Microbiology, Immunology & Molecular Genetics

Projects

Projects per year 1983 2019

• 1 Active
• 37 Not started
• 54 Finished

Projects per year

Search results

• Finished

  Role of host cell invasion in Mycoplasma genitalium persistent infection

  Baseman, J. B.

  12/17/15 → 11/30/17

  Project: Research project

• Evolution of the Morphology-Virulence Relationship in Candida Species

  Kadosh, D.

  National Institutes of Health

  6/15/15 → 5/31/17

  Project: Research project

  • Candida parapsilosis
  • Candida tropicalis
  • Candida
  • Candida albicans
  • candidiasis

• Pan-Fungal Essential Gene Discovery for Antifungal Targeting

  Wickes, B. L.

  National Institutes of Health

  5/1/15 → 4/30/17

  Project: Research project

  • essential genes
  • Agrobacterium radiobacter
  • drugs
  • drug design
  • insertional mutagenesis

• Cardiac microlesion formation during invasive pneumococcal disease

  Orihuela, C. J.

  National Institutes of Health

  11/1/14 → 10/31/19

  Project: Research project

  • Pneumococcal Infections
  • Streptococcus pneumoniae
  • Biofilms
  • Cardiac Myocytes
  • Streptococcus pneumoniae plY protein

• A novel role for the TLR signaling adaptor TRAM

  Berton, M. T.

  National Institutes of Health

  8/24/12 → 10/31/14

  Project: Research project

  • Toll-Like Receptors
  • Francisella tularensis
  • Listeriosis
  • Listeria monocytogenes
  • Tularemia

• Transcriptional Regulation by a Deacetylase, CobB, in a Periodontopathogen

  Kolodrubetz, D. J.

  National Institutes of Health

  4/1/12 → 2/28/15

  Project: Research project

  • Aggregatibacter actinomycetemcomitans
  • Lysine
  • Acetylation
  • Bacteria
  • Transcription Factors

• Statins protect against adverse cardiac events during pneumonia

  Orihuela, C. J.

  National Institutes of Health

  4/1/11 → 12/31/13

  Project: Research project

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Pneumonia
  • Streptococcus pneumoniae plY protein
  • Cardiac Myocytes
  • Cell Wall

• Determination of morphology and virulence in Candida albicans

  Kadosh, D.

  National Institutes of Health

  5/15/10 → 4/30/16

  Project: Research project

  • Candida albicans
  • virulence
  • infection
  • yeasts
  • pathogens

• Control of Candida albicans Filamentous Growth and Virulence

  Kadosh, D.

  National Institutes of Health

  9/30/09 → 8/31/11

  Project: Research project

  • Candida albicans
  • virulence
  • candidiasis
  • immunocompromised population
  • blastospores

• Age-associated Toll-like receptor dysfunction in the lungs

  Orihuela, C. J.

  National Institutes of Health

  4/1/09 → 3/31/12

  Project: Research project

  • Toll-Like Receptors
  • Pneumonia
  • Lung
  • Elderly
  • Alveolar Macrophages

• Mechanism of PsrP mediated adhesion

  Orihuela, C. J.

  National Institutes of Health

  1/23/09 → 12/31/14

  Project: Research project

  • Operon
  • Oxygen
  • Biofilms
  • Vaccination
  • Virulence

• Immune modulation mechanism mediated by poxvirus IL-18 binding protein

  Xiang, Y.

  National Institutes of Health

  9/24/08 → 3/31/19

  Project: Research project

  • Poxviridae
  • interleukin-18 binding protein
  • Interleukin-18
  • Immune Evasion
  • Vaccines

• Age-associated inflammation increases susceptibility to pneumococcal infection

  Orihuela, C. J.

  National Institutes of Health

  9/30/07 → 8/31/10

  Project: Research project

  • Pneumococcal Infections
  • Polymeric Immunoglobulin Receptors
  • Streptococcus pneumoniae
  • platelet activating factor receptor
  • Inflammation

• Host response to Yersinia pestis infection

  Dube, P. H.

