Arellano-Campos, O., Atzmon, G., Aukrust, I., Barr, C. L., Bell, G. I., Bergen, S., Bjørkhaug, L., Blangero, J., Bowden, D. W., Budman, C. L., Burtt, N. P., Centeno-Cruz, F., Chambers, J. C., Chambert, K., Clarke, R., Collins, R., Coppola, G., Córdova, E. J., Cortes, M. L., Cox, N. J., Duggirala, R., Farrall, M., Fernandez-Lopez, J. C., Fontanillas, P., Frayling, T. M., Freimer, N. B., Fuchsberger, C., García-Ortiz, H., Goel, A., Gómez-Vázquez, M. J., González-Villalpando, M. E., González-Villalpando, C., Grados, M. A., Groop, L., Haiman, C. A., Hanis, C. L., Hattersley, A. T., Henderson, B. E., Hopewell, J. C., Huerta-Chagoya, A., Islas-Andrade, S., Jacobs, S. B., Jalilzadeh, S., Jenkinson, C. P., Moran, J., Jiménez-Morale, S., Kähler, A., King, R. A., Kirov, G., Kooner, J. S., Kyriakou, T., Lee, J. Y., Lehman, D. M., Lyon, G., MacMahon, W., Magnusson, P. K., Mahajan, A., Marrugat, J., Martínez-Hernández, A., Mathews, C. A., McVean, G., Meigs, J. B., Meitinger, T., Mendoza-Caamal, E., Mercader, J. M., Mohlke, K. L., Moreno-Macías, H., Morris, A. P., Najmi, L. A., Njølstad, P. R., O'Donovan, M. C., Ordóñez-Sánchez, M. L., Owen, M. J., Park, T., Pauls, D. L., Posthuma, D., Revilla-Monsalve, C., Riba, L., Ripke, S., Rodríguez-Guillén, R., Rodríguez-Torres, M., Sandor, P., Seielstad, M., Sladek, R., Soberón, X., Spector, T. D., Tai, S. E., Teslovich, T. M., Walford, G., Wilkens, L. R. & Williams, A. L., Aug 17 2016, In: Nature. 536, 7616, p. 285-291 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5466 Scopus citations
  • Genetic influences on schizophrenia and subcortical brain volumes: Large-scale proof of concept

    Psychosis Endophenotypes International Consortium, Feb 23 2016, In: Nature Neuroscience. 19, 3, p. 420-431 12 p.

    Research output: Contribution to journalArticlepeer-review

    127 Scopus citations
  • Genome-wide linkage on chromosome 10q26 for a dimensional scale of major depression

    Knowles, E. E. M., Kent, J. W., McKay, D. R., Sprooten, E., Mathias, S. R., Curran, J. E., Carless, M. A., De Almeida, M. A. A., Goring, H. HH., Dyer, T. D., Olvera, R. L., Fox, P. T., Duggirala, R., Almasy, L. A., Blangero, J. C. & Glahn, D. C., Feb 1 2016, In: Journal of Affective Disorders. 191, p. 123-131 9 p.

    Research output: Contribution to journalArticlepeer-review

    13 Scopus citations
  • Novel genetic loci underlying human intracranial volume identified through genome-wide association

