Joe R & Teresa Lozano School of Medicine

Research Output 1967 2019

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Review article
2019

Cause or casualty: The role of mitochondrial DNA in aging and age-associated disease

Chocron, E. S., Munkácsy, E. & Pickering, A. M., Feb 1 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 2, p. 285-297 13 p.

Research output: Contribution to journalReview article

Mitochondrial DNA
Mitochondrial Genome
Mitochondrial Genes
Oxidative Phosphorylation
Epigenomics

Congenital anomalies of the pulmonary arteries: An imaging overview

Escalon, J. G., Browne, L. P., Bang, T. J., Restrepo, C. S., Ocazionez, D. & Vargas, D., Jan 1 2019, In : British Journal of Radiology. 92, 1093, 20180185.

Research output: Contribution to journalReview article

Pulmonary Artery
Incidental Findings
Sudden Cardiac Death
Hemodynamics
Communication

Consensus statement by the American association of clinical endocrinologists and American college of endocrinology on the comprehensive type 2 diabetes management algorithm – 2019 executive summary

Garber, A. J., Abrahamson, M. J., Barzilay, J. I., Blonde, L., Bloomgarden, Z. T., Bush, M. A., Dagogo-Jack, S., Defronzo, R. A., Einhorn, D., Fonseca, V. A., Garber, J. R., Garvey, W. T., Grunberger, G., Handelsman, Y., Hirsch, I. B., Jellinger, P. S., McGill, J. B., Mechanick, J. I., Rosenblit, P. D. & Umpierrez, G. E., Jan 1 2019, In : Endocrine Practice. 25, 1, p. 69-100 32 p.

Research output: Contribution to journalReview article

Endocrinology
Type 2 Diabetes Mellitus
Consensus
Committee Membership
Randomized Controlled Trials

Evaluation of the Elekta Agility MLC performance using high-resolution log files

Kabat, C. N., Defoor, D. L., Myers, P., Kirby, N., Rasmussen, K., Saenz, D. L., Mavroidis, P., Papanikolaou, N. & Stathakis, S., Jan 1 2019, In : Medical Physics.

Research output: Contribution to journalReview article

Aptitude
Radiotherapy
Intensity-Modulated Radiotherapy
Friction
Gravitation

Multisystem imaging review of human schistosomiasis: characteristic imaging findings

Nepal, P., Ojili, V., Songmen, S., Batchala, P., Kumar, D. & Nagar, A. M., Mar 1 2019, In : Clinical Imaging. 54, p. 163-171 9 p.

Research output: Contribution to journalReview article

Schistosomiasis
Parasitic Diseases
Emigration and Immigration
Human Body
Testis

New concepts in diagnostics for invasive mycoses: Non-culture-based methodologies

Patterson, T. F. & Donnelly, J. P., Mar 1 2019, In : Journal of Fungi. 5, 1, 9.

Research output: Contribution to journalReview article

Open Access
mycoses
methodology
Aspergillus
Candida
well testing

Rapamycin and Alzheimer's disease: Time for a clinical trial?

Kaeberlein, M. & Galvan Hart, V., Jan 23 2019, In : Science Translational Medicine. 11, 476, eaar4289.

Research output: Contribution to journalReview article

Sirolimus
Alzheimer Disease
Clinical Trials
Animal Models
Pharmaceutical Preparations
Metformin
Exercise
Insulin Resistance
Inflammation
Clinical Trials
1 Citations (Scopus)

The multiple protective roles and molecular mechanisms of melatonin and its precursor N-acetylserotonin in targeting brain injury and liver damage and in maintaining bone health

Luo, C., Yang, Q., Liu, Y., Zhou, S., Jiang, J., Reiter, R. J., Bhattacharya, P., Cui, Y., Yang, H., Ma, H., Yao, J., Lawler, S. E., Zhang, X., Fu, J., Rozental, R., Aly, H., Johnson, M. D., Chiocca, E. A. & Wang, X., Jan 1 2019, In : Free Radical Biology and Medicine. 130, p. 215-233 19 p.