  National Institutes of Health

  9/20/07 → 8/31/10

  Project: Research project

  • Plague
  • Yersinia pestis
  • Tissue Array Analysis
  • Cytokines
  • Chemokines

• Molecular Mechanism of Poxvirus Host Range Genes

  Xiang, Y.

  National Institutes of Health

  9/20/07 → 8/31/10

  Project: Research project

  • Poxviridae
  • Host Specificity
  • Ankyrin Repeat
  • Mitogen-Activated Protein Kinase 7
  • Orthopoxvirus

• Role of IL-6 in the Pathogenesis of Yersinia enterocolitica infection

  Dube, P. H.

  National Institutes of Health

  6/1/07 → 5/31/13

  Project: Research project

  • Yersinia Infections
  • Interleukin-6
  • Yersinia enterocolitica
  • Cytokines
  • Infection

• Novel Mycoplasma pneumoniae CARDS Toxin as Mediator of Airway Dysfuntion in Mice

  Dube, P. H., Coalson, J. J., Peters, J. I., Hart, P. J., Baseman, J. B., Hardy, R. D. & Cagle, M. P.

  National Institutes of Health

  7/1/06 → 7/31/16

  Project: Research project

  • Mycoplasma pneumoniae
  • Asthma
  • Adenosine Diphosphate
  • Mycoplasma Pneumonia
  • Mycoplasma

• T cell loss in a murine model for AIDS

  Scofield, V.

  National Institutes of Health

  9/30/05 → 2/29/08

  Project: Research project

  • 5-amino-1,2,3,4-tetrahydrophthalazine-1,4-dione
  • Murine Acquired Immunodeficiency Syndrome
  • Thymocytes
  • T-Lymphocytes
  • Thymus Gland

• Characterization of F. tularensis Virulence Genes

  Berton, M. T., Arulanandam, B. P., Teale, J., Wickes, B. & Klose, K.

  National Institutes of Health

  4/1/05 → 6/30/12

  Project: Research project

  • Tularemia
  • Francisella tularensis
  • Toll-Like Receptors
  • Immunity
  • Lung

• Chlamydia trachomatis proteomics

  Zhong, G.

  National Institutes of Health

  4/1/05 → 12/31/16

  Project: Research project

  • Chlamydia trachomatis
  • Proteomics
  • Genome
  • Subunit Vaccines
  • Antigens

• Chlamydial Manipulation of Host Apoptosis

  Zhong, G.

  National Institutes of Health

  7/1/04 → 9/30/12

  Project: Research project

  • apoptosis
  • Chlamydia
  • infection
  • pneumonia
  • uterine cervical neoplasms

• Anaerobic Regulatory Pathways in a Periodontopathogen

  Kolodrubetz, D. J.

  National Institutes of Health

  7/1/04 → 3/31/10

  Project: Research project

  • Actinobacillus actinomycetemcomitans
  • leukotoxins
  • oxygen
  • periodontitis
  • virulence

• Poxvirus immune modulators and the host Immune system

  Xiang, Y.

  National Institutes of Health

  4/1/03 → 3/31/06

  Project: Research project

  • Poxviridae
  • interleukin-18 binding protein
  • Interleukin-18
  • Immune System
  • human interleukin 18 protein

• Congenic strains of serotype A Cryptococcus neoformans

  Wickes, B. L.

  National Institutes of Health

  2/1/03 → 1/31/07

  Project: Research project

  • Cryptococcus neoformans
  • serotypes
  • mating types
  • infection
  • loci

• Role of Nitirc Oxide in Experimental Myasthenia Gravis

  Krolick, K. A.

  National Institutes of Health

  2/1/03 → 1/31/09

  Project: Research project

  • Autoimmune Experimental Myasthenia Gravis
  • Oxides
  • Cholinergic Receptors
  • Nitric Oxide
  • Inbred WF Rats

• Cooperative Mechanisms in IL-4-Induced Gene Expression

  Berton, M. T.

  National Institutes of Health

  12/1/02 → 11/30/08

  Project: Research project

  • Interleukin-4
  • Gene Expression
  • Serine
  • Phosphorylation
  • Janus Kinases

• Fluorescence, Chemiluminescence and Phosphor Imager

  Berton, M. T.