    Adams, H. H. H., Hibar, D. P., Chouraki, V., Stein, J. L., Nyquist, P. A., Rentería, M. E., Trompet, S., Arias-Vasquez, A., Seshadri, S., Desrivières, S., Beecham, A. H., Jahanshad, N., Wittfeld, K., Van Der Lee, S. J., Abramovic, L., Alhusaini, S., Amin, N., Andersson, M., Arfanakis, K., Aribisala, B. S. & 322 others, Armstrong, N. J., Athanasiu, L., Axelsson, T., Beiser, A., Bernard, M., Bis, J. C., Blanken, L. M. E., Blanton, S. H., Bohlken, M. M., Boks, M. P., Bralten, J., Brickman, A. M., Carmichael, O., Chakravarty, M. M., Chauhan, G., Chen, Q., Ching, C. R. K., Cuellar-Partida, G., Braber, A. D., Doan, N. T., Ehrlich, S., Filippi, I., Ge, T., Giddaluru, S., Goldman, A. L., Gottesman, R. F., Greven, C. U., Grimm, O., Griswold, M. E., Guadalupe, T., Hass, J., Haukvik, U. K., Hilal, S., Hofer, E., Hoehn, D., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kasperaviciute, D., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Liao, J., Liewald, D. C. M., Lopez, L. M., Luciano, M., Macare, C., Marquand, A., Matarin, M., Mather, K. A., Mattheisen, M., Mazoyer, B., McKay, D. R., McWhirter, R., Milaneschi, Y., Mirza-Schreiber, N., Muetzel, R. L., Maniega, S. M., Nho, K., Nugent, A. C., Loohuis, L. M. O., Oosterlaan, J., Papmeyer, M., Pappa, I., Pirpamer, L., Pudas, S., Pütz, B., Rajan, K. B., Ramasamy, A., Richards, J. S., Risacher, S. L., Roiz-Santiañez, R., Rommelse, N., Rose, E. J., Royle, N. A., Rundek, T., Sämann, P. G., Satizabal, C. L., Schmaal, L., Schork, A. J., Shen, L., Shin, J., Shumskaya, E., Smith, A. V., Sprooten, E., Strike, L. T., Teumer, A., Thomson, R., Tordesillas-Gutierrez, D., Toro, R., Trabzuni, D., Vaidya, D., Van Der Grond, J., Van Der Meer, D., Van Donkelaar, M. M. J., Van Eijk, K. R., Van Erp, T. G. M., Van Rooij, D., Walton, E., Westlye, L. T., Whelan, C. D., Windham, B. G., Winkler, A. M., Woldehawariat, G., Wolf, C., Wolfers, T., Xu, B., Yanek, L. R., Yang, J., Zijdenbos, A., Zwiers, M. P., Agartz, I., Aggarwal, N. T., Almasy, L., Ames, D., Amouyel, P., Andreassen, O. A., Arepalli, S., Assareh, A. A., Barral, S., Bastin, M. E., Becker, D. M., Becker, J. T., Bennett, D. A., Blangero, J., Van Bokhoven, H., Boomsma, D. I., Brodaty, H., Brouwer, R. M., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Bulayeva, K. B., Cahn, W., Calhoun, V. D., Cannon, D. M., Cavalleri, G. L., Chen, C., Cheng, C. Y., Cichon, S., Cookson, M. R., Corvin, A., Crespo-Facorro, B., Curran, J. E., Czisch, M., Dale, A. M., Davies, G. E., De Geus, E. J. C., De Jager, P. L., De Zubicaray, G. I., Delanty, N., Depondt, C., Destefano, A. L., Dillman, A., Djurovic, S., Donohoe, G., Drevets, W. C., Duggirala, R., Dyer, T. D., Erk, S., Espeseth, T., Evans, D. A., Fedko, I. O., Fernández, G., Ferrucci, L., Fisher, S. E., Fleischman, D. A., Ford, I., Foroud, T. M., Fox, P. T., Francks, C., Fukunaga, M., Gibbs, J. R., Glahn, D. C., Gollub, R. L., Göring, H. H. H., Grabe, H. J., Green, R. C., Gruber, O., Gudnason, V., Guelfi, S., Hansell, N. K., Hardy, J., Hartman, C. A., Hashimoto, R., Hegenscheid, K., Heinz, A., Le Hellard, S., Hernandez, D. G., Heslenfeld, D. J., Ho, B. C., Hoekstra, P. J., Hoffmann, W., Hofman, A., Holsboer, F., Homuth, G., Hosten, N., Hottenga, J. J., Pol, H. E. H., Ikeda, M., Ikram, M. K., Jack, C. R., Jenkinson, M., Johnson, R., Jönsson, E. G., Jukema, J. W., Kahn, R. S., Kanai, R., Kloszewska, I., Knopman, D. S., Kochunov, P., Kwok, J. B., Lawrie, S. M., Lemaître, H., Liu, X., Longo, D. L., Longstreth, W. T., Lopez, O. L., Lovestone, S., Martinez, O., Martinot, J. L., Mattay, V. S., McDonald, C., McIntosh, A. M., McMahon, K. L., McMahon, F. J., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Mohnke, S., Montgomery, G. W., Morris, D. W., Mosley, T. H., Mühleisen, T. W., Müller-Myhsok, B., Nalls, M. A., Nauck, M., Nichols, T. E., Niessen, W. J., Nöthen, M. M., Nyberg, L., Ohi, K., Olvera, R. L., Ophoff, R. A., Pandolfo, M., Paus, T., Pausova, Z., Penninx, B. W. J. H., Pike, G. B., Potkin, S. G., Psaty, B. M., Reppermund, S., Rietschel, M., Roffman, J. L., Romanczuk-Seiferth, N., Rotter, J. I., Ryten, M., Sacco, R. L., Sachdev, P. S., Saykin, A. J., Schmidt, R., Schofield, P. R., Sigurdsson, S., Simmons, A., Singleton, A., Sisodiya, S. M., Smith, C., Smoller, J. W., Soininen, H., Srikanth, V., Steen, V. M., Stott, D. J., Sussmann, J. E., Thalamuthu, A., Tiemeier, H., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Tzourio, C., Uitterlinden, A. G., Hernández, M. C. V., Van Der Brug, M., Van Der Lugt, A., Van Der Wee, N. J. A., Van Duijn, C. M., Van Haren, N. E. M., Van't Ent, D., Van Tol, M. J., Vardarajan, B. N., Veltman, D. J., Vernooij, M. W., Völzke, H., Walter, H., Wardlaw, J. M., Wassink, T. H., Weale, M. E., Weinberger, D. R., Weiner, M. W., Wen, W., Westman, E., White, T., Wong, T. Y., Wright, C. B., Zielke, H. R., Zonderman, A. B., Deary, I. J., Decarli, C., Schmidt, H., Martin, N. G., De Craen, A. J. M., Wright, M. J., Launer, L. J., Schumann, G., Fornage, M., Franke, B., Debette, S., Medland, S. E., Ikram, M. A. & Thompson, P. M., Dec 1 2016, In: Nature Neuroscience. 19, 12, p. 1569-1582 14 p.