Research output: Contribution to journalReview article

Melatonin
Liver
Brain Injuries
Brain
Bone
3 Citations (Scopus)

Therapeutic potential of melatonin related to its role as an autophagy regulator: A review

Boga, J. A., Caballero, B., Potes, Y., Perez-Martinez, Z., Reiter, R. J., Vega-Naredo, I. & Coto-Montes, A., Jan 1 2019, In : Journal of Pineal Research. 66, 1, e12534.

Research output: Contribution to journalReview article

Autophagy
Melatonin
Pathology
Physiological Phenomena
Endoplasmic Reticulum Stress

The role of melatonin in targeting cell signaling pathways in neurodegeneration

Shukla, M., Chinchalongporn, V., Govitrapong, P. & Reiter, R. J., Jan 1 2019, In : Annals of the New York Academy of Sciences.

Research output: Contribution to journalReview article

Cell signaling
Melatonin
Neurodegenerative Diseases
Neurodegenerative diseases
Proteostasis Deficiencies

The therapeutic role of long non-coding RNAs in human diseases: A focus on the recent insights into autophagy

Barangi, S., Hayes, A. W., Reiter, R. J. & Karimi, G., Apr 1 2019, In : Pharmacological Research. 142, p. 22-29 8 p.

Research output: Contribution to journalReview article

Long Noncoding RNA
Autophagy
Therapeutics
Biological Phenomena
Untranslated RNA

Tutorial on lipidomics

Wang, J., Wang, C. & Han, X., Jan 1 2019, In : Analytica Chimica Acta.

Research output: Contribution to journalReview article

body fluid
Body fluids
Body Fluids
Biological systems
Mass spectrometry

Upcycling umbilical cords: bridging regenerative medicine with neonatology

Moreira, A. G., Alayli, Y., Balgi, S., Winter, C., Kahlenberg, S., Mustafa, S. & Hornsby, P. J., Apr 18 2019, In : Journal of Maternal-Fetal and Neonatal Medicine. 32, 8, p. 1378-1387 10 p.

Research output: Contribution to journalReview article

Neonatology
Regenerative Medicine
Umbilical Cord
Mesenchymal Stromal Cells
Premature Infants
2018

Acid Peptic Disease

Kempenich, J. W. & Sirinek, K. R., Oct 1 2018, In : Surgical Clinics of North America. 98, 5, p. 933-944 12 p.

Research output: Contribution to journalReview article

Digestion
Acids
Peptic Ulcer Perforation
Peptic Ulcer
Patient Care
1 Citations (Scopus)

Ambivalence: A key to clinical trial participation?

Chilton, J. A., Rasmus, M. L., Lytton, J., Kaplan, C. D., Jones, L. A. & Hurd, T. C., Aug 10 2018, In : Frontiers in Oncology. 8, AUG, 300.

Research output: Contribution to journalReview article

Clinical Trials
Motivational Interviewing
Decision Making
Delivery of Health Care
Medical Oncology

Antiepileptic drugs and suicide-related behavior: Is it the drug or comorbidity?

Raju Sagiraju, H. K., Wang, C., Amuan, M. E., Van Cott, A. C., Altalib, H. H. & Pugh, M. J. V., Aug 1 2018, In : Neurology: Clinical Practice. 8, 4, p. 331-339 9 p.

Research output: Contribution to journalReview article

Anticonvulsants
Suicide
Comorbidity
Pharmaceutical Preparations
Drug Users
3 Citations (Scopus)
dementia
morbidity
Dementia
incidence
Morbidity
2 Citations (Scopus)
Public Health Practice
Publication Bias
Therapeutics
Reproducibility of Results
Sample Size
Monoclonal antibodies
Hospital Emergency Service
Adrenal Cortex Hormones
Asthma
Lung
8 Citations (Scopus)

Cardiovascular disease in survivors of childhood cancer: Insights into epidemiology, pathophysiology, and prevention

Armenian, S. H., Armstrong, G. T., Aune, G., Chow, E. J., Ehrhardt, M. J., Ky, B., Moslehi, J., Mulrooney, D. A., Nathan, P. C., Ryan, T. D., Van Der Pal, H. J., Van Dalen, E. C. & Kremer, L. C. M., Jul 20 2018, In : Journal of Clinical Oncology. 36, 21, p. 2135-2144 10 p.

