Research output per year
Research output per year
Organization profile
Organization profile
Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (GCCRI) mission has been to advance scientific knowledge relevant to childhood cancer, contribute to the understanding of causes of childhood cancer, and accelerate the translation of knowledge into novel therapies. Through discovery, development and dissemination of new scientific knowledge, GCCRI strives to have a national and global impact on the problem of childhood cancer. Our mission consists of three key areas — research, clinical and education.
Greehey Children’s Cancer Research Institute does not participate directly in patient care, but interacts with members of the Division of Pediatric Hematology-Oncology to provide support for clinical research. Research services at the Institute include: genome sequencing, small animal imaging and computational biology and bioinformatics.
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Dive into the research topics where Greehey Children's Cancer Research Institute is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice
Yang, Y., Jn-Simon, N., He, Y., Sun, C., Zhang, P., Hu, W., Tian, T., Zeng, H., Basha, S., Huerta, A. S., Sun, L. Z., Yin, X. M., Hromas, R., Zheng, G., Pi, L. & Zhou, D., Mar 2025, In: Nature Aging. 5, 3, p. 386-400 15 p., 15691.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Age-Dependent Bi-Phasic Dynamics of Ly49+CD8+ Regulatory T Cell Population
Srinivasan, S., Mishra, S., Fan, K. K. H., Wang, L., Im, J., Segura, C., Mukherjee, N., Huang, G., Rao, M., Ma, C. & Zhang, N., Apr 2025, In: Aging cell. 24, 4, e14461.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A novel regimen for pancreatic ductal adenocarcinoma targeting MEK, BCL-xL, and EGFR
Han, S., Tushoski-Alemán, G. W., Zhang, P., Zheng, G., Zhou, D., Huo, Z., Licht, J., George, T. J., Allegra, C., Trevino, J. G. & Hughes, S. J., Jan 2025, In: Neoplasia (United States). 59, 101070.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations
Datasets
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Structure of the ATPrS-Mre11/Rad50-DNA complex
Liu, Y. (Contributor), Sung, S. (Contributor), Kim, Y. (Contributor), Li, F. (Contributor), Gwon, G. (Contributor), Jo, A. (Contributor), Kim, A.-K. (Contributor), Kim, T. (Contributor), Song, O.-K. (Contributor), Lee, S. E. (Contributor) & Cho, Y. (Contributor), Protein Data Bank (PDB), Mar 2 2016
DOI: 10.2210/pdb5F3W/pdb, https://www.wwpdb.org/pdb?id=pdb_00005f3w
Dataset
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The paralogues MAGOH and MAGOHB are oncogenic factors in high-grade gliomas and safeguard the splicing of cell division and cell cycle genes
Barreiro, R. A. S. (Creator), Guardia, G. D. A. (Creator), Meliso, F. M. (Creator), Lei, X. (Creator), Li, W.-Q. (Creator), Savio, A. (Creator), Fellermeyer, M. (Creator), Conceição, H. B. (Creator), Mercuri, R. L. V. (Creator), Landry, T. (Creator), Qiao, M. (Creator), Blazquez, L. (Creator), Ule, J. (Creator), Penalva, L. O. F. (Creator) & Galante, P. A. F. (Creator), Taylor & Francis, 2023
DOI: 10.6084/m9.figshare.23460154, https://tandf.figshare.com/articles/dataset/The_paralogues_MAGOH_and_MAGOHB_are_oncogenic_factors_in_high-grade_gliomas_and_safeguard_the_splicing_of_cell_division_and_cell_cycle_genes/23460154
Dataset
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Barriers to symptom management care pathway implementation in pediatric Cancer
Grimes, A. (Creator), Vettese, E. (Creator), Klesges, L. M. (Creator), Sung, L. (Creator) & Dupuis, L. L. (Creator), Figshare, 2021
DOI: 10.6084/m9.figshare.c.5655118.v1, https://springernature.figshare.com/collections/Barriers_to_symptom_management_care_pathway_implementation_in_pediatric_Cancer/5655118/1
Dataset