Description
Experimental Technique/Method:X-RAY DIFFRACTION
Resolution:1.28
Classification:TRANSFERASE
Release Date:2015-09-30
Deposition Date:2015-06-10
Revision Date:2015-11-18
Molecular Weight:30810.07
Macromolecule Type:Protein
Residue Count:259
Atom Site Count:2157
DOI:10.2210/pdb5byk/pdb
Abstract:
For over two decades, a racemic mixture of oxamniquine (OXA) was administered to patients infected by Schistosoma mansoni, but whether one or both enantiomers exert antischistosomal activity was unknown. Recently, a ~30 kDa S. mansoni sulfotransferase (SmSULT) was identified as the target of OXA action.
Resolution:1.28
Classification:TRANSFERASE
Release Date:2015-09-30
Deposition Date:2015-06-10
Revision Date:2015-11-18
Molecular Weight:30810.07
Macromolecule Type:Protein
Residue Count:259
Atom Site Count:2157
DOI:10.2210/pdb5byk/pdb
Abstract:
For over two decades, a racemic mixture of oxamniquine (OXA) was administered to patients infected by Schistosoma mansoni, but whether one or both enantiomers exert antischistosomal activity was unknown. Recently, a ~30 kDa S. mansoni sulfotransferase (SmSULT) was identified as the target of OXA action.
| Date made available | 2015 |
|---|---|
| Publisher | RCSB-PDB |