Research output: Contribution to journalReview article

Survivors
Epidemiology
Cardiovascular Diseases
Neoplasms
Therapeutics
1 Citations (Scopus)

Chemoprevention in Prostate Cancer: Current Perspective and Future Directions

Rivero, J. R., Thompson, I. M., Liss, M. A. & Kaushik, D., Oct 1 2018, In : Cold Spring Harbor perspectives in medicine. 8, 10

Research output: Contribution to journalReview article

Chemoprevention
Prostatic Neoplasms
Vitamins
Nutrients
Oxidoreductases
3 Citations (Scopus)

Connexins and pannexins: Important players in tumorigenesis, metastasis and potential therapeutics

Graham, S. V., Jiang, J. X. & Mesnil, M., Jun 1 2018, In : International Journal of Molecular Sciences. 19, 6, 1645.

Research output: Contribution to journalReview article

Connexins
Cell growth
metastasis
Carcinogenesis
cancer
94 Citations (Scopus)

Consensus statement by the American association of clinical endocrinologists and American college of endocrinology on the comprehensive type 2 diabetes management algorithm - 2018 executive summary

Garber, A. J., Abrahamson, M. J., Barzilay, J. I., Blonde, L., Bloomgarden, Z. T., Bush, M. A., Dagogo-Jack, S., Defronzo, R. A., Einhorn, D., Fonseca, V. A., Garber, J. R., Garvey, W. T., Grunberger, G., Handelsman, Y., Hirsch, I. B., Jellinger, P. S., McGill, J. B., Mechanick, J. I., Rosenblit, P. D. & Umpierrez, G. E., Jan 1 2018, In : Endocrine Practice. 24, 1, p. 91-120 30 p.

Research output: Contribution to journalReview article

Endocrinology
Type 2 Diabetes Mellitus
Consensus
Committee Membership
Randomized Controlled Trials
9 Citations (Scopus)

Cystic fibrosis foundation pulmonary guidelines: Use of cystic fibrosis transmembrane conductance regulator modulator therapy in patients with cystic fibrosis

Ren, C. L., Morgan, R. L., Oermann, C., Resnick, H. E., Brady, C., Campbell, A., DeNagel, R., Guill, M., Hoag, J., Lipton, A., Newton, T., Peters, S., Willey-courand, D. B. & Naureckas, E. T., Mar 1 2018, In : Annals of the American Thoracic Society. 15, 3, p. 271-280 10 p.

Research output: Contribution to journalReview article

Cystic Fibrosis Transmembrane Conductance Regulator
Cystic Fibrosis
Guidelines
Forced Expiratory Volume
United States Food and Drug Administration
16 Citations (Scopus)

Diabetic retinopathy pathogenesis and the ameliorating effects of melatonin; involvement of autophagy, inflammation and oxidative stress

Dehdashtian, E., Mehrzadi, S., Yousefi, B., Hosseinzadeh, A., Reiter, R. J., Safa, M., Ghaznavi, H. & Naseripour, M., Jan 15 2018, In : Life Sciences. 193, p. 20-33 14 p.

Research output: Contribution to journalReview article

Oxidative stress
Autophagy
Diabetic Retinopathy
Melatonin
Oxidative Stress

Distinguishing Comorbidity, Disability, and Frailty

Espinoza, S. E., Quiben, M. & Hazuda, H. P., Dec 1 2018, In : Current Geriatrics Reports. 7, 4, p. 201-209 9 p.

Research output: Contribution to journalReview article

Comorbidity
Chronic Disease
Public Health
Cross-Sectional Studies
Delivery of Health Care
2 Citations (Scopus)

Embracing uncertainty, managing complexity: Applying complexity thinking principles to transformation efforts in healthcare systems

Khan, S., Vandermorris, A., Shepherd, J., Begun, J. W., Lanham, H. L., Uhl-Bien, M. & Berta, W., Mar 21 2018, In : BMC Health Services Research. 18, 1, 192.

Research output: Contribution to journalReview article

Uncertainty
Delivery of Health Care
Systems Analysis
Lenses
Patient Care
1 Citations (Scopus)

Exploring the negative likelihood ratio and how it can be used to minimize false-positives in breast imaging

Yang, W. T., Parikh, J. R., Thomas Stavros, A., Otto, P. M. & Maislin, G., Feb 1 2018, In : American Journal of Roentgenology. 210, 2, p. 301-306 6 p.