    Research output: Contribution to journalArticlepeer-review

    112 Scopus citations
  • Physical activity and FTO genotype by physical activity interactive influences on obesity

    Kim, J. Y., DeMenna, J. T., Puppala, S., Chittoor, G., Schneider, J., Duggirala, R., Mandarino, L. J., Shaibi, G. Q. & Coletta, D. K., Feb 24 2016, In: BMC genetics. 17, 1, 47.

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations
  • Recurrent major depression and right hippocampal volume: A bivariate linkage and association study

    Mathias, S. R., Knowles, E. E. M., Kent, J. W., Mckay, D. R., Curran, J. E., de Almeida, M. A. A., Dyer, T. D., Goring, H. HH., Olvera, R. L., Duggirala, R., Fox, P. T., Almasy, L. A., Blangero, J. C. & Glahn, D. C., Jan 1 2016, In: Human Brain Mapping. 37, 1, p. 191-202 12 p.

    Research output: Contribution to journalArticlepeer-review

    15 Scopus citations
  • Selecting SNPs informative for African, American Indian and European Ancestry: Application to the Family Investigation of Nephropathy and Diabetes (FIND)

    Williams, R. C., Elston, R. C., Kumar, P., Knowler, W. C., Abboud, H. E., Adler, S., Bowden, D. W., Divers, J., Freedman, B. I., Igo, R. P., Ipp, E., Iyengar, S. K., Kimmel, P. L., Klag, M. J., Kohn, O., Langefeld, C. D., Leehey, D. J., Nelson, R. G., Nicholas, S. B., Pahl, M. V. & 108 others, Parekh, R. S., Rotter, J. I., Schelling, J. R., Sedor, J. R., Shah, V. O., Smith, M. W., Taylor, K. D., Thameem, F., Thornley-Brown, D., Winkler, C. A., Guo, X., Zager, P., Hanson, R. L., FIND Research Group, R. G., S.K. Iyengar, I., Elston, R. C., Goddard, K. A. B., Olson, J. M., Ialacci, S., Fondran, J., Horvath, A., Igo, R., Jun, G., Kramp, K., Molineros, J., Quade, S. R. E., Schelling, J., Pickens, A., Humbert, L., Getz-Fradley, L., Adler, S., Ipp, E., Pahl, M., Seldin, M. F., Snyder, S., Tayek, J., Hernandez, E., LaPage, J., Garcia, C., Gonzalez, J., Aguilar, M., Weparekhgr, R. W., Kao, L., Meoni, L., Whitehead, T., Chester, J., Knowler, W. C., Hanson, R. L., Nelson, R. G., Wolford, J., Jones, L., Juan, R., Lovelace, R., Luethe, C., Phillips, L. M., Sewemaenewa, J., Sili, I., Waseta, B., Saad, M. F., Nicholas, S. B., Chen, Y. D. I., Guo, X., Rotter, J., Taylor, K., Budgett, M., Hariri, F., Zager, P., Shah, V., Scavini, M., Bobelu, A., Abboud, H., Arar, N., Duggirala, R., Kasinath, B. S., Thameem, F., Stern, M., Freedman, B. I., Bowden, D. W., Langefeld, C. D., Satko, S. C., Rich, S. S., Warren, S., Viverette, S., Brooks, G., Young, R., Spainhour, M., Winkler, C., Smith, M. W., Thompson, M., Hanson, R., Kessing, B., Leehey, D. J., Barone, G., Thornley-Brown, D., Jefferson, C., Kohn, O. F., Brown, C. S., Briggs, J. P., Kimmel, P. L., Rasooly, R., D. Warnock, W., Cardon, L., Chakraborty, R., Dunston, G. M., Hostetter, T., O'Brien, S. J., Rioux, J. & Spielman, R., May 4 2016, In: BMC genomics. 17, 1, 325.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • The genetic architecture of type 2 diabetes

