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2020

Apical periodontitis-induced mechanical allodynia: A mouse model to study infection-induced chronic pain conditions

Mohaved, S. B., Shilpa, G., Li, Q., Austah, O., Bendele, M., Brock, R. & Ruparel, N. B., 2020, In : Molecular Pain. 16

Research output: Contribution to journalArticle

Open Access

A Volumetric Assessment of External Cervical Resorption Cases and Its Correlation to Classification, Treatment Planning, and Expected Prognosis

Matny, L. E., Ruparel, N. B., Levin, M. D., Noujeim, M. E. & Diogenes, A., Aug 2020, In : Journal of endodontics. 46, 8, p. 1052-1058 7 p.

Research output: Contribution to journalArticle

Clinical Outcomes of Immature Teeth Treated with Regenerative Endodontic Procedures—A San Antonio Study

Chrepa, V., Joon, R., Austah, O., Diogenes, A., Hargreaves, K. M., Ezeldeen, M. & Ruparel, N. B., Aug 2020, In : Journal of endodontics. 46, 8, p. 1074-1084 11 p.

Research output: Contribution to journalArticle

Development and characterization of a novel reverse microemulsion analgesic delivery system capable of reducing post-burn mechanical allodynia and thermal hyperalgesia

Jockheck-Clark, A. R., Lemon, D. J., Hargreaves, K. M., McMahon, R. E., Salamone, J. C., Stahl, J. M. & Hwang, Y. Y., Oct 2020, In : Journal of Drug Delivery Science and Technology. 59, 101862.

Research output: Contribution to journalArticle

Endodontic Peri-implant Defects: A New Disease Entity

Daubert, D., Black, R. M., Chrepa, V. & Kotsakis, G. A., Mar 2020, In : Journal of endodontics. 46, 3, p. 444-448 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Human dental stem cells of the apical papilla associated to BDNF-loaded pharmacologically active microcarriers (PAMs) enhance locomotor function after spinal cord injury

Kandalam, S., De Berdt, P., Ucakar, B., Vanvarenberg, K., Bouzin, C., Gratpain, V., Diogenes, A., Montero-Menei, C. N. & des Rieux, A., Sep 25 2020, In : International Journal of Pharmaceutics. 587, 119685.

Research output: Contribution to journalArticle

Implementation of a modified quality assurance protocol for cBct machines within Ut health san antonio school of Dentistry

Moghaddam, A. S., Kats, J. C., Katkar, R., Diogenes, A. R., Yeh, C. K. & Thomas Deahl, S., 2020, In : Dentomaxillofacial Radiology. 49, 2, 20190229.

Research output: Contribution to journalArticle

Neuroendocrine mechanisms governing sex differences in hyperalgesic priming involve prolactin receptor sensory neuron signaling

Paige, C., Barba-Escobedo, P. A., Mecklenburg, J., Patil, M., Goffin, V., Grattan, D. R., Dussor, G., Akopian, A. N. & Price, T. J., Sep 9 2020, In : Journal of Neuroscience. 40, 37, p. 7080-7090 11 p.

Research output: Contribution to journalArticle

Predicting the response of the dental pulp to SARS-CoV2 infection: a transcriptome-wide effect cross-analysis

Galicia, J. C., Guzzi, P. H., Giorgi, F. M. & Khan, A. A., 2020, (Accepted/In press) In : Genes and Immunity.

Research output: Contribution to journalArticle

Open Access

Regenerative Endodontics: A Potential Solution for External Root Resorption (Case Series)

Yoshpe, M., Einy, S., Ruparel, N., Lin, S. & Kaufman, A. Y., Feb 2020, In : Journal of endodontics. 46, 2, p. 192-199 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Sensitization of small-diameter sensory neurons is controlled by TRPV1 and TRPA1 association

Patil, M. J., Salas, M., Bialuhin, S., Boyd, J. T., Jeske, N. A. & Akopian, A. N., Jan 1 2020, In : FASEB Journal. 34, 1, p. 287-302 16 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

The cellular basis of protease-activated receptor 2–evoked mechanical and affective pain

Hassler, S. N., Kume, M., Mwirigi, J. M., Ahmad, A., Shiers, S., Wangzhou, A., Ray, P. R., Belugin, S. N., Naik, D. K., Burton, M. D., Vagner, J., Boitano, S., Akopian, A. N., Dussor, G. & Price, T. J., Jun 4 2020, In : JCI Insight. 5, 11, e137393.