Research output: Contribution to journalReview article

Breast
Benchmarking
Radiology
Biopsy
Radiologists

From the clinical mycology laboratory: New species and changes in fungal taxonomy and nomenclature

Wiederhold, N. & Gibas, C. F. C., Dec 1 2018, In : Journal of Fungi. 4, 4, 138.

Research output: Contribution to journalReview article

Open Access
mycology
nomenclature
new species
taxonomy
fungi
6 Citations (Scopus)

Fungal infections in animals: A patchwork of different situations

Seyedmousavi, S., Bosco, S., De Hoog, S., Ebel, F., Elad, D., Gomes, R. R., Jacobsen, I. D., Martel, A., Mignon, B., Pasmans, F., Piecková, E., Rodrigues, A. M., Singh, K., Vicente, V. A., Wibbelt, G., Wiederhold, N. & Guillot, J., Apr 1 2018, In : Medical Mycology. 56, p. S165-S187

Research output: Contribution to journalReview article

Mycoses
Zoonoses
Infection
Vertebrates
Fungi
3 Citations (Scopus)

Hypoglycemia after gastric bypass surgery: Current concepts and controversies

Salehi, M., Vella, A., McLaughlin, T. & Patti, M. E., Jan 1 2018, In : Journal of Clinical Endocrinology and Metabolism. 103, 8, p. 2815-2826 12 p.

Research output: Contribution to journalReview article

Gastric Bypass
Hypoglycemia
Surgery
Accidents
Physicians
2 Citations (Scopus)

Immunotherapy in colorectal cancer: For the select few or all?

Arora, S. P. & Mahalingam, D., Feb 1 2018, In : Journal of Gastrointestinal Oncology. 9, 1, p. 170-179 10 p.

Research output: Contribution to journalReview article

Immunotherapy
Colorectal Neoplasms
Microsatellite Instability
Therapeutics
2 Citations (Scopus)

Insulin resistance the link between t2dm and cvd: Basic mechanisms and clinical implications

Abdul-ghani, M. A., Jayyousi, A., Defronzo, R. A., Asaad, N. & Al-Suwaidi, J., Jan 1 2018, In : Current Vascular Pharmacology. 17, 2, p. 153-163 11 p.

Research output: Contribution to journalReview article

Type 2 Diabetes Mellitus
Insulin Resistance
Cardiovascular Diseases
Multiple Abnormalities
Glucose

Joint statement from the American College of Surgeons Committee on Trauma (ACS COT) and the American College of Emergency Physicians (ACEP) regarding the clinical use of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)

Brenner, M., Bulger, E. M., Perina, D. G., Henry, S., Kang, C. S., Rotondo, M. F., Chang, M. C., Weireter, L. J., Coburn, M., Winchell, R. J. & Stewart, R. M., Jan 1 2018, In : Trauma Surgery and Acute Care Open. 3, 1, e000154.

Research output: Contribution to journalReview article

Open Access
Balloon Occlusion
Aorta
Wounds and Injuries

Kidney atrophy vs hypertrophy in diabetes: which cells are involved?

Habib, S. L., Jul 18 2018, In : Cell Cycle. 17, 14, p. 1683-1687 5 p.

Research output: Contribution to journalReview article

Hypertrophy
Atrophy
Kidney
Nephrons
Diabetic Nephropathies

Latitude, Vitamin D, Melatonin, and Gut Microbiota Act in Concert to Initiate Multiple Sclerosis: A New Mechanistic Pathway

Ghareghani, M., Reiter, R. J., Zibara, K. & Farhadi, N., Jan 1 2018, In : Frontiers in Immunology. 9, 1 p.

Research output: Contribution to journalReview article

Melatonin
Vitamin D
Multiple Sclerosis
Vitamin D Deficiency
Sunlight

Lipidomics Reveals Changes in Metabolism, Indicative of Anesthetic-Induced Neurotoxicity in Developing Brains

Wang, C., Wang, C., Liu, F., Rainosek, S., Patterson, T. A., Slikker, W. & Han, X., Sep 17 2018, In : Chemical Research in Toxicology. 31, 9, p. 825-835 11 p.