    Fuchsberger, C., Flannick, J., Teslovich, T. M., Mahajan, A., Agarwala, V., Gaulton, K. J., Ma, C., Fontanillas, P., Moutsianas, L., McCarthy, D. J., Rivas, M. A., Perry, J. R. B., Sim, X., Blackwell, T. W., Robertson, N. R., Rayner, N. W., Cingolani, P., Locke, A. E., Tajes, J. F., Highland, H. M. & 281 others, Dupuis, J., Chines, P. S., Lindgren, C. M., Hartl, C., Jackson, A. U., Chen, H., Huyghe, J. R., Van De Bunt, M., Pearson, R. D., Kumar, A., Müller-Nurasyid, M., Grarup, N., Stringham, H. M., Gamazon, E. R., Lee, J., Chen, Y., Scott, R. A., Below, J. E., Chen, P., Huang, J., Go, M. J., Stitzel, M. L., Pasko, D., Parker, S. C. J., Varga, T. V., Green, T., Beer, N. L., Day-Williams, A. G., Ferreira, T., Fingerlin, T., Horikoshi, M., Hu, C., Huh, I., Ikram, M. K., Kim, B. J., Kim, Y., Kim, Y. J., Kwon, M. S., Lee, J., Lee, S., Lin, K. H., Maxwell, T. J., Nagai, Y., Wang, X., Welch, R. P., Yoon, J., Zhang, W., Barzilai, N., Voight, B. F., Han, B. G., Jenkinson, C. P., Kuulasmaa, T., Kuusisto, J., Manning, A., Ng, M. C. Y., Palmer, N. D., Balkau, B., Stančáková, A., Abboud, H. E., Boeing, H., Giedraitis, V., Prabhakaran, D., Gottesman, O., Scott, J., Carey, J., Kwan, P., Grant, G., Smith, J. D., Neale, B. M., Purcell, S., Butterworth, A. S., Howson, J. M. M., Lee, H. M., Lu, Y., Kwak, S. H., Zhao, W., Danesh, J., Lam, V. K. L., Park, K. S., Saleheen, D., So, W. Y., Tam, C. H. T., Afzal, U., Aguilar, D., Arya, R., Aung, T., Chan, E., Navarro, C., Cheng, C. Y., Palli, D., Correa, A., Curran, J. E., Rybin, D., Farook, V. S., Fowler, S. P., Freedman, B. I., Griswold, M., Hale, D. E., Hicks, P. J., Khor, C. C., Kumar, S., Lehne, B., Thuillier, D., Lim, W. Y., Liu, J., Van Der Schouw, Y. T., Loh, M., Musani, S. K., Puppala, S., Scott, W. R., Yengo, L., Tan, S. T., Taylor, H. A., Thameem, F., Wilson, G., Wong, T. Y., Njolstad, P. R., Levy, J. C., Mangino, M., Bonnycastle, L. L., Schwarzmayr, T., Fadista, J., Surdulescu, G. L., Herder, C., Groves, C. J., Wieland, T., Bork-Jensen, J., Brandslund, I., Christensen, C., Koistinen, H. A., Doney, A. S. F., Kinnunen, L., Esko, T., Farmer, A. J., Hakaste, L., Hodgkiss, D., Kravic, J., Lyssenko, V., Hollensted, M., Jorgensen, M. E., Jorgensen, T., Ladenvall, C., Justesen, J. M., Käräjämäki, A., Kriebel, J., Rathmann, W., Lannfelt, L., Lauritzen, T., Narisu, N., Linneberg, A., Melander, O., Milani, L., Neville, M., Orho-Melander, M., Qi, L., Qi, Q., Roden, M., Rolandsson, O., Swift, A., Rosengren, A. H., Stirrups, K., Wood, A. R., Mihailov, E., Blancher, C., Carneiro, M. O., Maguire, J., Poplin, R., Shakir, K., Fennell, T., DePristo, M., De Angelis, M. H., Deloukas, P., Gjesing, A. P., Jun, G., Nilsson, P., Murphy, J., Onofrio, R., Thorand, B., Hansen, T., Meisinger, C., Hu, F. B., Isomaa, B., Karpe, F., Liang, L., Peters, A., Huth, C., O'Rahilly, S. P., Palmer, C. N. A., Pedersen, O., Rauramaa, R., Tuomilehto, J., Salomaa, V., Watanabe, R. M., Syvänen, A. C., Bergman, R. N., Bharadwaj, D., Bottinger, E. P., Cho, Y. S., Chandak, G. R., Chan, J. C. N., Chia, K. S., Daly, M. J., Ebrahim, S. B., Langenberg, C., Elliott, P., Jablonski, K. A., Lehman, D. M., Jia, W., Ma, R. C. W., Pollin, T. I., Sandhu, M., Tandon, N., Froguel, P., Barroso, I., Teo, Y. Y., Zeggini, E., Loos, R. J. F., Small, K. S., Ried, J. S., DeFronzo, R. A., Grallert, H., Glaser, B., Metspalu, A., Wareham, N. J., Walker, M., Banks, E., Gieger, C., Ingelsson, E., Im, H. K., Illig, T., Franks, P. W., Buck, G., Trakalo, J., Buck, D., Prokopenko, I., Mägi, R., Lind, L., Farjoun, Y., Owen, K. R., Gloyn, A. L., Strauch, K., Tuomi, T., Kooner, J. S., Lee, J. Y., Park, T., Donnelly, P., Morris, A. D., Hattersley, A. T., Bowden, D. W., Collins, F. S., Atzmon, G., Chambers, J. C., Spector, T. D., Laakso, M., Strom, T. M., Bell, G. I., Blangero, J., Duggirala, R., Tai, E. S., McVean, G., Hanis, C. L., Wilson, J. G., Seielstad, M., Frayling, T. M., Meigs, J. B., Cox, N. J., Sladek, R., Lander, E. S., Gabriel, S., Burtt, N. P., Mohlke, K. L., Meitinger, T., Groop, L., Abecasis, G., Florez, J. C., Scott, L. J., Morris, A. P., Kang, H. M., Boehnke, M., Altshuler, D. & McCarthy, M. I., Jul 11 2016, In: Nature. 536, 7614, p. 41-47 7 p.