Research output: Contribution to journalArticle

Open Access

The prolactin receptor long isoform regulates nociceptor sensitization and opioid-induced hyperalgesia selectively in females

Chen, Y., Moutal, A., Navratilova, E., Kopruszinski, C., Yue, X., Ikegami, M., Chow, M., Kanazawa, I., Bellampalli, S. S., Xie, J., Patwardhan, A., Rice, K., Fields, H., Akopian, A., Neugebauer, V., Dodick, D., Khanna, R. & Porreca, F., Feb 5 2020, In : Science translational medicine. 12, 529, eaay7550.

Research output: Contribution to journalArticle

2 Scopus citations

To Drill or Not to Drill: Management of Endodontic Emergencies and In-Process Patients during the COVID-19 Pandemic

Patel, B., Eskander, M. A. & Ruparel, N. B., 2020, (Accepted/In press) In : Journal of endodontics.

Research output: Contribution to journalArticle

Open Access

Transcriptomic sex differences in sensory neuronal populations of mice

Mecklenburg, J., Zou, Y., Wangzhou, A., Garcia, D., Lai, Z., Tumanov, A. V., Dussor, G., Price, T. J. & Akopian, A. N., Dec 1 2020, In : Scientific reports. 10, 1, 15278.

Research output: Contribution to journalArticle

Open Access

Trigeminal Sensory Neurons and Pulp Regeneration

Diogenes, A., Sep 2020, In : Journal of endodontics. 46, 9, p. S71-S80

Research output: Contribution to journalArticle

Open Access
2019

3D-Imaging of Whole Neuronal and Vascular Networks of the Human Dental Pulp via CLARITY and Light Sheet Microscopy

França, C. M., Riggers, R., Muschler, J. L., Widbiller, M., Lococo, P. M., Diogenes, A. & Bertassoni, L. E., Dec 1 2019, In : Scientific reports. 9, 1, 10860.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Comparative Biocompatibility and Osteogenic Potential of Two Bioceramic Sealers

Giacomino, C. M., Wealleans, J. A., Kuhn, N. & Diogenes, A., Jan 2019, In : Journal of endodontics. 45, 1, p. 51-56 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Depiction of Oral Tumor-Induced Trigeminal Afferent Responses Using Single-Fiber Electrophysiology

Grayson, M., Furr, A. & Ruparel, S., Dec 1 2019, In : Scientific reports. 9, 1, 4574.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Direct and Indirect Effect of Chlorhexidine on Survival of Stem Cells from the Apical Papilla and Its Neutralization

Widbiller, M., Althumairy, R. I. & Diogenes, A. R., Feb 1 2019, In : Journal of Endodontics. 45, 2, p. 156-160 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Does apical papilla survive and develop in apical periodontitis presence after regenerative endodontic procedures?

Palma, P. J., Martins, J., Diogo, P., Sequeira, D., Ramos, J. C., Diogenes, A. & Santos, J. M., Oct 1 2019, In : Applied Sciences (Switzerland). 9, 19, 3942.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Dural calcitonin gene-related peptide produces female-specific responses in rodent migraine models

Avona, A., Burgos-Ega, C., Burton, M. D., Akopian, A. N., Price, T. J. & Dussor, G., May 29 2019, In : Journal of Neuroscience. 39, 22, p. 4323-4331 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Effect of a Residual Biofilm on Release of Transforming Growth Factor β1 from Dentin

Cameron, R., Claudia, E., Ping, W., Erin, S. & Ruparel, N. B., Jan 1 2019, In : Journal of endodontics.

Research output: Contribution to journalArticle

7 Scopus citations

Endosomal TLR-8 Senses microRNA-1294 Resulting in the Production of NFḱB Dependent Cytokines

Pluta, L., Yousefi, B., Damania, B. & Khan, A. A., Dec 6 2019, In : Frontiers in immunology. 10, 2860.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Expression of Neurotrophic Factors in Human Dentin and Their Regulation of Trigeminal Neurite Outgrowth

Austah, O., Widbiller, M., Tomson, P. L. & Diogenes, A., Apr 2019, In : Journal of endodontics. 45, 4, p. 414-419 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Neurotrophic Proteins in Dentin and Their Effect on Trigeminal Sensory Neurons

Widbiller, M., Austah, O., Lindner, S. R., Sun, J. & Diogenes, A., Jun 2019, In : Journal of endodontics. 45, 6, p. 729-735 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Prolactin receptor expression in mouse dorsal root ganglia neuronal subtypes is sex-dependent

Patil, M., Hovhannisyan, A. H., Wangzhou, A., Mecklenburg, J., Koek, W., Goffin, V., Grattan, D., Boehm, U., Dussor, G., Price, T. J. & Akopian, A. N., 2019, In : Journal of Neuroendocrinology. 31, 8, e12759.