Research output: Contribution to journalReview article

Metabolism
Anesthetics
Brain
Lipids
Brain Injuries

Making sense of pharmacology: Inverse agonism and functional selectivity

Berg, K. A. & Clarke, W. P., Oct 1 2018, In : International Journal of Neuropsychopharmacology. 21, 10, p. 962-977 16 p.

Research output: Contribution to journalReview article

Pharmacology
Pharmaceutical Preparations
Ligands
Research
Medicine
17 Citations (Scopus)

Melatonin: A versatile protector against oxidative DNA damage

Galano, A., Tan, D. X. & Reiter, R. J., Jan 1 2018, In : Molecules. 23, 3, 530.

Research output: Contribution to journalReview article

melatonin
protectors
Melatonin
DNA Damage
deoxyribonucleic acid
20 Citations (Scopus)

Melatonin: A Cutaneous Perspective on its Production, Metabolism, and Functions

Slominski, A. T., Hardeland, R., Zmijewski, M. A., Slominski, R. M., Reiter, R. J. & Paus, R., Mar 1 2018, In : Journal of Investigative Dermatology. 138, 3, p. 490-499 10 p.

Research output: Contribution to journalReview article

Melatonin
Metabolism
Skin
Skin Neoplasms
Repair
10 Citations (Scopus)

Melatonin and its metabolites vs oxidative stress: From individual actions to collective protection

Galano, A. & Reiter, R. J., Aug 1 2018, In : Journal of Pineal Research. 65, 1, e12514.

Research output: Contribution to journalReview article

Melatonin
Oxidative Stress
Antioxidants
Defense Mechanisms
Hydrogen

Microtubules and axon regeneration in C. elegans

Chen, L., Sep 1 2018, In : Molecular and Cellular Neuroscience. 91, p. 160-166 7 p.

Research output: Contribution to journalReview article

Microtubules
Axons
Regeneration
Neuroanatomy
Spinal Cord Injuries

Minimally invasive plate osteosynthesis of humeral shaft fractures: Current state of the art

Tetsworth, K., Hohmann, E. & Glatt, V., Jan 1 2018, In : Journal of the American Academy of Orthopaedic Surgeons. 26, 18, p. 652-661 10 p.

Research output: Contribution to journalReview article

Humeral Fractures
Radial Nerve
Closed Fractures
Shoulder Pain
Wounds and Injuries

Molecular diagnostics in medical mycology

Wickes, B. L. & Wiederhold, N., Dec 1 2018, In : Nature Communications. 9, 1, 5135.

Research output: Contribution to journalReview article

Mycology
Molecular Pathology
Mycoses
infectious diseases
Fungi
166 Citations (Scopus)

Molecular mechanisms of cell death: Recommendations of the Nomenclature Committee on Cell Death 2018