    Research output: Contribution to journalArticlepeer-review

    555 Scopus citations
  • Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms

    T2D-GENES Consortium, May 15 2016, In: Human molecular genetics. 25, 10, p. 2070-2081 12 p.

    Research output: Contribution to journalArticlepeer-review

    15 Scopus citations
  • Transcriptomics in type 2 diabetes: Bridging the gap between genotype and phenotype

    Jenkinson, C. P., Göring, H. H. H., Arya, R., Blangero, J., Duggirala, R. & DeFronzo, R. A., Jun 1 2016, In: Genomics Data. 8, p. 25-36 12 p.

    Research output: Contribution to journalArticlepeer-review

    17 Scopus citations
  • 2015

    A new strategy for enhancing imputation quality of rare variants from next-generation sequencing data via combining SNP and exome chip data

    T2D-Genes Consortium and Taesung Park, Dec 29 2015, In: BMC genomics. 16, 1, 1109.

    Research output: Contribution to journalArticlepeer-review

    6 Scopus citations
  • Common genetic variants influence human subcortical brain structures

    Hibar, D. P., Stein, J. L., Renteria, M. E., Arias-Vasquez, A., Desrivières, S., Jahanshad, N., Toro, R., Wittfeld, K., Abramovic, L., Andersson, M., Aribisala, B. S., Armstrong, N. J., Bernard, M., Bohlken, M. M., Boks, M. P., Bralten, J., Brown, A. A., Mallar Chakravarty, M., Chen, Q., Ching, C. R. K. & 267 others, Cuellar-Partida, G., Den Braber, A., Giddaluru, S., Goldman, A. L., Grimm, O., Guadalupe, T., Hass, J., Woldehawariat, G., Holmes, A. J., Hoogman, M., Janowitz, D., Jia, T., Kim, S., Klein, M., Kraemer, B., Lee, P. H., Olde Loohuis, L. M., Luciano, M., MacAre, C., Mather, K. A., Mattheisen, M., Milaneschi, Y., Nho, K., Papmeyer, M., Ramasamy, A., Risacher, S. L., Roiz-Santiañez, R., Rose, E. J., Salami, A., Sämann, P. G., Schmaal, L., Schork, A. J., Shin, J., Strike, L. T., Teumer, A., Van Donkelaar, M. M. J., Van Eijk, K. R., Walters, R. K., Westlye, L. T., Whelan, C. D., Winkler, A. M., Zwiers, M. P., Alhusaini, S., Athanasiu, L., Ehrlich, S., Hakobjan, M. M. H., Hartberg, C. B., Haukvik, U. K., Heister, A. J. G. A. M., Hoehn, D., Kasperaviciute, D., Liewald, D. C. M., Lopez, L. M., Makkinje, R. R. R., Matarin, M., Naber, M. A. M., Reese McKay, D., Needham, M., Nugent, A. C., Pütz, B., Royle, N. A., Shen, L., Sprooten, E., Trabzuni, D., Van Der Marel, S. S. L., Van Hulzen, K. J. E., Walton, E., Wolf, C., Almasy, L., Ames, D., Arepalli, S., Assareh, A. A., Bastin, M. E., Brodaty, H., Bulayeva, K. B., Carless, M. A., Cichon, S., Corvin, A., Curran, J. E., Czisch, M., De Zubicaray, G. I., Dillman, A., Duggirala, R., Dyer, T. D., Erk, S., Fedko, I. O., Ferrucci, L., Foroud, T. M., Fox, P. T., Fukunaga, M., Raphael