Greehey Children's Cancer Research Institute

Projects

Projects per year 2004 2007 2009 2014 2020

• 10 Finished
• 40 Not started

Projects per year

Search results

• Quantitative Proteomic Analysis of the Secretory Pattern of Senescent Cells

  Shiio, Y.

  National Institutes of Health

  2/15/07 → 1/31/10

  Project: Research project

  • Proteomics 100%
  • Neoplasms 42%
  • Fibroblasts 32%
  • Cellular Senescence 31%
  • Pathology 27%

• A screen for damage response genes using recombination

  Bishop, A. J.

  National Institutes of Health

  9/1/04 → 5/31/10

  Project: Research project

  • homologous recombination 100%
  • Drosophila 49%
  • RNA interference 44%
  • genes 27%
  • mentoring 22%

• Alternative splicing regulation in perspective: A global analysis of exon skippin

  Penalva, L. O.

  National Institutes of Health

  4/14/09 → 2/28/12

  Project: Research project

  • alternative splicing 100%
  • RNA-binding proteins 80%
  • exons 73%
  • regulatory sequences 49%
  • RNA 21%

• Catenins: A role in spertmatogenesis and sperm maturation

  Rao, M. K.

  National Institutes of Health

  9/30/09 → 6/30/13

  Project: Research project

  • Catenins 100%
  • Sperm Maturation 82%
  • Germ Cells 78%
  • Sertoli Cells 56%
  • Spermatids 39%

• Secretome Proteomics for VHL Tumor Biomarker Discovery

  Shiio, Y.

  National Institutes of Health

  8/1/09 → 7/31/13

  Project: Research project

  • Tumor Biomarkers 100%
  • von Hippel-Lindau Disease 78%
  • Proteomics 76%
  • Renal Cell Carcinoma 43%
  • Serum 36%

• Analysis of the VHL-HIF hydroxylase pathway

  Shiio, Y.

  National Institutes of Health

  9/25/07 → 7/31/14

  Project: Research project

  • ubiquitin 100%
  • hypoxia 84%
  • ligases 71%
  • ubiquitination 69%
  • oncogene proteins 52%

• Determination of Musashi1/CD44v6 signaling in mesenchymal glioma stem cells

  Penalva, L. O., Nakano, I. & Penalva, L. O.

  National Institutes of Health

  1/1/14 → 12/31/15

  Project: Research project

  • Glioblastoma 100%
  • Glioma 89%
  • Mesenchymal Stem Cells 71%
  • Small Interfering RNA 31%
  • Stem Cells 27%

• Importance of Androgen regulated miRNAs in male fertility

  Rao, M. K.

  National Institutes of Health

  7/15/14 → 4/30/16

  Project: Research project

  • Androgens 100%
  • MicroRNAs 77%
  • Fertility 77%
  • Sertoli Cells 72%
  • Germ Cells 52%

• Computational Methods for Deep Sequencing Based RBP Binding Motif Characterizatio

  Penalva, L. O., Smith, A. D. & Penalva, L. O.

  National Institutes of Health

  12/1/10 → 7/31/18

  Project: Research project

  • RNA-Binding Proteins 100%
  • High-Throughput Nucleotide Sequencing 80%
  • Binding Sites 68%
  • Chromatin Immunoprecipitation Sequencing 28%
  • Computational methods 25%

• miRNAs:Safe and effective therapeutic adjuvants for treating drug resistant TNBC

  Rao, M. K. & Vadlamudi, R. K.

  National Institutes of Health

  2/1/15 → 1/31/20

  Project: Research project

  • Triple Negative Breast Neoplasms 100%
  • MicroRNAs 87%
  • Paclitaxel 32%
  • Pharmaceutical Preparations 27%
  • Therapeutics 15%

• GORDON CONFERENCE--CANCER CHEMOTHERAPY

  Houghton, P. J.

  Project: Research project

• Alternative splicing regulation in perspective: A global analysis of exon skippin

  Penalva, L. O.

  Project: Research project

• THERAPY OF COLON CANCER WITH DIARYLSULFONYLUREAS

  Houghton, P. J.

  Project: Research project

• Comparing and contrasting the biology of damage survival at a genomic level

  Bishop, A. J.

  Project: Research project

• INVOLVEMENT OF P53 AND ATM IN HOMOLOGOUS RECOMBINATION

  Bishop, A. J.