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., Annicchiarico-Petruzzelli, M., Antonov, A. V., Arama, E., Baehrecke, E. H., Barlev, N. A., Bazan, N. G., Bernassola, F., Bertrand, M. J. M., Bianchi, K., Blagosklonny, M. V. & 149 othersBlomgren, K., Borner, C., Boya, P., Brenner, C., Campanella, M., Candi, E., Carmona-Gutierrez, D., Cecconi, F., Chan, F. K. M., Chandel, N. S., Cheng, E. H., Chipuk, J. E., Cidlowski, J. A., Ciechanover, A., Cohen, G. M., Conrad, M., Cubillos-Ruiz, J. R., Czabotar, P. E., D'Angiolella, V., Dawson, T. M., Dawson, V. L., De Laurenzi, V., De Maria, R., Debatin, K. M., Deberardinis, R. J., Deshmukh, M., Di Daniele, N., Di Virgilio, F., Dixit, V. M., Dixon, S. J., Duckett, C. S., Dynlacht, B. D., El-Deiry, W. S., Elrod, J. W., Fimia, G. M., Fulda, S., García-Sáez, A. J., Garg, A. D., Garrido, C., Gavathiotis, E., Golstein, P., Gottlieb, E., Green, D. R., Greene, L. A., Gronemeyer, H., Gross, A., Hajnoczky, G., Hardwick, J. M., Harris, I. S., Hengartner, M. O., Hetz, C., Ichijo, H., Jäättelä, M., Joseph, B., Jost, P. J., Juin, P. P., Kaiser, W., Karin, M., Kaufmann, T., Kepp, O., Kimchi, A., Kitsis, R. N., Klionsky, D. J., Knight, R. A., Kumar, S., Lee, S. W., Lemasters, J. J., Levine, B., Linkermann, A., Lipton, S. A., Lockshin, R. A., López-Otín, C., Lowe, S. W., Luedde, T., Lugli, E., MacFarlane, M., Madeo, F., Malewicz, M., Malorni, W., Manic, G., Marine, J. C., Martin, S. J., Martinou, J. C., Medema, J. P., Mehlen, P., Meier, P., Melino, S., Miao, E. A., Molkentin, J. D., Moll, U. M., Muñoz-Pinedo, C., Nagata, S., Nuñez, G., Oberst, A., Oren, M., Overholtzer, M., Pagano, M., Panaretakis, T., Pasparakis, M., Penninger, J. M., Pereira, D. M., Pervaiz, S., Peter, M. E., Piacentini, M., Pinton, P., Prehn, J. H. M., Puthalakath, H., Rabinovich, G. A., Rehm, M., Rizzuto, R., Rodrigues, C. M. P., Rubinsztein, D. C., Rudel, T., Ryan, K. M., Sayan, E., Scorrano, L., Shao, F., Shi, Y., Silke, J., Simon, H. U., Sistigu, A., Stockwell, B. R., Strasser, A., Szabadkai, G., Tait, S. W. G., Tang, D., Tavernarakis, N., Thorburn, A., Tsujimoto, Y., Turk, B., Vanden Berghe, T., Vandenabeele, P., Vander Heiden, M. G., Villunger, A., Virgin, H. W., Vousden, K. H., Vucic, D., Wagner, E. F., Walczak, H., Wallach, D., Wang, Y., Wells, J. A., Wood, W., Yuan, J., Zakeri, Z., Zhivotovsky, B., Zitvogel, L., Melino, G. & Kroemer, G., Mar 1 2018, In : Cell Death and Differentiation. 25, 3, p. 486-541 56 p.

Research output: Contribution to journalReview article

Terminology
Cell Death
Apoptosis
Cell Aging
Autophagy
2 Citations (Scopus)

Molecular regulation of MCU: Implications in physiology and disease

Nemani, N., Shanmughapriya, S. & Muniswamy, M., Sep 1 2018, In : Cell Calcium. 74, p. 86-93 8 p.

Research output: Contribution to journalReview article

Divalent Cations
Mitochondrial Membranes
Membrane Potentials
Energy Metabolism
Mitochondria
1 Citations (Scopus)

Paraoxonase (PON)-1: A brief overview on genetics, structure, polymorphisms and clinical relevance

Shunmoogam, N., Naidoo, P. & Chilton, R. J., Jun 18 2018, In : Vascular Health and Risk Management. 14, p. 137-143 7 p.

Research output: Contribution to journalReview article

Aryldialkylphosphatase
Genetic Structures
Esterases
HDL Lipoproteins
Atherosclerosis
2 Citations (Scopus)

PELP1: a key mediator of oestrogen signalling and actions in the brain

Thakkar, R., Sareddy, G. R., Zhang, Q., Wang, R., Vadlamudi, R. K. & Brann, D., Feb 1 2018, In : Journal of Neuroendocrinology. 30, 2, e12484.

Research output: Contribution to journalReview article

Estrogens
Brain
Proteins
human PELP1 protein
Chromatin Assembly and Disassembly
1 Citations (Scopus)

Petition to replace current OGTT criteria for diagnosing prediabetes with the 1-hour post-load plasma glucose ≥ 155 mg/dl (8.6 mmol/L)

Bergman, M., Manco, M., Sesti, G., Dankner, R., Pareek, M., Jagannathan, R., Chetrit, A., Abdul-ghani, M. A., Buysschaert, M., Olsen, M. H., Nilsson, P. M., Medina, J. L., Roth, J., Groop, L., del Prato, S., Raz, I. & Ceriello, A., Dec 1 2018, In : Diabetes Research and Clinical Practice. 146, p. 18-33 16 p.

Research output: Contribution to journalReview article

Prediabetic State
Glucose Tolerance Test
Glucose
Life Style
Mortality