  National Institutes of Health

  3/1/02 → 2/28/03

  Project: Research project

  • chemiluminescence
  • typhoons
  • image analysis
  • fluorescence
  • pathogenesis

• Role of IL-1 in Yersinia Induced Intestinal Inflammation

  Dube, P. H.

  National Institutes of Health

  9/1/01 → 5/31/03

  Project: Research project

  • Yersinia
  • Interleukin-1
  • Yersinia Infections
  • Inflammation
  • Integration Host Factors

• Exacerbation of Atherosclerosis

  Zhong, G.

  National Institutes of Health

  7/1/01 → 6/30/06

  Project: Research project

  • atherosclerosis
  • pneumonia
  • inflammation
  • pathogenesis
  • animal models

• MECHANISMS OF CHLAMYDIAL EVASION OF IMMUNE RECOGNATION

  Zhong, G.

  National Institutes of Health

  7/15/00 → 11/30/16

  Project: Research project

  • Immune Evasion
  • Chlamydia
  • Proteasome Endopeptidase Complex
  • Peptide Hydrolases
  • Infection

• MYCOPLASMA PNEUMONIAE - AIRWAY INTERPLAY

  Baseman, J. B.

  National Institutes of Health

  4/1/00 → 3/31/07

  Project: Research project

  • Mycoplasma pneumoniae
  • Mycoplasma
  • Fibronectins
  • Pulmonary Surfactant-Associated Protein A
  • Respiratory System

• SECRETION MECHANISM OF A NOVEL C. RECTUS S-LAYER PROTEIN

  Kolodrubetz, D. J.

  National Institutes of Health

  4/1/00 → 3/31/04

  Project: Research project

  • Campylobacter rectus
  • S-layer proteins
  • Operon
  • Genes
  • Mutagenesis

• SAN ANTONIO SEXUALLY TRANSMITTED DISEASES COOPERATIVE RE

  Baseman, J. B., Piper, J., Jenson, H., Zhong, G., Alderete, J., Perdue, S. & Shain, R.

  National Institutes of Health

  9/30/99 → 8/31/12

  Project: Research project

  • Mycoplasma genitalium
  • Trichomonas vaginalis
  • sexually transmitted diseases
  • clinical examination
  • African Americans

• MYOCYTE RESPONSES DURING EXPERIMENTAL MYASTHENIA GRAVIS

  Krolick, K. A.

  National Institutes of Health

  7/1/99 → 6/30/03

  Project: Research project

  • Autoimmune Experimental Myasthenia Gravis
  • Cholinergic Receptors
  • Muscle Cells
  • Myasthenia Gravis
  • Antibodies

• MATING TYPE AND VIRULENCE IN CRYPTOCOCCUS NEOFORMANS

  Wickes, B. L.

  National Institutes of Health

  6/1/98 → 5/31/04

  Project: Research project

  • Cryptococcus neoformans
  • mating types
  • virulence
  • fruiting
  • genes

• DETERMINANTS OF DISEASE IN EXPERIMENTAL MYASTHENIA GRAVI

  Krolick, K. A.

  National Institutes of Health

  5/1/97 → 4/30/02

  Project: Research project

  • Autoimmune Experimental Myasthenia Gravis
  • Cholinergic Receptors
  • Antibodies
  • Inbred WF Rats
  • Myasthenia Gravis

• MECHANISMS OF MYCOPLASMA CYTADHERENCE AND INVASION

  Baseman, J. B.

  National Institutes of Health

  7/1/96 → 1/31/09

  Project: Research project

  • Mycoplasma genitalium
  • Mycoplasma
  • Mollicutes
  • pathogenicity
  • Mycoplasma penetrans

• CONTROL OF SWITCH RECOMBINATION BY CD40 LIGAND

  Berton, M. T.

  National Institutes of Health

  7/1/96 → 6/30/02

  Project: Research project

  • Immunoglobulin Genes
  • CD40 Ligand
  • Immunoglobulin Class Switching
  • Genetic Recombination
  • Interleukin-4

• ANTIBODIES THAT PLAY DIFFERENT ROLES IN MYASTHENIA GRAVI

  Krolick, K. A.

