Additional file 3: of Preclinical rationale for entinostat in embryonal rhabdomyosarcoma

  • Narendra Bharathy (Contributor)
  • Noah Berlow (Creator)
  • Eric Wang (Creator)
  • Jinu Abraham (Contributor)
  • Teagan P. Settelmeyer (Creator)
  • Jody E. Hooper (Creator)
  • Matthew N. Svalina (Creator)
  • Zia Bajwa (Creator)
  • Martin W. Goros (Creator)
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  • Johannes E. Wolff (Creator)
  • Ranadip Pal (Contributor)
  • Angela M. Davies (Creator)
  • Arya Ashok (Contributor)
  • Darnell Bushby (Creator)
  • Maria Mancini (Creator)
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  • Peter Ordentlich (Creator)
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  • Douglas S. Hawkins (Creator)
  • Erin R. Rudzinski (Creator)
  • Atiya Mansoor (Contributor)
  • Theodore J. Perkins (Creator)
  • Christopher R. Vakoc (Creator)
  • Joel E Michalek (Creator)
  • Charles Keller (Creator)
  • Angela M. Davies (Creator)
  • Douglas Hawkins (Creator)

Dataset

Description

Figure S3. CRISPR/Cas9 mediated HDACs inhibition and evaluation of tumor cell growth inhibition in eRMS. (a-e) CRISPR/Cas9 screen for viability of selected HDACs (HDAC1-2 & HDAC10-11) excision by CRISPR in murine eRMS. (f) Q-PCR of murine eRMS U57810 for the expression of myogenic markers of differentiation in vitro. Data normalized to GAPDH expression. Gene expression was quantified using 2â ^dCt method. Myogenin (MYOG), Myoblast determination protein 1 (MyoD) and Myoglobin (Mb). (TIF 2070 kb)
Date made available2019
PublisherFigshare

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