Research output: Contribution to journalArticle

3 Scopus citations

Prolactin Regulates Pain Responses via a Female-Selective Nociceptor-Specific Mechanism

Patil, M., Belugin, S., Mecklenburg, J., Wangzhou, A., Paige, C., Barba-Escobedo, P. A., Boyd, J. T., Goffin, V., Grattan, D., Boehm, U., Dussor, G., Price, T. J. & Akopian, A. N., Oct 25 2019, In : iScience. 20, p. 449-465 17 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Transcriptome analysis of the human tibial nerve identifies sexually dimorphic expression of genes involved in pain, inflammation, and neuro-immunity

Ray, P. R., Khan, J., Wangzhou, A., Tavares-Ferreira, D., Akopian, A. N., Dussor, G. & Price, T. J., Feb 12 2019, In : Frontiers in Molecular Neuroscience. 12, 37.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations
2018

A Comparison of 3 Quantitative Radiographic Measurement Methods for Root Development Measurement in Regenerative Endodontic Procedures

Sutam, N., Jantarat, J., Ongchavalit, L., Sutimuntanakul, S. & Hargreaves, K. M., Nov 1 2018, In : Journal of Endodontics. 44, 11, p. 1665-1670 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Apical Foramen Position in Relation to Proximal Root Surfaces of Human Permanent Teeth Determined by Using a New Cone-beam Computed Tomographic Software

Estrela, C., Couto, G. S., Bueno, M. R., Bueno, K. G., Estrela, L. R. A., Porto, O. C. L. & Diogenes, A., Nov 2018, In : Journal of endodontics. 44, 11, p. 1741-1748 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Characteristics of sensory neuronal groups in CGRP-cre-ER reporter mice: Comparison to Nav1.8-cre, TRPV1-cre and TRPV1-GFP mouse lines

Patil, M. J., Hovhannisyan, A. H. & Akopian, A. N., Jun 2018, In : PloS one. 13, 6, e0198601.

Research output: Contribution to journalArticle

11 Scopus citations

Characterization of sensory neuronal subtypes innervating mouse tongue

Wu, P., Arris, D., Grayson, M., Hung, C. N. & Ruparel, S., Nov 2018, In : PloS one. 13, 11, e0207069.

Research output: Contribution to journalArticle

1 Scopus citations

Comprehensive Characterization of 2 Immature Teeth Treated with Regenerative Endodontic Procedures

Austah, O., Joon, R., Fath, W. M., Chrepa, V., Diogenes, A., Ezeldeen, M., Couve, E. & Ruparel, N. B., Dec 1 2018, In : Journal of Endodontics. 44, 12, p. 1802-1811 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Development of a new cone - Beam computed tomography software for endodontic diagnosis

Bueno, M. R., Estrela, C., Azevedo, B. C. & Diogenes, A. R., Nov 1 2018, In : Brazilian Dental Journal. 29, 6, p. 517-529 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Effect of 3 Bioceramic Materials on Stem Cells of the Apical Papilla Proliferation and Differentiation Using a Dentin Disk Model

Miller, A. A., Takimoto, K., Wealleans, J. & Diogenes, A., Apr 2018, In : Journal of endodontics. 44, 4, p. 599-603 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Effect of Bioceramic Materials on Proliferation and Odontoblast Differentiation of Human Stem Cells from the Apical Papilla

Wongwatanasanti, N., Jantarat, J., Sritanaudomchai, H. & Hargreaves, K. M., Jan 1 2018, (Accepted/In press) In : Journal of Endodontics.