Gibbs, J., Göring, H. H. H., Green, R. C., Guelfi, S., Hansell, N. K., Hartman, C. A., Hegenscheid, K., Heinz, A., Hernandez, D. G., Heslenfeld, D. J., Hoekstra, P. J., Holsboer, F., Homuth, G., Hottenga, J. J., Ikeda, M., Jack, C. R., Jenkinson, M., Johnson, R., Kanai, R., Keil, M., Kent, J. W., Kochunov, P., Kwok, J. B., Lawrie, S. M., Liu, X., Longo, D. L., McMahon, K. L., Meisenzahl, E., Melle, I., Mohnke, S., Montgomery, G. W., Mostert, J. C., Mühleisen, T. W., Nalls, M. A., Nichols, T. E., Nilsson, L. G., Nöthen, M. M., Ohi, K., Olvera, R. L., Perez-Iglesias, R., Bruce Pike, G., Potkin, S. G., Reinvang, I., Reppermund, S., Rietschel, M., Romanczuk-Seiferth, N., Rosen, G. D., Rujescu, D., Schnell, K., Schofield, P. R., Smith, C., Steen, V. M., Sussmann, J. E., Thalamuthu, A., Toga, A. W., Traynor, B. J., Troncoso, J., Turner, J. A., Valdés Hernández, M. C., Van 'T Ent, D., Van Der Brug, M., Van Der Wee, N. J. A., Van Tol, M. J., Veltman, D. J., Wassink, T. H., Westman, E., Zielke, R. H., Zonderman, A. B., Ashbrook, D. G., Hager, R., Lu, L., McMahon, F. J., Morris, D. W., Williams, R. W., Brunner, H. G., Buckner, R. L., Buitelaar, J. K., Cahn, W., Calhoun, V. D., Cavalleri, G. L., Crespo-Facorro, B., Dale, A. M., Davies, G. E., Delanty, N., Depondt, C., Djurovic, S., Drevets, W. C., Espeseth, T., Gollub, R. L., Ho, B. C., Hoffmann, W., Hosten, N., Kahn, R. S., Le Hellard, S., Meyer-Lindenberg, A., Müller-Myhsok, B., Nauck, M., Nyberg, L., Pandolfo, M., Penninx, B. W. J. H., Roffman, J. L., Sisodiya, S. M., Smoller, J. W., Van Bokhoven, H., Van Haren, N. E. M., Völzke, H., Walter, H., Weiner, M. W., Wen, W., White, T., Agartz, I., Andreassen, O. A., Blangero, J., Boomsma, D. I., Brouwer, R. M., Cannon, D. M., Cookson, M. R., De Geus, E. J. C., Deary, I. J., Donohoe, G., Fernández, G., Fisher, S. E., Francks, C., Glahn, D. C., Grabe, H. J., Gruber, O., Hardy, J., Hashimoto, R., Hulshoff Pol, H. E., Jönsson, E. G., Kloszewska, I., Lovestone, S., Mattay, V. S., Mecocci, P., McDonald, C., McIntosh, A. M., Ophoff, R. A., Paus, T., Pausova, Z., Ryten, M., Sachdev, P. S., Saykin, A. J., Simmons, A., Singleton, A., Soininen, H., Wardlaw, J. M., Weale, M. E., Weinberger, D. R., Adams, H. H. H., Launer, L. J., Seiler, S., Schmidt, R., Chauhan, G., Satizabal, C. L., Becker, J. T., Yanek, L., Van Der Lee, S. J., Ebling, M., Fischl, B., Longstreth, W. T., Greve, D., Schmidt, H., Nyquist, P., Vinke, L. N., Van Duijn, C. M., Xue, L., Mazoyer, B., Bis, J. C., Gudnason, V., Seshadri, S., Ikram, M. A., Martin, N. G., Wright, M. J., Schumann, G., Franke, B., Thompson, P. M. & Medland, S. E., Apr 9 2015, In: Nature. 520, 7546, p. 224-229 6 p.

    Research output: Contribution to journalArticlepeer-review

    461 Scopus citations
  • Genome mapping and genomics in human and non-human primates

    Duggirala, R., Almasy, L., Williams-Blangero, S., Paul, S. F. D. & Kole, C., Jan 1 2015, Springer Berlin Heidelberg. 305 p.