  National Institutes of Health

  12/1/95 → 11/30/99

  Project: Research project

  • Myasthenia Gravis
  • Anti-Idiotypic Antibodies
  • Antibodies
  • Isoelectric Focusing
  • Peptides

• REGULATION OF LEUKOTOXIN IN A ACTINOMYCETEMCOMITANS

  Kolodrubetz, D. J.

  National Institutes of Health

  9/1/93 → 8/31/02

  Project: Research project

  • leukotoxins
  • Actinobacillus actinomycetemcomitans
  • virulence
  • periodontitis
  • environmental law

• NEUROMUSCLUAR IMMUNOPATHOLOGY IN EAMG-RESISTANT RATS

  Krolick, K. A.

  National Institutes of Health

  5/1/93 → 4/30/98

  Project: Research project

  • immunopathology
  • T-lymphocytes
  • rats
  • antibodies
  • antigen-presenting cells

• INTERVENTIVE STRATEGIES FOR MYASTHENIA GRAVIS

  Infante, A. J., Krolick, K. A., Barohn, R. & Sanz, I.

  National Institutes of Health

  9/1/92 → 4/30/97

  Project: Research project

  • Myasthenia Gravis
  • Immunotoxins
  • myasthenia gravis
  • Cholinergic Receptors
  • T-Lymphocytes

• BIOLOGY OF AIDS-RELATED MYCOPLASMAS

  Baseman, J. B.

  National Institutes of Health

  9/1/92 → 8/31/96

  Project: Research project

  • Mycoplasma
  • adhesins
  • Biological Sciences
  • Mycoplasma pneumoniae
  • Mycoplasma pirum

• MUTATIONAL ANALYSIS OF THE FUNCTIONS OF HMG PROTEINS

  Kolodrubetz, D. J.

  National Institutes of Health

  5/1/92 → 4/30/97

  Project: Research project

  • High Mobility Group Proteins
  • Proteins
  • Chromatin
  • DNA
  • Gels

• CHARACTERIZATION OF DISEASE-CAUSING ANTIBODIES IN EAMG

  Krolick, K. A.

  National Institutes of Health

  12/1/89 → 11/30/94

  Project: Research project

  • Autoimmune Experimental Myasthenia Gravis
  • Cholinergic Receptors
  • Antibodies
  • Immunotoxins
  • Ricin

• MOLECULAR ANALYSIS OF ADHESIN P1

  Baseman, J. B.

  National Institutes of Health

  9/1/89 → 7/31/95

  Project: Research project

  • Pneumonia
  • Virulence
  • Epitopes
  • Gene Conversion
  • Respiratory Mucosa

• STUDIES OF SPERM-LYMPHOCYTE INTERACTION STRUCTURES

  Scofield, V.

  National Institutes of Health

  9/30/87 → 8/31/92

  Project: Research project

  • lymphocytes
  • spermatozoa
  • major histocompatibility complex
  • blood cells
  • graft rejection

• NEUROMUSCULAR IMMUNOPATHOLOGY IN EAMG

  Krolick, K. A.

  National Institutes of Health

  7/1/87 → 9/29/93

  Project: Research project

  • Cholinergic Receptors
  • T-Cell Antigen Receptor Specificity
  • Antibody Formation
  • T-Lymphocytes
  • Myasthenia Gravis

• MUTATIONAL ANALYSIS OF THE BIOLOGICAL FUNCTION OF HMG PR

  Kolodrubetz, D. J.

  National Institutes of Health

  12/1/84 → 5/31/88

  Project: Research project

  • High Mobility Group Proteins
  • Yeasts
  • Chromatin
  • Genes
  • Fungal Proteins

• MOLECULAR MECHANISMS OF MICROBIAL PATHOGENESIS

  Baseman, J. B., Eisenstein, B., Alderete, J. & Zhong, G.

  National Institutes of Health

  9/30/84 → 8/31/14

  Project: Research project