Research output: Contribution to journalArticle

13 Scopus citations

Infection Control in Teeth with Apical Periodontitis Using a Triple Antibiotic Solution or Calcium Hydroxide with Chlorhexidine: A Randomized Clinical Trial

Arruda, M. E. F., Neves, M. A. S., Diogenes, A., Mdala, I., Guilherme, B. P. S., Siqueira, J. F. & Rôças, I. N., Oct 2018, In : Journal of endodontics. 44, 10, p. 1474-1479 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Oral Sciences PhD Program Enrollment, Graduates, and Placement: 1994 to 2016

Herzog, C. R., Berzins, D. W., DenBesten, P., Gregory, R. L., Hargreaves, K. M., Messer, R. L. W., Mina, M., Mooney, M. P., Paine, M. L., Phillips, C., Presland, R. B., Quivey, R. G., Scannapieco, F. A., Sheridan, J. F., Svoboda, K. K. H., Trackman, P. C., Walker, M. P., Walker, S. G., Wang, C. Y. & Hu, J. C. C., May 1 2018, In : Journal of dental research. 97, 5, p. 483-491 9 p.

Research output: Contribution to journalArticle

Pituitary hormones and orofacial pain

Dussor, G., Boyd, J. T. & Akopian, A. N., Oct 2 2018, In : Frontiers in Integrative Neuroscience. 12, 42.

Research output: Contribution to journalArticle

Serum response factor mediates nociceptor inflammatory pain plasticity

Gomez, R., Kohler, D. M., Brackley, A. D., Henry, M. A. & Jeske, N. A., May 1 2018, In : Pain Reports. 3, 3, e658.

Research output: Contribution to journalArticle

1 Scopus citations

Stem cells from human apical papilla decrease neuro-inflammation and stimulate oligodendrocyte progenitor differentiation via activin-A secretion

De Berdt, P., Bottemanne, P., Bianco, J., Alhouayek, M., Diogenes, A., Llyod, A., Gerardo-Nava, J., Brook, G. A., Miron, V., Muccioli, G. G. & Rieux, A. D., Aug 1 2018, In : Cellular and Molecular Life Sciences. 75, 15, p. 2843-2856 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

The burden of disease in Greece, health loss, risk factors, and health financing, 2000–16: an analysis of the Global Burden of Disease Study 2016

Global Burden of Disease 2016 Greece Collaborators, Aug 2018, In : The Lancet Public Health. 3, 8, p. e395-e406

Research output: Contribution to journalArticle

Open Access
25 Scopus citations
2017

A-kinase anchoring protein 79/150 scaffolds transient receptor potential a 1 phosphorylation and sensitization by metabotropic glutamate receptor activation

Brackley, A. D., Gomez, R., Guerrero, K. A., Akopian, A. N., Glucksman, M. J., Du, J., Carlton, S. M. & Jeske, N. A., Dec 1 2017, In : Scientific reports. 7, 1, 1842.

Research output: Contribution to journalArticle

9 Scopus citations

Binary Decision Trees for Preoperative Periapical Cyst Screening Using Cone-beam Computed Tomography

Pitcher, B., Alaqla, A., Noujeim, M. E., Wealleans, J. A., Kotsakis, G. & Chrepa, V., Mar 1 2017, In : Journal of Endodontics. 43, 3, p. 383-388 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Comparative Evaluation of Chemotactic Factor Effect on Migration and Differentiation of Stem Cells of the Apical Papilla

Fayazi, S., Takimoto, K. & Diogenes, A. R., Aug 1 2017, In : Journal of Endodontics. 43, 8, p. 1288-1293 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Cone beam computed tomography image optimization to detect root fractures in endodontically treated teeth: an in vitro (phantom) study

Parrone, M. T., Bechara, B., Deahl Ii, S. T., Ruparel, N. B., Katkar, R. & Noujeim, M. E., May 1 2017, In : Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 123, 5, p. 613-620 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Decellularized Human Dental Pulp as a Scaffold for Regenerative Endodontics

Song, J. S., Takimoto, K., Jeon, M., Vadakekalam, J., Ruparel, N. B. & Diogenes, A. R., Jun 1 2017, In : Journal of Dental Research. 96, 6, p. 640-646 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Effect of Bacterial Biofilm on the Osteogenic Differentiation of Stem Cells of Apical Papilla

Vishwanat, L., Duong, R., Takimoto, K., Phillips, L., Espitia, C. O., Diogenes, A. R., Ruparel, S. B., Kolodrubetz, D. J. & Ruparel, N. B., Jun 1 2017, In : Journal of Endodontics. 43, 6, p. 916-922 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Effects of local and spinal administrations of mu-opioids on postoperative pain in aged vs adult mice

Mecklenburg, J., Patil, M. J., Koek, W. & Akopian, A. N., Jan 1 2017, In : Pain Reports. 2, 1, e584.

Research output: Contribution to journalArticle

1 Scopus citations