    Research output: Book/ReportBook

    1 Scopus citations
  • Genome-Wide Association and Trans-ethnic Meta-Analysis for Advanced Diabetic Kidney Disease: Family Investigation of Nephropathy and Diabetes (FIND)

    Iyengar, S. K., Sedor, J. R., Freedman, B. I., Kao, W. H. L., Kretzler, M., Keller, B. J., Abboud, H. E., Adler, S. G., Best, L. G., Bowden, D. W., Burlock, A., Chen, Y. D. I., Cole, S. A., Comeau, M. E., Curtis, J. M., Divers, J., Drechsler, C., Duggirala, R., Elston, R. C., Guo, X. & 39 others, Huang, H., Hoffmann, M. M., Howard, B. V., Ipp, E., Kimmel, P. L., Klag, M. J., Knowler, W. C., Kohn, O. F., Leak, T. S., Leehey, D. J., Li, M., Malhotra, A., März, W., Nair, V., Nelson, R. G., Nicholas, S. B., O’Brien, S. J., Pahl, M. V., Parekh, R. S., Pezzolesi, M. G., Rasooly, R. S., Rotimi, C. N., Rotter, J. I., Schelling, J. R., Seldin, M. F., Shah, V. O., Smiles, A. M., Smith, M. W., Taylor, K. D., Thameem, F., Thornley-Brown, D. P., Truitt, B. J., Wanner, C., Weil, E. J., Winkler, C. A., Zager, P. G., Igo, R. P., Hanson, R. L. & Langefeld, C. D., Aug 1 2015, In: PLoS Genetics. 11, 8, e1005352.

    Research output: Contribution to journalArticlepeer-review

    68 Scopus citations
  • Mapping of susceptibility genes for obesity, type 2 diabetes, and the metabolic syndrome in human populations

    Arya, R., Puppala, S., Farook, V. S., Chittoor, G., Jenkinson, C. P., Blangero, J., Hale, D. E., Duggirala, R. & Almasy, L., Jan 1 2015, Genome Mapping and Genomics in Human and Non-Human Primates. Springer Berlin Heidelberg, p. 181-245 65 p.

    Research output: Chapter in Book/Report/Conference proceedingChapter

    4 Scopus citations
  • Pleiotropic locus for emotion recognition and amygdala volume identified using univariate and bivariate linkage

    Knowles, E. E. M., McKay, R., Kent, J. W., Sprooten, E., Carless, M. A., Curran, J. E., De Almeida, M. A. A., Dyer, T. D., Goring, H. HH., Olvera, R. L., Duggirala, R., Fox, P. T., Almasy, L. A., Blangero, J. C. & Glahn, D. C., Feb 1 2015, In: American Journal of Psychiatry. 172, 2, p. 190-199 10 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Preface

    Duggirala, R., Almasy, L., Williams-Blangero, S., Paul, S. F. D. & Kole, C., Jan 1 2015, Genome Mapping and Genomics in Human and Non-Human Primates. Springer Berlin Heidelberg, p. v-vi

    Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

  • Shared genetic variance between obesity and white matter integrity in Mexican Americans

    Spieker, E. A., Kochunov, P., Rowland, L. M., Sprooten, E., Winkler, A. M., Olvera, R. L., Almasy, L., Duggirala, R., Fox, P. T., Blangero, J., Glahn, D. C. & Curran, J. E., 2015, In: Frontiers in Genetics. 5, FEB, 00026.

    Research output: Contribution to journalArticlepeer-review

    11 Scopus citations
  • 2014

    Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

    The MAGIC investigators & The GIANT consortium, Aug 7 2014, In: PLoS Genetics. 10, 8, e1004517.

    Research output: Contribution to journalArticlepeer-review

    123 Scopus citations
  • 2012

    High dimensional endophenotype ranking in the search for major depression risk genes

    Glahn, D. C., Curran, J. E., Winkler, A. M., Carless, M. A., Kent, J. W., Charlesworth, J. C., Johnson, M. P., Goring, H. HH., Cole, S. A., Dyer, T. D., Moses, E. K., Olvera, R. L., Kochunov, P., Duggirala, R., Fox, P. T., Almasy, L. A. & Blangero, J. C., Jan 1 2012, In: Biological Psychiatry. 71, 1, p. 6-14 9 p.

    Research output: Contribution to journalArticlepeer-review

    135 Scopus citations
  • 2011

    Blood pressure and cerebral white matter share common genetic factors in Mexican Americans

    Kochunov, P., Glahn, D. C., Lancaster, J., Winkler, A., Karlsgodt, K., Olvera, R. L., Curran, J. E., Carless, M. A., Dyer, T. D., Almasy, L., Duggirala, R., Fox, P. T. & Blangero, J., Feb 2011, In: Hypertension. 57, 2, p. 330-335 6 p.

    Research output: Contribution to journalArticlepeer-review

    29 Scopus citations
  • Genetic factors influence serological measures of common infections

    Rubicz, R., Leach, C. T., Kraig, E., Dhurandhar, N. V., Duggirala, R., Blangero, J. C., Yolken, R. & Goring, H. HH., Oct 2011, In: Human Heredity. 72, 2, p. 133-141 9 p.

