Research output per year
Research output per year
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Dive into the research topics where Department of Biochemistry & Structural Biology is active. These topic labels come from the works of this organization's members. Together they form a unique fingerprint.
Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Profiles
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A BCL-xL/BCL-2 PROTAC effectively clears senescent cells in the liver and reduces MASH-driven hepatocellular carcinoma in mice
Yang, Y., Jn-Simon, N., He, Y., Sun, C., Zhang, P., Hu, W., Tian, T., Zeng, H., Basha, S., Huerta, A. S., Sun, L. Z., Yin, X. M., Hromas, R., Zheng, G., Pi, L. & Zhou, D., Mar 2025, In: Nature Aging. 5, 3, p. 386-400 15 p., 15691.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
A novel regimen for pancreatic ductal adenocarcinoma targeting MEK, BCL-xL, and EGFR
Han, S., Tushoski-Alemán, G. W., Zhang, P., Zheng, G., Zhou, D., Huo, Z., Licht, J., George, T. J., Allegra, C., Trevino, J. G. & Hughes, S. J., Jan 2025, In: Neoplasia (United States). 59, 101070.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A Senescent Cluster in Aged Human Hematopoietic Stem Cell Compartment as Target for Senotherapy
Poisa-Beiro, L., Landry, J. J. M., Yan, B., Kardorff, M., Eckstein, V., Villacorta, L., Krammer, P. H., Zaugg, J., Gavin, A. C., Benes, V., Zhou, D., Raffel, S. & Ho, A. D., Jan 2025, In: International journal of molecular sciences. 26, 2, 787.Research output: Contribution to journal › Article › peer-review
Open Access
Datasets
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Structure of rat nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-((5-(6-aminopyridin-2-yl)pentyl)oxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Huang, H. (Contributor), Ji, H. (Contributor), Li, H. (Contributor), Jing, Q. (Contributor), Labby, K. J. (Contributor), Martásek, P. (Contributor), Roman, L. J. (Contributor), Poulos, T. L. (Contributor) & Silverman, R. B. (Contributor), Protein Data Bank (PDB), Jul 11 2012
DOI: 10.2210/pdb3UFW/pdb, https://www.wwpdb.org/pdb?id=pdb_00003ufw
Dataset
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Structure of rat nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(4-(3-chloro-5-fluorophenoxy)butoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Huang, H. (Contributor), Ji, H. (Contributor), Li, H. (Contributor), Jing, Q. (Contributor), Labby, K. J. (Contributor), Martásek, P. (Contributor), Roman, L. J. (Contributor), Poulos, T. L. (Contributor) & Silverman, R. B. (Contributor), Protein Data Bank (PDB), Jul 11 2012
DOI: 10.2210/pdb3UFT/pdb, https://www.wwpdb.org/pdb?id=pdb_00003uft
Dataset
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Structure of rat nitric oxide synthase heme domain in complex with 4-methyl-6-(((3R,4R)-4-((5-(4-methylpyridin-2-yl)pentyl)oxy)pyrrolidin-3-yl)methyl)pyridin-2-amine
Huang, H. (Contributor), Ji, H. (Contributor), Li, H. (Contributor), Jing, Q. (Contributor), Labby, K. J. (Contributor), Martásek, P. (Contributor), Roman, L. J. (Contributor), Poulos, T. L. (Contributor) & Silverman, R. B. (Contributor), Protein Data Bank (PDB), Jul 11 2012
DOI: 10.2210/pdb3UFV/pdb, https://www.wwpdb.org/pdb?id=pdb_00003ufv
Dataset