  Project: Research project

• CHEMOTHERAPY OF CHILDHOOD RHABDOMYOSARCOMA

  Houghton, P. J.

  Project: Research project

• An Integrated Biochemical and Structural Approach to Delineating the Biology of EWSR1

  Libich, D. S.

  Project: Research project

• microRNA regulation of drug sensitivity in non-small cell lung cancer

  Pertsemlidis, A.

  Project: Research project

• Analysis of the VHL-HIF hydroxylase pathway

  Shiio, Y.

  Project: Research project

• Enhancing MAPK-targeted Therapy in PDX Models of BRAF-Mutant Pediatric Brain Tumors

  Burma, S. & Houghton, P. J.

  Project: Research project

• Dysregulated transcription processes in Ewing sarcoma

  Bishop, A. J.

  Project: Research project

• Musashi1 and miR-137 antagonism: impact on neurogenesis and diseases

  Penalva, L. O. & Cearley, E. K.

  Project: Research project

• Determination of Musashi1/CD44v6 signaling in mesenchymal glioma stem cells

  Penalva, L. O.

  Project: Research project

• A computational framework for global analysis of translation regulation

  Penalva, L. O.

  Project: Research project

• Symptom Screening Linked to Care Pathways for Children with Cancer: a Cluster Randomized Trial

  Grimes, A. C.

  Project: Research project

• Pediatric Preclinical Testing Consortium: Research Programs non-CNS

  Houghton, P. J.

  Project: Research project

• Secretome Proteomics for VHL Tumor Biomarker Discovery

  Shiio, Y.

  Project: Research project

• Improving Therapeutic Approaches for RAS-driven Embryonal Rhabdomyosarcoma

  Vaseva, A.

  Project: Research project

• MODIFIERS OF ARMADILLO FUNCTION

  Mcewen, D. G.

  Project: Research project

• Improving etoposide treatment of Ewing's sarcoma

  Bishop, A. J.

  Project: Research project

• A novel oncogenic driver in Ewing sarcoma

  Shiio, Y.

  Project: Research project

• A role for notch in self renewal in embryonal rhabdomyosarcoma

  Ignatius, M. S.

  Project: Research project

• Mechanism-based Targeting of the RNA Processing Machinery of SARS-CoV-2

  Gupta, Y. K.

  Project: Research project

• Quantitative Proteomic Analysis of the Secretory Pattern of Senescent Cells

  Shiio, Y.

  Project: Research project

• Formation of Neocentromere at a DSB Site

  Kitagawa, K.

  Project: Research project

• Kinetochore Function and Cell Cycle Progression Revision

  Kitagawa, K.

  Project: Research project

• Cancer Drugs Active Against Stress Signaling Pathways

  Houghton, P. J.

  Project: Research project

• XENOGRAFT STUDIES

  Houghton, P. J.

  Project: Research project

• Studies of Childhood Solid Tumors

  Houghton, P. J. & Houghton, P. J.

  Project: Research project

• Studies of Childhood Sarcomas

  Houghton, P. J. & Houghton, P. J.

  Project: Research project

• High Throughput DNA Sequencer: Illumina HiSeq 3000 Sequencer

  Lai, Z.

  Project: Research project

• Splicing factors and RNA processing alternations: exploring new players in glioblastoma development

  Penalva, L. O.

  Project: Research project

• A role for notch in self renewal in embryonal rhabdomyosarcoma

  Ignatius, M. S.

  Project: Research project

• A Testing Program to Identify Novel Agents for Treatment of Pediatric and AYA High-Risk Sarcoma, Kidney and Liver Cancer

  Houghton, P. J.

  Project: Research project

• MTOR as a Therapeutic Target in Childhood Cancer

  Houghton, P. J.

  Project: Research project

• A screen for damage response genes using recombination

  Bishop, A. J.

  Project: Research project

• Rapamycin-Induced Selective Apoptosis in Malignant Cells

  Houghton, P. J. & Houghton, P. J.

  Project: Research project

• Preclinical Pharmacokinetic and Pharmacological Studies of Antitumor and other Th

  Houghton, P. J.

  Project: Research project

• Therapeutic Exploitation of Mutant BRAF for Astrocytoma

  Houghton, P. J.

  Project: Research project

• FoXM1 inhibition: a novel therapeutic avenue to treat breast cancers

  Vadlamudi, R. K., Rao, M. K. & Vadlamudi, R. K.

  Project: Research project