    Research output: Contribution to journalArticlepeer-review

    19 Scopus citations
  • Genomewide linkage scan for diabetic renal failure and albuminuria: The find study

    Igo, R. P., Iyengar, S. K., Nicholas, S. B., Goddard, K. A. B., Langefeld, C. D., Hanson, R. L., Duggirala, R., Divers, J., Abboud, H., Adler, S. G., Arar, N. H., Horvath, A., Elston, R. C., Bowden, D. W., Guo, X., Ipp, E., Kao, W. H. L., Kimmel, P. L., Knowler, W. C., Meoni, L. A. & 12 others, Molineros, J., Nelson, R. G., Pahl, M. V., Parekh, R. S., Rasooly, R. S., Schelling, J. R., Shah, V. O., Smith, M. W., Winkler, C. A., Zager, P. G., Sedor, J. R. & Freedman, B. I., May 2011, In: American journal of nephrology. 33, 5, p. 381-389 9 p.

    Research output: Contribution to journalArticlepeer-review

    43 Scopus citations
  • 2010

    A multimodal assessment of the genetic control over working memory

    Karlsgodt, K. H., Kochunov, P., Winkler, A. M., Laird, A. R., Almasy, L., Duggirala, R., Olvera, R. L., Fox, P. T., Blangero, J. & Glahn, D. C., Jun 16 2010, In: Journal of Neuroscience. 30, 24, p. 8197-8202 6 p.

    Research output: Contribution to journalArticlepeer-review

    54 Scopus citations
  • 2007

    Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: The Family Investigation of Nephropathy and Diabetes (FIND)

    Iyengar, S. K., Abboud, H. E., Goddard, K. A. B., Saad, M. F., Adler, S. G., Arar, N. H., Bowden, D. W., Duggirala, R., Elston, R. C., Hanson, R. L., Ipp, E., Kao, W. H. L., Kimmel, P. L., Klag, M. J., Knowler, W. C., Meoni, L. A., Nelson, R. G., Nicholas, S. B., Pahl, M. V., Parekh, R. S. & 13 others, Quade, S. R. E., Rich, S. S., Rotter, J. I., Scavini, M., Schelling, J. R., Sedor, J. R., Sehgal, A. R., Shah, V. O., Smith, M. W., Taylor, K. D., Winkler, C. A., Zager, P. G. & Freedman, B. I., Jun 2007, In: Diabetes. 56, 6, p. 1577-1585 9 p.

    Research output: Contribution to journalArticlepeer-review

    117 Scopus citations
  • 2006

    A genomewide search finds major susceptibility loci for Gallbladder disease on chromosome 1 in Mexican Americans

    Puppala, S., Dodd, G. D., Fowler, S., Arya, R., Schneider, J., Farook, V. S., Granato, R., Dyer, T. D., Almasy, L. A., Jenkinson, C. P., Diehl, A. K., Stern, M. P., Blangero, J. C. & Duggirala, R., Mar 2006, In: American Journal of Human Genetics. 78, 3, p. 377-392 16 p.

    Research output: Contribution to journalArticlepeer-review

    88 Scopus citations
  • 2005

    A single nucleotide polymorphism in MGEA5 encoding O-GlcNAc-selective N-acetyl-β-D glucosaminidase is associated with type 2 diabetes im Mexican Americans

    Lehman, D. M., Fu, D. J., Freeman, A. B., Hunt, K. J., Leach, R. J., Johnson-Pais, T., Hamlington, J., Dyer, T. D., Arya, R., Abboud, H., Goring, H. HH., Duggirala, R., Blangero, J. C., Konrad, R. J. & Stern, M. P., Apr 2005, In: Diabetes. 54, 4, p. 1214-1221 8 p.

    Research output: Contribution to journalArticlepeer-review

    115 Scopus citations
  • 2002

    Factors of insulin resistance syndrome-related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic Mexican-Americans

    Arya, R., Blangero, J., Williams, K., Almasy, L., Dyer, T. D., Leach, R. J., O'Connell, P., Stern, M. P. & Duggirala, R., 2002, In: Diabetes. 51, 3, p. 841-847 7 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    158 Scopus citations
  • Heritability of anthropometric phenotypes in caste populations of Visakhapatnam, India

    Arya, R., Duggirala, R., Comuzzie, A. G., Puppala, S., Modem, S., Busi, B. R. & Crawford, M. H., 2002, In: Human Biology. 74, 3, p. 325-344 20 p.

    Research output: Contribution to journalArticlepeer-review

    36 Scopus citations
  • 2001

    Concordance between the CC chemokine receptor 5 genetic determinants that alter risks of transmission and disease progression in children exposed perinatally to human immunodeficiency virus

    Mangano, A., Gonzalez, E., Dhanda, R., Catano, G., Bamshad, M., Bock, A., Duggirala, R., Williams, K., Mummidi, S., Clark, R. A., Ahuja, S. S., Dolan, M. J., Bologna, R., Sen, L. & Ahuja, S. K., Jun 1 2001, In: Journal of Infectious Diseases. 183, 11, p. 1574-1585 12 p.

    Research output: Contribution to journalArticlepeer-review

    71 Scopus citations